Reactive Cysteine Residue of Bovine Brain Glutamate Dehydrogenase Isoproteins

Molecules and Cells

Volumn 9, Issue 1, 1999, Pages 91-98

  Cho, Sung Woo ^a   Cho, Eun Hee ^b   Hwang, Sang Hyun ^a   Choi, Soo Young ^c  

^a University of Ulsan College of Medicine   (South Korea)

^b Chosun University   (South Korea)

^c Hallym University   (South Korea)

Author keywords

Chemical Modification; Glutamate Dehydrogenase Isoproteins; Peptide Mapping; Reactive Cysteine

Indexed keywords

4 CHLOROMERCURIBENZOIC ACID; CARBON; CYSTEINE; GLUTAMATE DEHYDROGENASE; ISOENZYME;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BRAIN; CATTLE; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOUSE; PEPTIDE MAPPING; PHYSIOLOGY; RAT; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CARBON RADIOISOTOPES; CATTLE; CYSTEINE; GLUTAMATE DEHYDROGENASE; HUMANS; ISOENZYMES; MICE; MOLECULAR SEQUENCE DATA; P-CHLOROMERCURIBENZOIC ACID; PEPTIDE MAPPING; RATS; SEQUENCE ALIGNMENT;

EID: 0033611597     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Abe, T., Ishiguro, S. I., Saito, H., Kiyosawa, M., and Tamai, M. (1992) Partially deficient glutamate dehydrogenase activity and attenuated oscillatory potentials in patient with spinocerebellar degeneration. Invest. Ophthalmol. Vis. Sci. 33, 447-452.
2. Amuro, N., Yamaura, M., Goto, Y., and Okazaki, T. (1988) Molecular cloning and nucleotide sequence of the cDNA for human liver glutamate dehydrogenase precursor. Biochem. Biophys. Res. Commun. 152, 1395-1400.
3. Aubby, D., Saggu, H. K., Jenner, P., Quinn, N. P., Harding, A. E., and Marsden, C. D. (1988) Leukocyte glutamate dehydrogenase activity in patients with degenerative neurological disorders. J. Neurol. Neurosurg. Psychiatry 51, 893-902.
4. Bailey, J., Bell, E. T., and Bell, J. E. (1982) Regulation of bovine glutamate dehydrogenase. J. Biol. Chem. 257, 5579-5583.
5. Baker, P. J., Britton, K. L., Rice, D. W., Rob, A., and Stillman T. J. (1992) Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold implications for nucleotide specificity. J. Mol. Biol. 228, 662-671.
6. Bringaud, F., Stripecke, R., French, G. C., Freedland, S., Turck, C., Byrne, E. M., and Simpson, L. (1997) Mitochondrial glutamate dehydrogenase from Leishmania tarentolae is a guide RNA-binding protein. Mol. Cell. Biol. 17, 3915-3923.
7. Bryla, J., Michalik, M., Nelson, J., and Erecinska, M. (1994) Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release. Metabolism 43, 1187-1195.
8. Cavallaro, S., Meiri, N., Yi, C. L., Musco, S., Ma, W., Goldberg, J., and Alkon, D. L. (1997) Late memory-related genes in the hippocampus revealed by RNA fingerprinting. Proc. Natl. Acad. Sci. USA 94, 9669-9673.
9. Cho, S.-W., Ahn, J.-Y., Lee, J., and Choi, S. Y. (1996) Identification of a peptide of the guanosine triphosphate binding site within brain glutamate dehydrogenase isoproteins using 8-azidoguanosine triphosphate. Biochemistry 35, 13907-13913.
10. Cho, S.-W., Cho, E. H., and Choi, S. Y. (1998a) Activation of two types of brain glutamate dehydrogenase isoproteins by gabapentin. FEBS Lett. 426, 196-200.
11. Cho, S.-W., Lee, J., and Choi, S. Y. (1995) Two soluble forms of glutamate dehydrogenase isoproteins from bovine brain. Eur. J. Biochem. 233, 340-346.
