Incorporation and characterization of abasic and phenyl residues in peptide nucleic acids

Tetrahedron Letters

Volumn 40, Issue 48, 1999, Pages 8333-8336

  Challa, Hemavathi ^a   Woski, Stephen A ^a  

^a UNIVERSITY OF ALABAMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; GLYCINE DERIVATIVE; PEPTIDE NUCLEIC ACID; PHENYLACETIC ACID;

ARTICLE; DRUG SYNTHESIS;

EID: 0033607577     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01781-5     Document Type: Article

References (17)

1. Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Science 1991, 254, 1497-1500.
2. Egholm, M.; Buchardt, O.; Christensen, L.; Behrens, C; Freier, S. M.; Driver, D. A.; Berg, R. H.; Kim, S. K.; Norden, B.; Nielsen, P. E. Nature 1993, 365, 566-568.
3. For some recent reviews, see: (a) Hyrup, B.; Nielsen, P. E. Bioorg. Med. Chem. 1996, 4, 5-23;
4. (b) Dueholm, K. L.; Nielsen, P. E. New. J. Chem. 1997, 21, 19-31;
5. (c) Nielsen, P. E.; Haaima, G. Chem. Soc. Rev. 1997, 73-78.
6. Hamilton, S. E.; Simmons, C. G.; Kathiriya, I. S.; Corey, D. R. Chem. Biol. 1999, 6, 343-351.
7. Leijon, M.; Graeslund, A.; Nielsen, P. E.; Buchardt, O.; Norden, B.; Kristensen, S. M.; Eriksson, M. Biochemistry 1994, 33, 9820-9825.
8. Brown, L. C.; Thomson, S. A.; Veal, J. M.; Davis, D. G. Science 1994, 265, 777-780.
9. Rasmussen, H.; Kastrup, J. S.; Nielsen, J. N.; Nielsen, J. M.; Nielsen, P. E. Nat. Struct. Biol. 1997, 4, 98-101.
10. Challa, H.; Woski, S. A. Tetrahedron Lett. 1999, 40, 419-422.
11. Challa, H.; Styers, M. L.; Woski, S. A. Org. Lett. 1999, in press.
12. Armitage, B.; Koch, T.; Frydenlund, H.; Orum, H.; Schuster, G. B. Nucleic Acids Res. 1998, 26, 715-720.
13. Millican, T. A.; Mock, G. A.; Chauncey, M. A.; Patel, T. P.; Eaton, M. A. W.; Gunning, J.; Cutbush, S. D.; Neidle, S.; Mann, J. Nucleic Acids Res. 1984, 12, 7435-7453.
14. Thomson, S. A.; Josey, J. A.; Cadilla, R.; Gaul, M. D.; Hassman, C. F.; Luzzio, M. J.; Pipe, A. J.; Reed, K. L.; Ricca, D. J.; Wiethe, R. W.; Noble, S. A. Tetrahedron 1995, 51, 6179-6194.
15. PNA Chemistry for the Expedite™ Nucleic Acid Synthesis System. PerSeptive Biosystems, Inc.: Framingham, Massachusetts, 1998.
16. Bergstrom, D. E.; Zhang, P.; Johnson, W. T. Nucleic Acids Res. 1997, 25, 1935-1942.
17. Gralla, J.; Crothers, D. M. J. Mol. Biol. 1973, 78, 301-319.