A potent oligosaccharyl transferase inhibitor that crosses the intracellular endoplasmic reticulum membrane

Biochemistry

Volumn 38, Issue 17, 1999, Pages 5430-5437

  Eason, Paula Denney ^a   Imperiali, Barbara ^a  

^a California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; OLIGOSACCHARIDE; TRANSFERASE;

ANTIGEN PRESENTATION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; GLYCOSYLATION; MEMBRANE BINDING; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; PROTEIN TRANSPORT;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE PERMEABILITY; DIFFUSION; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; FEMALE; FUNGAL PROTEINS; GLYCOSYLATION; HEXOSYLTRANSFERASES; INTRACELLULAR MEMBRANES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY; TRANSFERASES;

EID: 0033609127     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982740e     Document Type: Article

References (28)

1. Kaplan, H. A., Welply, J. K., and Lennarz, W. J. (1987) Biochim. Biophys. Acta 906, 161-173.
2. Marshall, R. D. (1972) Annu. Rev. Biochem. 41, 673-702.
3. Keller, R. K., Boon, D. Y., and Crum, F. C. (1979) Biochemistry 18, 3946-3952.
4. Duksin, D., and Mahoney, W. C. (1982) J. Biol. Chem. 257, 3105-3109.
5. Tamura, G. (1982) Tunicamycin, Japan Scientific Society Press, Tokyo.
6. Hendrickson, T. L., Spencer, J. R., Kato, M., and Imperiali, B. (1996) J. Am. Chem. Soc. 118, 7636-7637.
7. Imperiali, B., and O'Connor, S. E. (1998) Pure Appl. Chem. 70 (1), 33-40.
8. Kellenberger, C., Hendrickson, T. L., and Imperiali, B. (1997) Biochemistry 36, 12554-12559.
9. Delli Bovi, P., Curatola, A. M., Kern, F. G., Greco, A., Ittmann, M., and Basilico, C. (1987) Cell 50, 729-737.
10. Rojas, M., Donahue, J. P., Tan, Z., and Lin, Y.-Z. (1998) Nat. Biotechnol. 16, 370-375.
11. Lin, Y.-Z., Yao, S., and Hawiger, J. (1996) J. Biol. Chem. 271, 5305-5308.
12. Du, C., Yao, S., Rojas, M., and Lin, Y.-Z. (1998) J. Pept. Res. 51, 235-243.
13. Heemels, M.-T., and Ploegh, H. (1995) Annu. Rev. Biochem. 64, 463-491.
14. Heemels, M.-T., Schumacher, T. N. M., Wonigeit, K., and Ploegh, H. L. (1993) Science 262, 2059-2063.
15. Momburg, F., Roelse, J., Hammerling, G. J., and Neffjes, J. J. (1994) J. Exp. Med. 179, 1613-1623.
16. Neefjes, J., Gottfried, E., Roelse, J., Gromme, M., Obst, R., Hammerling, G., and Momburg, F. (1995) Eur. J. Immunol. 25, 1133-1136.
17. Atherton, E., and Sheppard, R. C. (1989) Solid phase peptide synthesis, Oxford University Press, New York.
18. Virgilio, A. A., and Ellman, J. A. (1994) J. Am. Chem. Soc. 116, 11580-11581.
19. Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., and Gray, T. (1995) Protein Sci. 4, 2411-2423.
20. Hunter, W. M., and Greenwood, F. C. (1962) Nature 194, 495-496.
21. Pathak, R., Hendrickson, T. L., and Imperiali, B. (1995) Biochemistry 34, 4179-4185.
22. Shepherd, J. C., Schumacher, T. N. M., Ashton-Richardt, P. G., Imaeda, S., Ploegh, H. L., Janeway, C. A., Jr., and Tonewaga, S. (1993) Cell 74, 577-584.
23. Walter, P., and Blobel, G. (1983) Methods Enzymol. 96, 84-93.
24. Schumacher, T. N. M., Kantesaria, D. V., Heemels, M-T., Ashton-Rickardt, P. G., Shepherd, J. C., Fruh, K., Yang, Y., Peterson, P. A., Tonegawa, S., and Ploegh, H. L. (1994) J. Exp. Med. 179, 533-540.
25. Rathod, P. K., Tashjian, A. H., Jr., and Abeles, R. H. (1986) J. Biol. Chem. 261, 6461-6469.
26. Imperiali, B., Shannon, K. L., Unno, M., and Rickert, K. W. (1992) J. Am. Chem. Soc. 114, 7944-7945.
27. Segel, I. H. (1975) Enzyme Kinetics, Wiley, New York.
28. Gavel, Y., and von Heijne, G. (1990) Protein Eng. 3 (5), 433-442.