Processing of ARIA and release from isolated nerve terminals

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 354, Issue 1381, 1999, Pages 411-416

  Han, Bomie ^a   Fischbach, Gerald D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Depolarization; Neuregulin; Secretion; Synaptosomes

Indexed keywords

ANIMALIA; ARIA;

EID: 0033611670     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.1999.0394     Document Type: Conference Paper

References (39)

1. Altiok, N., Bessereau, J. L. & Changeux, J. P. 1995 ErbB3 and ErbB2/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate. EMBO J. 14, 1258-4266.
2. Burgess, T. L., Ross, S. L., Qian, Y. X., Brankow, D. & Hu, S. 1995 Biosynthetic processing of neu differentiation factor. Glycosylation trafficking, and regulated cleavage from the cell surface. J. Biol. Chem. 270, 19 188-19 196.
3. Busfield, S. J. (and 10 others) 1997 Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus. Mol. Cell Biol. 17, 4007-4014.
4. Carraway III, K., Weber, J., Unger, M., Ledesma, J., Yu, N., Gassmann, M. & Lai, C. 1997 Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature 387, 512-516.
5. Chang, H., Riese II, D., Gilbert, W., Stern, D. & McMahan, U. 1997 Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature 387, 509-512.
6. Chu, G. C., Moscoso, L. M., Sliwkowski, M. X. & Merlie, J. P. 1995 Regulation of the acetylcholine receptor epsilon subunit gene by recombinant ARIA: an in vitro model for transynaptic gene regulation. Neuron 14, 329-339.
7. + channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity. J. Neurosci. 13, 2118-2125.
8. Ericson, J., Thor, S., Edlund, T., Jessell, T. M. & Yamada, T. 1992 Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science 256, 1555-1560.
9. Falls, D. L., Rosen, K. M., Corfas, G., Lane, W. S. & Fischbach, G. D. 1993 ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72, 801-815.
10. Fischbach, G. D. & Rosen, K. M. 1997 ARIA: a neuromuscular junction neuregulin. A. Rev. Neurosci. 20, 429-458.
11. Goodearl, A. D., Yee, A. G., Sandrock, A. W., Jr., Corfas, G. & Fischbach, G. D. 1995 ARIA is concentrated in the synaptic basal lamina of the developing chick neuromuscular junction. J. Cell Biol. 130, 1423-1434.
12. Gray, E. & Whittaker, V. 1962 The isolation of nerve endings from brain: an electron microscopic study of cell fragments derived by homogenization and centrifugation. J. Anat. 96, 79-88.
13. Hall, Z. W. & Sanes, J. R. 1993 Synaptic structure and development: the neuromuscular junction. Cell 72, 99-121.
14. Holmes, W. E. (and 14 others) 1992 Identification of heregulin, a specific activator of p185erbB2. Science 256, 1205-1210.
15. Kramer, R., Bucay, N., Kane, D. J., Martin, L. E., Tarpley, J. E. & Theill, L. E. 1996 Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Proc. Natl Acad. Sci. USA 93, 4833-4838.
16. Loeb, J. A. & Fischbach, G. D. 1995 ARIA can be released from extracellular matrix through cleavage of a heparin-binding domain. J. Cell Biol. 130, 127-135.
17. Loeb, J. A., Susanto, E. T. & Fischbach, G. D. 1998 The neuregulin precursor proARIA is processed to ARIA after expression on the cell surface by a protein kinase C-enhanced mechanism. Mol. Cell. Neurosci. 11, 77-91.
18. Loeb, J. A., Khurana, T. S., Robbins, J., Yee, A. G. & Fischbach, G. D. 1999 Expression patterns of transmembrane and released forms of neureglin during spinal cord and neuromuscular synapse development. Development. (In the press.)
19. Marchionni, M. A. (and 21 others) 1993 Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system. Nature 362, 312-318.
