Triethylborane-induced solid-phase radical cyclization of oxime ethers

Tetrahedron Letters

Volumn 40, Issue 48, 1999, Pages 8387-8390

  Miyabe, Hideto ^a   Tanaka, Hirotaka ^a   Naito, Takeaki ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Oximes; Radical reactions; Solid phase synthesis

Indexed keywords

BORANE DERIVATIVE; ETHER DERIVATIVE; OXIME; POLYMER; PYRROLIDINE DERIVATIVE; RADICAL;

ARTICLE; CHEMICAL BOND; CYCLIZATION; SYNTHESIS;

EID: 0033607738     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01788-8     Document Type: Article

References (24)

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13. Oxime ethers are well known to be excellent radical acceptors. See: (a) Miyabe, H.; Torieda, M.; Inoue, K.; Tajiri, K.; Kiguchi, T.; Naito, T. J. Org. Chem. 1998, 63, 4397.
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15. Wang resin purchased from Novabiochem was used in this study.
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21. 3SnH would not be excluded.
22. The reaction conditions have not been optimized. All reactions were run on scale 200-250 mg beads in commercially available solvents and with reagents without requiring any special precautions.
23. 13C NMR, and HRMS.
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