12. Cho, S.-W. and Lee, J. E. (1996) Modification of brain glutamate dehydrogenase isoproteins with pyridoxal 5′-phosphate. Biochimie 78, 817-821.
13. Colon, A., Plaitakis, A., Perakis, A., Berl, S., and Clarke, D. D. (1986) Purification and characterization of a soluble and a particulate glutamate dehydrogenase from a rat brain. J. Neurochem. 46, 1811-1819.
14. Cosson M. P., Gros C., and Talbot J. C. (1976) Identification of a cysteine residue of glutamate dehydrogenase. Biochem. Biophys. Res. Commun. 72, 1304-1310.
15. Duvoisin, R. C., Nicklas, W. J, Ritchie, V., Sage, J., and Chokroverty, S. (1988) Low leukocyte glutamate dehydrogenase activity does not correlate with a particular type of multiple system atrophy. J. Neurol. Neurosurg. Psychiatry 51, 1508-1511.
16. Fahien, L. A., MacDonald M. J., Kmiotek, E. H., Mertz, R. J., and Fahien, C. M. (1988) Glutamate dehydrogenase, IV. Studies on enzyme inactivation and coenzyme binding. J. Biol. Chem. 263, 13610-13614.
17. Fisher, H. F. (1985) L-Glutamate dehydrogenase from bovine liver. Methods Enzymol. 113, 16-27.
18. Hussain, M. H., Zannis, V. I., and Plaitakis, A. (1989) Characterization of glutamate dehydrogenase isoproteins purified from the cerebellum of normal subjects and patients with degenerative neurological disorders and from human neoplastic cell lines. J. Biol. Chem. 264, 20730-20735.
19. Julliard, J. and Smith, E. L. (1979) Partial amino acid sequence of the glutamate dehydrogenase of human liver and a revision of the sequence of the bovine enzyme. J. Biol. Chem. 254, 3427-3438.
20. Kim, S. W., Lee, J., Song, M. S., Choi, S. Y., and Cho, S.-W. (1997) Essential active-site lysine of brain glutamate dehydrogenase isoproteins. J. Neurochem. 69, 418-422.
21. Konagaya, Y., Konagaya, M., and Takayanagi, T. (1986) Glutamate dehydrogenase and its isoenzyme activity in olivopontocerebellar atrophy. J. Neurol. Sci. 74, 231-236.
22. Lilley, K. S. and Engel, P. C. (1992) The essential active-site lysines of clostridal glutamate dehydrogenase: A study with pyridoxal-5′-phosphate. Eur. J. Biochem. 207, 533-540.
23. Mak, A. S. and Jones, B. L. (1978) Application of S-pyridylethylation of cysteine to the sequence analysis of proteins. Anal. Biochem. 84, 432-440.
24. Mavrothalassitis, G., Tzimagiorgis, G., Mitsialis, A., Zannis, V. I., Plaitakis, A., Papamatheakis, J., and Moschonas, N. K. (1988) Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family. Proc. Natl. Acad. Sci. USA 85, 3494-3498.
25. McDaniel, H. G. (1995) Comparison of the primary structure of nuclear and mitochondrial glutamate dehydrogenase from bovine liver. Arch. Biochem. Biophys. 319, 316-321.
26. McGeer, E. G. and McGeer, P. L. (1976) Duplication of biochemical changes of Huntington's chorea by intratriatal injection of glutamic and kainic acid. Nature 263, 517-519.
27. Michaelidis, T. M., Tzimagiorgis, G., Moschonas, N. K., and Papamatheakis, J. (1993) The human glutamate dehydrogenase gene family: gene organization and structural characterization. Genomics 16, 150-160.
28. Nakatani, Y., Banner, C., Herrath, M., Schneider, M. E., Smith, H. H., and Freese, E. (1987) Comparison of human and liver glutamate dehydrogenase cDNAs. Biochem. Biophys. Res. Commun. 149, 405-410.
29. Pandey, A., Sheikh, S., and Katiyar, S. S. (1996) Identification of cystein and lysine residues present at the active site of beef liver glutamate dehydrogenase by o-phthalaldehyde. Biochim. Biophys. Acta 1293, 122-128.
