Spontaneous processing of peptides during coagulation of latex from Carica papaya

Plant Science

Volumn 142, Issue 2, 1999, Pages 115-121

  Moutim, V ^a   Silva, L G ^a   Lopes, M T P ^a   Fernandes, G Wilson ^a   Salas, C E ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Carica papaya; Cysteine proteinase; Endopeptidase; Latex coagulation; Papain

Indexed keywords

AMIDASE; CYSTEINE PROTEINASE; LATEX; PAPAIN;

ARTICLE; ENZYME ACTIVITY; NONHUMAN; PLANT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROCESSING;

CARICA PAPAYA;

EID: 0033614254     PISSN: 01689452     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9452(98)00226-X     Document Type: Article

References (31)

1. Farrel B.D., Dussourd D.E., Mitter C. Escalation of plant defense: do latex and resin canals spur plant diversification? Am. Nat. 138:1991;881-900.
2. Joel D.M. Resin ducts in the mango fruit: a defense system. J. Exp. Bot. 31:1980;1707-1718.
3. Dussourd D.E., Eisner T. Vein-cutting behavior: insect counterploy to the latex defense of plants. Science. 237:1987;898-901.
4. Gidrol X., Chrestin H., Tan H.L., Kush A. Hevein; a lectin-like protein from Hevea brasiliensis (rubber-tree) is involved in the coagulation of latex. J. Biol. Chem. 269:1994;9278-9283.
5. Dubois T., Jacquet A., Schnek A.G., Looze Y. The thiol proteinases from the latex of Carica papaya L. Biol. Chem. Hoppe-Seyler. 369:1988;733-740.
6. Mitchel R.E.J., Chaiken I.M., Smith E.L. The complete amino acid sequence of papain. J. Biol. Chem. 245:1970;3485-3492.
7. Watson C., Yaguchi M., Lynn K.R. The aminoacid sequence of chymopapain from Carica papaya. Biochem. J. 266:1990;75-81.
8. Barrett A.J., Buttle D.J. Names and numbers of papaya proteinases. Biochem. J. 228:1985;527.
9. Ritonja A., Buttle D.J., Rawlings N.D., Turk V., Barrett A.J. Papaya proteinase IV aminoacid sequence. FEBS Lett. 258:1989;109-112.
10. Dubois T., Kleinschmidt T., Schnek A.G., Looze Y., Braunitzer G. The thiol proteinases from the latex of Carica papaya L.: the primary structure of proteinase omega. Biol. Chem. Hoppe-Seyler. 369:1988;741-754.
11. Furie B., Furie B.C. The molecular base of blood coagulation. Cell. 53:1988;505-518.
12. Silva L.G., Garcia O., Lopes M.T.P., Salas C.E. Changes in protein profile during coagulation of latex from Carica papaya. Braz. J. Med. Biol. Res. 30:1997;615-619.
13. Bradford M.M. A rapid sensitive method for the quantitation of microgram protein utilizing the principleof protein-dye binding. Anal. Biochem. 72:1976;248-254.
14. Laemmli U.K. Protein electrophoresis in slab gels. Nature. 227:1970;680-683.
15. Reisfeld R.A., Lewis U.J., Williams O.E. Protein electrophoresis separation under acidic conditions. Nature. 195:1962;281-283.
16. Schoenle E.J., Adams L.D., Sammons D.W. Insulin-induced rapid decrease of a major protein in fat cell plasma membranes. J. Biol. Chem. 259:1984;12112-12116.
17. Bravo L.M., Hermosilla L., Salas C.E. A biochemical comparison between latex from C. candamarcensis and C. papaya. Braz. J. Med. Biol. Res. 27:1994;2831-2842.
18. Gravina de Moraes M., Termignoni C., Salas C.E. Biochemical characterization of a new cystein endopeptidase from Carica candamarcensis L. Plant Sci. 102:1994;11-18.
19. Maksymowych R., Ledbetter M.C. Fine structure of epithelial canal cells in petioles of Xanthium pensylvanicum. Am. J. Bot. 74:1987;65-73.
20. Langenheim J.H., Foster C.E., McGinley R.B. Inhibitory effects of different quantitative compositions of Hymenaenaea leaf resins on a generalist herbivore Spodoptera exigua. Biochem. Sys. Ecol. 8:1980;385-396.
21. Shukla O.P., Krishna Murti C.R. The biochemistry of plant latex. J. Sci. Ind. Res.(India). 30:1971;640-662.
22. Camm E.L., Wat C., Towers G.H.N. An assessment of the role of furanocumarins in Heracleum lanatum. Can. J. Bot. 54:1976;2562-2566.
23. Ballansard G., Zamble D., Dumenil G., Cremieux A. Mise en evidence des proprietes antimicrobiennes du latex obtenu par incision du tronc de Alafia multiflora stapf; identification de l'acide vanillique. Plantes Med. Phyto. 14:1980;99-104.
24. McDowell P.G., Lwande W., Deans S.G., Waterman P.G. Volatile resin exudate from stem bark of Commiphora rostrata: potential role in plant defense. Phytochemistry. 27:1988;2519-2521.
25. Polgar L. Problems of classification of papaya latex proteinases. Biochem. J. 221:1984;555-556.
26. Brocklehurst K., Salih E. Fresh non-fruit latex of Carica papaya, contains papain, multiple forms of chymopapain and papaya proteinase Ω Biochem. J. 228:1985;525-527.
27. Brocklehurst K., Kierstan M.P.J. Propapain and its conversion to papain: a new type of zymogen activation mechanism involving intramolecular thiol-disulphide interchange. Nat. New Biol. 242:1973;167-170.
28. Cohen L.W., Fluharty C., Dihel L. The synthesis of papain in Escherichia coli. Gene. 88:1990;263-267.
29. Taylor M.A.J., Baker K.C., Briggs G.S. et al. Recombinants proregions of papain and papaya proteinase IV are selective high affinity inhibitors of the mature papaya enzymes. Prot. Eng. 8:1995;59-62.
30. Hayashi K., Takehisa T., Hamato N., Takano R., Hara S., Miyata T., Kato H. Inhibition of serine proteases of the blood coagulation system by squash family protease inhibitors. J. Biochem. 116:1994;1013-1018.
31. Ryan C.A., An G. Molecular biology of wound-inducible proteinase inhibitors in plants. Plant Cell Environ. 11:1988;345-349.