Amyloid β but not bradykinin induces phosphatidylcholine hydrolysis in immortalized rat brain endothelial cells

Neuroscience Letters

Volumn 271, Issue 3, 1999, Pages 155-158

  Haynes, Laurence W ^a   Schmitz, Sabine ^a,b   Clegg, J Christopher S ^b   Fooks, Anthony R ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Amyloid ; Bradykinin; Endothelial cells; Free radicals; Phosphatidylcholine

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; AMYLOID BETA PROTEIN; BRADYKININ; CHOLINE; FREE RADICAL; PHOSPHATIDYLCHOLINE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; GREEN FLUORESCENT PROTEIN; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN L; PHOTOPROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; INFLAMMATION; NONHUMAN; PEROXIDATION; PRIORITY JOURNAL; RADIOASSAY; RAT; ANIMAL; CELL COMMUNICATION; CELL LINE; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; GENE EXPRESSION; GENETICS; HUMAN; METHODOLOGY; MYELIN SHEATH; NERVE CELL; PHYSIOLOGY; PROMOTER REGION; REPORTER GENE; SCHWANN CELL;

ANIMALS; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL LINE, TRANSFORMED; GENE EXPRESSION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; INDICATORS AND REAGENTS; LUMINESCENT PROTEINS; MYELIN SHEATH; NEUROFILAMENT PROTEINS; NEURONS; PROMOTER REGIONS (GENETICS); RATS; SCHWANN CELLS;

EID: 0033609681     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00510-8     Document Type: Article

References (12)

1. Beaudet L., Charron G., Houle D., Tretjakoff I., Peterson A., Julien J.P. Intragenic regulatory elements contribute to transcriptional control of the neurofilament light gene. Gene. 116:1992;205-214.
2. Charron G., Guy L.G., Bazinet M., Julien J.P. Multiple neuron-specific enhancers in the gene encoding for the neurofilament light chain. J. Biol. Chem. 270:1995;30604-30610.
3. Eccleston P.A., Mirsky R., Jessen K.R. Spontaneous immortalization of Schwann cells in culture: short-term cultured Schwann cells secrete growth inhibitory activity. Development. 112:1991;33-42.
4. Fabrizi C., Kelly B.M., Gillespie C.S., Schlaepfer W.W., Scherer S.S., Brophy P.J. Transient expression of the neurofilament proteins NF-L and NF-M by Schwann cells is regulated by axonal contact. J. Neurosci. Res. 50:1997;291-299.
5. Rushton, J.A., Schmitz, S., Gunn-Moore, F., Sherman, D., Pappas, C.A., Ritchie, J.M. and Haynes, L.W., Growth-arrest and spontaneous differentiation are initiated through an autocrine loop in clonally-derived Schwann cells by α1-procollagen I C-propeptide. J. Neurochem., (1999) in press.
6. Jauberteau M.O., Jacque C., Preud Homme J.L., Vallat J.M., Baumann N. Human Schwann cells in culture: characterization and reactivity with human anti-sulfated glucuronyl glycolipid monoclonal lgM antibodies. Neurosci. Lett. 139:1992;161-164.
7. Jessen K.R., Mirsky R. Embryonic Schwann cell development: the biology of Schwann cell precursors and early Schwann cells. J. Anat. 191:1997;501-505.
8. -) depends on growth-inhibition. J. cell. Biol. 112:1991;457-467.
9. Nakahira K., Kazyhiro I., Wada K., Tamura T., Furuichi T., Mikoshiba K. Structure of the 68-kDa neurofilament gene and regulation of its expression. J. Biol. Chem. 265:1990;6-19791.
10. Reeben M., Neuman T., Palgi J., Plam K., Paalme V., Saarma M. Characterization of the rat light neurofilament (NF-L) gene promoter and identification of NGF and cAMP-responsive regions. J. Neurosci. Res. 40:1995;177-188.
11. Roberson M.D., Toews A.D., Goodrum J.F., Morell P. Neurofilament and tubulin mRNA expression in Schwann cells. J. Neurosci. Res. 33:1992;156-162.
12. Yamawaki M., Vasquez A., Younes A.B., Yoshino H., Kanda T., Ariga T., Baumann N., Yu R.K. Sensitization of Lewis rats with sulfoglucuronosyl paragloboside: electrophysiological and immunological studies of an animal model of peripheral neuropathy. J. Neurosci. Res. 44:1996;58-65.