30. Peterson, P. E., Pierce, J., and Smith, T. J. (1997) Crystallization and characterization of bovine liver glutamate dehydrogenase. J. Struct. Biol. 120, 73-77.
31. Plaitakis, A., Berl, S., and Yahr, M. D. (1982) Abnormal glutamate dehydrogenase deficiency in three patients with spinocerebellar syndrome. Science 216, 193-196.
32. Plaitakis, A., Berl, S., and Yahr, M. D. (1984) Neurological disorders associated with deficiency of glutamate dehydrogenase. Ann. Neurol. 15, 144-153.
33. Plaitakis, A., Flessas, P., Natsiou, A. B., and Shashidharan, P. (1993) Glutamate dehydrogenase deficiency in cerebellar degenerations: clinical, biochemical and molecular genetic aspects. Can. J. Neurol. Sci. Suppl. 3, S109-S116.
34. Preiss, T., Hall, A. G., and Lightowlers, R. N. (1993) Identification of bovine glutamate dehydrogenase as an RNA-binding protein. J. Biol. Chem. 268, 24523-24526.
35. Rajas, F., Gire, V., and Rouset, B. (1996) Involvement of a membrane-bound form of glutamate dehydrogenase in the association of lysosomes to microtubles. J. Biol. Chem. 271, 29882-29890.
36. Shashidharan, P., Clarke, D. D., Ahmed, N., Moschonas, N., and Plaitakis, A. (1997) Nerve tissue-specific human glutamate dehydrogenase that is thermolabile and highly regulated by ADP. J. Neurochem. 68, 1804-1811.
37. Shashidharan, P., Michaelidis, T. M., Robakis, N. K., Kresovali, A., Papamatheakis, J., and Plaitakis, A. (1994) Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. J. Biol. Chem. 269, 16971-16976.
38. Shemisa, O. A. and Fahien, L. A. (1971) Modification of glutamate dehydrogenase by various drugs which affect behavior. Mol. Pharmacol. 7, 8-25.
39. Stanley, C. A., Lieu, Y. K., Hsu, B. Y. L., Burlina, A. B., Greenberg, C. R., Hopwood, N. J., Perlman, K., Rich, B. H., Zammarchi, E., and Poncz, M. (1998) Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene. New. Engl. J. Med. 338, 1353-1357.
40. Syed, S. E.-H., Hornby, D. P., Brown, P. E., Fitton, J. E., and Engel, P. C. (1994) Site and significance of chemically modifiable cysteine residues in glutamate dehydrogenase of Clostridium symbiosum and the use of protection studies to measure coenzyme binding. Biochem. J. 298, 107-113.
41. Tzimagiorgis, G. and Moschonas, N. K. (1991) Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA. Biochim. Biophys. Acta 1089, 250-253.
42. Valinger, Z., Engel, P. C., and Metzler, D. E. (1993) Is pyridoxal 5′-phosphate an affinity label for phosphate-binding sites in proteins?; The case of bovine glutamate dehydrogenase. Biochem. J. 294, 835-839.
43. Weinzimer, S. A., Stanley, C. A., Berry, G. T., Yudkoff, M., Tuchman, M., and Thornton, P. S. (1997) A syndrome of congenital hyperinsulinism and hyperammonemia. J. Pediatr. 130, 661-664.
44. Yip, K. S. P., Stillman, T. J., Britton, K. L., Artymiuk, P. J., Baker, P. J., Sedelnikova, S. E., Engel, P. C., Pasquo, A., Chiaraluce, R., Consalvi, V., Scandurra, R., and Rice, D. W. (1995) The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures. Structure 3, 1147-1158.
45. Zammarchi, E., Filippi, L., Novembre, E., and Donati, M. A. (1996) Biochemical evaluation of a patient with a familial form of leucine-sensitive hypoglycemia and concomitant hyperammonemia. Metabolism 45, 957-960.