20. Martinou, J. C., Falls, D. E., Fischbach, G. D. & Merlie, J. P. 1991 Acetylcholine receptor-inducing activity stimulates expression of the epsilon-subunit gene of the muscle acetylcholine receptor. Proc. Natl Acad. Sci. USA 88, 7669-7673.
21. Meier, T., Perez, G. M. & Wallace, B. G. 1995 Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation. J. Cell Biol. 131, 441-451.
22. Meyer, D. & Birchmeier, C. 1995 Multiple essential functions of neuregulin in development. Nature 378, 386-390.
23. Miledi, R. & Zelena, J. 1966 Sensitivity to acetylcholine in rat slow muscle. Nature 210, 855-856.
24. Missias, A. C., Chu, G. C., Klocke, B. J., Sanes, J. R. & Merlie, J. P. 1996 Maturation of the acetylcholine receptor in skeletal muscle: regulation of the AChR gamma-to-epsilon switch. Devl Biol. 179, 223-2158.
25. Missias, A. C., Mudd, J., Cunningham, J. M., Steinbach, J. H., Merlie, J. P. & Sanes, J. R. 1997 Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an 'adult' acetylcholine receptor subunit. Development 124, 5075-5086.
26. Moscoso, L. M., Chu, G. C., Gautam, M., Noakes, P. G., Merlie, J. P. & Sanes, J. R. 1995 Synapse-associated expression of an acetylcholine receptor-inducing protein. ARIA/ heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle. Devl Biol. 172, 158-169.
27. Nitkin, R. M., Smith, M. A., Magill, C., Fallon, J. R., Yao, Y. M., Wallace, B. G. & McMahan, U. J. 1987 Identification of agrin, a synaptic organizing protein from Torpedo electric organ. J. Cell Biol. 105, 2471-2478.
28. Ozaki, M., Sasner, M., Yano, R., Lu, H. S. & Buonanno, A. 1997 Neuregulin-beta induces expression of an NMDA-receptor subunit. Nature 390, 691-694.
29. Peles, E., Bacus, S. S., Koski, R. A., Lu, H. S., Wen, D., Ogden, S. G., Levy, R. B. & Yarden, Y. 1992 Isolation of the neu/ HER-2 stimulatory ligand: a 14 kd glycoprotein that induces differentiation of mammary tumor cells. Cell 69, 205-216.
30. Rio, C., Rieff, H. I., Qi, P. & Corfas, G. 1997 Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron 19, 39-50.
31. Role, L. W., Matossian, V. R., O'Brien, R. J. & Fischbach, G. D. 1985 On the mechanism of acetylcholine receptor accumulation at newly formed synapses on chick myotubes. J. Neurosci. 5, 2197-2204.
32. Sandrock, A. W. Jr, Goodearl, A. D., Yin, Q. W., Chang, D. & Fischbach, G. D. 1995 ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses. J. Neurosci. 15, 6124-6136.
33. Sandrock, A. W. Jr, Dryer, S. E., Rosen, K. M., Gozani, S. N., Kramer, R., Theill, L. E. & Fischbach, G. D. 1997 Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo. Science 276, 599-603.
34. Tandon, A., Bannykh, S., Kowalchyk, J. A., Banerjee, A., Martin, T. F. & Balch, W. E. 1998 Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes. Neuron 21, 147-154.
35. Tsuchida, T., Ensini, M., Morton, S. B., Baldassare, M., Edlund, T., Jessell, T. M. & Pfaff, S. E. 1991 Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 79, 957-970.
36. Usdin, T. B. & Fischbach, G. D. 1986 Purification and characterization of a polypeptide from chick brain that promotes the accumulation of acetylcholine receptors in chick myotubes. J. Cell Biol. 103, 493-507.
37. Wen, D. (and 12 others) 1992 Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell 69, 559-572.
38. Zhang, D., Sliwkowski, M. X., Mark, M., Frantz, G., Akita, R., Sun, Y., Hillan, K., Crowley, C., Brash, J. & Godowski, P. J. 1997 Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4. Proc. Natl Acad. Sci. USA 94, 9562-9567.
39. Zhu, X., Lai, C., Thomas, S. & Burden, S. J. 1995 Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses. EMBO J. 14, 5842-5848.