EVEC, a novel epidermal growth factor-like repeat-containing protein upregulated in embryonic and diseased adult vasculature

Circulation Research

Volumn 84, Issue 10, 1999, Pages 1166-1176

  Kowal, Robert C ^a,b   Richardson, James A ^a   Miano, Joseph M ^c   Olson, Eric N ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Atherosclerosis; EVEC; Restenosis; Vascular smooth muscle cell

Indexed keywords

BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; FETOPROTEIN; FIBRILLIN; FIBULIN; MESSENGER RNA; PROTEIN EVEC; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL INJURY; CONTROLLED STUDY; DISEASE ASSOCIATION; EMBRYO; EMBRYO DEVELOPMENT; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; RAT; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION; VASCULAR SMOOTH MUSCLE;

EID: 0033612354     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.84.10.1166     Document Type: Article

References (48)

1. Schwartz SM, deBlois D, O'Brien ER. The intima: soil for atherosclerosis and restenosis. Circ Res. 1995;77:445-465.
2. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
3. Owens GK. Regulation of differentiation of vascular smooth muscle cells. Physiol Rev. 1995;76:487-517.
4. Katoh Y, Periasamy M. Growth and differentiation of smooth muscle cells during vascular development. Trends Cardiovasc Med. 1996;6: 100-106.
5. Hanahan D. Signaling vascular morphogenesis and maintenance. Nature. 1997;277:48-50.
6. Carmeliet P, Collen D. Genetic analysis of blood vessel formation. Trends Cardiovasc Med. 1997;7:271-280.
7. 1 knock-out mice. Development. 1995;121:1845-1854.
8. Leveen P, Gebre-Medhin S, Swolin B, Larsson E, Betsholtz C. Mice deficient for PDGF B show renal, cardiovascular and hematological abnormalities. Genes Dev. 1994;8:1875-1887.
9. Majesky MW, Lindner V, Twardzik DR, Schwartz SM, Reidy MA. Production of transforming growth factor β1 during repair of arterial injury. J Clin Invest. 1991;88:904-910.
10. Majesky MW, Giachelli CM, Schwartz SM. Rat carotid neointimal smooth muscle cells re-express a developmentally regulated phenotype during repair of arterial injury. Circ Res. 1992;71:759-768.
11. Igura T, Kawata S, Miyagawa J-I, Inui Y, Tamura S, Fukuda K, Isozaki K, Yamamori K, Taniguchi N, Higashiyama S, Matsuzawa Y. Expression of heparin-binding epidermal growth factor-like growth factor in neointimal cells induced by balloon injury in rat carotid arteries. Arterioscler Thromb Vasc Biol. 1996;16:1524-1531.
12. Connolly A, Ishihara H, Kahn ML, Farese RV Jr, Coughlin SR. Role of the thrombin receptor in development and evidence for a second receptor. Nature. 1996;381:516-519.
13. Darrow AL, Fung-Leung WP, Ye RD, Santulli RJ, Cheung WM, Derian CK, Burns CL, Damiano BP, Zhou L, Keenan CM, Peterson PA, Andrade-Gordon P. Biological consequences of thrombin receptor deficiency in mice. Thromb Haemost. 1996;74:1-6.
14. Carmeliet P, Mackman N, Moons L, Luther T, Gressens P, Vlaenderen IV, Demunck H, Kasper M, Breier G, Evrard P, Muller M, Risau W, Edgington T, Collen D. Role of tissue factor in embryonic blood vessel development. Nature. 1996;383:73-75.
15. Takada M, Tanaka H, Yamada T, Ito O, Kogushi M, Yanagimachi M, Kawamura T, Musha T, Yoshida F, Ito M, Kobayashi H, Yoshitake S, and Saito I. Antibody to thrombin receptor inhibits neointimal smooth muscle cell accumulation without causing inhibition of platelet aggregation or altering hemostatic parameters after angioplasty in rat. Circ Res. 1998; 82:980-987.
16. Li DY, Brooke B, Davis EC, Mecham RP, Sorensen LK, Boak BB, Eichwald B, Keating MT. Elastin is an essential determinant of arterial morphogenesis. Nature. 1998;393:276-280.
17. Rothman A, Kulik TJ, Taubman MB, Berk BC, Smith CW, Nadal-Ginard B. Development and characterization of a cloned rat pulmonary arterial smooth muscle cell line that maintains differentiated properties through multiple subcultures. Circulation. 1992;86:1977-1985.
18. Firulli AB, Han D, Kelly-Roloff L, Koteliansky VE, Schwartz SM, Olson EM, Miano JM. A comparative molecular analysis of four rat smooth muscle cell lines. In Vitro Cell Dev Biol. 1998;34:217-226.
19. Lecka-Czernik B, Lumpkin CK, Goldstein S. An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesis. Mol Cell Biol. 1995;15:120-128.
20. Molkentin JD, Lu J-R, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 1998;93:215-228.
21. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Press; 1989;7.37-7.51.
22. Diatcheenko L, Lau YF, Campbell AP, Chenchik A, Moqadam F, Huang B, Lukyanov S, Lukyanov K, Gurskaya N, Sverdlov ED, Siebert PD. Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc Natl Acad Sci U S A. 1996;93:6025-6030.
23. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Press; 1989:1.90-1.104.
24. Sanan DA, Newland DL, Tao R, Marcovina S, Wang J, Mooser V, Hammer RE, Hobbs HH. Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a). Proc Natl Acad Sci U S A. 1998;95:4544-4549.
25. Clowes AW, Reidy MA, Clowes MM. Kinetics of cellular proliferation after arterial injury, I: smooth muscle growth in the absence of endothelium. Lab Invest. 1983;49:327-333.
26. Benjamin I, Shelton J, Garry D, Richardson J. Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development. Dev Dyn. 1997;208:75-84.
27. von Heinje G. How signal sequences maintain cleavage specificity. J Mol Biol. 1984;173:243-251.
28. Nakai K. PSORT: Prediction of protein sorting signals and localization sites in amino acid sequences. Institute for Molecular and Cellular Biology, Osaka University, Japan. Available at: http://psort.nibb.ac.jp/. Accessed April 7, 1999.
29. Handford PA, Mayhew M, Baron M, Winship PR, Campbell ID, Brownlee GG. Key residues involved in calcium-binding motifs in EGF-like domains. Nature. 1991;351:164-167.
30. Hynes R, Bader B. Targeted mutations in integrins and their ligands: their implications for vascular biology. Thromb Haemost. 1997;78:83-87.
31. Ozaki T, Kondo K, Nakamura Y, Ichimiya S, Nakagawara A, Sakiyama S. Interaction of DA41, a DAN-binding protein, with the epidermal growth factor-like protein, S1-5. Biochem Biophys Res Commun. 1997; 237:245-250.
32. Ikegawa S, Toda T, Okui K, Nakamura Y. Structure and chromosomal assignment of the human S1-5 Gene (FBNL) that is highly homologous to fibrillin. Genomics. 1996;35:590-592.
33. Ya J, van den Hoff M, de Boer P, Tesink-Taekema S, Franco D, Moorman A, Lamers W. Normal development of the outflow tract in the rat. Circ Res. 1998;82:464-472.
34. Fang J, Li X, Smiley E, Franke U, Mecham RP, Bonadio J. Mouse latent TGFβ binding protein-2: molecular cloning and developmental expression. Biochem Biophys Acta. 1997;1354:219-230.
35. Belknap J, Grieshaber N, Schwartz P, Orton E, Reidy M, Majack R. Tropoelastin gene expression in individual vascular smooth muscle cells. Circ Res. 1996;78:388-394.
36. Kielty CM, Shuttleworth CA. Fibrillin-containing microfibrils: structure and function in health and disease. Int J Biochem Cell Biol. 1995;27: 747-760.
37. Pan T-C, Sasaki T, Zhang R-Z, Fassler R, Timpl R, Chu M-L. Structure and expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding. J Cell Biol. 1993;123:1269-1277.
38. Argraves W, Dickerson K, Burgess W, Ruoslahti E. Fibulin, a novel protein that interacts with the fibronectin receptor beta subunit cytoplasmic domain. Cell. 1989;58:623-629.
39. Nakajima Y, Miyazono K, Kato M, Takase M, Yamagishi T, Nakamura H. Extracellular fibrillar structure of latent TGFβ binding protein-1: role in TGFβ-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart. J Cell Biol. 1997;136:193-204.
40. Wharton K, Johansen K, Xu T, Artavanis-Tsakonas S. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell. 1985; 43:567-581.
41. Furie B, Furie B. The molecular basis of blood coagulation. Cell. 1988; 53:505-518.
42. Dietz HC, Saraiva J, Pyeritz RE, Cutting GR, Francomano CA. Clustering of fibrillin missense mutation in Marfan syndrome patients at cysteine residues in EGF-like domains. Hum Mutat. 1992;1:366-374.
43. Adam S, Gohring W, Wiedemann H, Chu M-L, Timpl R, Kostka G. Binding of fibulin-1 to nidogen depends on its C-terminal globular domain and a specific array of calcium-binding epidermal growth factor-like modules. J Mol Biol. 1997;272:226-236.
44. Tran H, Mattei M, Godyna S, Argraves W. Human fibulin-1D: molecular cloning, expression and similarity with S1-5 protein, a new member of the fibulin gene family. Matrix Biol. 1997;15:479-493.
45. Enomoto H, Ozaki T, Takahashi E, Nomura N, Tabata S, Takahashi H, Ohnuma N, Tanabe M, Iwai J, Yoshida H, Matunaga T, Sakiyama S. Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus. Oncogene. 1994;9:2785-2791.
46. Dong L-J, Hsieh J-C, Chung A. Two distinct cell attachment sites in entactin are revealed by amino acid substitutions and deletion of the RGD sequence in the cysteine-rich growth factor repeat-2. J Biol Chem. 1995; 270:15838-15843.
47. Couto J, Taylor M, Godwin S, Ceriani R, Peterson J. Cloning and sequence analysis of human breast epithelial antigen BA46 reveals and RGD cell adhesion sequence presented on an epidermal growth factor-like domain. DNA Cell Biol. 1996;15:281-286.
48. Nikkari ST, Jarvelainen HT, Wight TN, Ferguson M, Clowes AW. Smooth muscle cell expression of extracellular matrix genes after arterial injury. Am J Pathol. 1994;144:1348-1356.