Toxicity evaluation of petroleum blending streams: Reproductive and developmental effects of light catalytic cracked naphtha distillate in rats

Journal of Toxicology and Environmental Health - Part A

Volumn 58, Issue 6, 1999, Pages 365-382

  Schreiner, Ceinwen A ^a   Bui, Q ^a   Breglia, R ^a   Burnett, D ^a   Koschier, F ^a   Podhasky, P ^a   Lapadula, E ^a   White, R ^a   Schroeder, R E ^b  

^a Petrol Product Stewardship Council   (United States)

^b Huntingdon Life Sciences New Jersey   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCARBON; NAPHTHALENE DERIVATIVE; PETROLEUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONGENITAL DISORDER; CONTROLLED STUDY; FACIAL BONE; FEMALE; FERTILITY; FETUS DEVELOPMENT; GENITAL SYSTEM; KIDNEY MASS; LITTER SIZE; LIVER WEIGHT; MALE; MATING; NEPHROTOXICITY; NEWBORN; NIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCTION; SEXUAL BEHAVIOR; SPLEEN WEIGHT; VAPOR; WEIGHT GAIN;

ALKANES; ANIMALS; BODY WEIGHT; CATALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO IMPLANTATION; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FERTILITY; LITTER SIZE; MALE; ORGAN SIZE; PETROLEUM; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; THRESHOLD LIMIT VALUES;

EID: 0033607459     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/009841099157214     Document Type: Article

References (23)

1. American Petroleum Institute. 1982a. Light Catalytic Cracked Naphtha (API #81-03): Acute Oral Toxicity in Sprague Dawley Rats, Acute Dermal Toxicity in New Zealand White (NZW) Rabbits, Primary Eye Irritation in NZW Rabbits, Primary Skin Irritation in NZW Rabbits. Report 3031988. Washington, DC: API.
2. American Petroleum Institute. 1982b. Acute Inhalation Toxicity of API #81-03 in Sprague Dawley Rats. Report 30-31 902. Washington, DC: API.
3. American Petroleum Institute. 1984a. Dermal Sensitization (Buehler Assay) in Guinea Pigs of API #81-03. Report 31-31412. Washington, DC: API.
4. American Petroleum Institute. 1984b. Acute Inhalation Toxicity of API #81-04 in Sprague Dawley Rats. Report 31-30680. Washington, DC: API.
5. American Petroleum Institute. 1985a. Petroleum Process Stream Terms Included in the Chemical Substances I nventory Under Toxic Substances Control Act (TSCA), p. 7. Washington, DC: API.
6. American Petroleum Institute. 1985b. Light Catalytic Cracked Naphtha (API #81-04): Acute Oral Toxicity in Sprague Dawley Rats, Acute Dermal Toxicity in New Zealand White (NZW) rabbits, Primary Eye Irritation in NZW Rabbits, Primary Skin Irritation in NZW Rabbits. Report 3231708. Washington, DC: API.
7. American Petroleum Institute. 1985c. Dermal Sensitization (Buehler Assay) in Guinea Pigs of API #81-04. Report 33-30495. Washington, DC: API.
8. American Petroleum Institute. 1985d. Mutagenicity of API #81-03 in the Mouse Lymphoma (TK+/-) Cell Culture Assay and In Vivo Bone Marrow Cytogenicity Assay in Sprague Dawley Rats of API #81-03 Administered by Inhalation. Report 32-31300. Washington, DC: API.
9. American Petroleum Institute. 1985e. In Vivo Bone Marrow Cytogenicity Assay in Sprague Dawley Rats of API #81-04 Administered by a Single Intraperitoneal Injection. Report 32-322288. Washington, DC: API.
10. American Petroleum Institute. 1986a. Mutagenicity of API #81-04 in the Mouse Lymphoma (TK+/-) Cell Culture Assay. Report 32-31710. Washington, DC: API.
11. American Petroleum Institute. 1986b. Twenty-Eight Day Dermal Subchronic Toxicity Study of Light Catalytic Cracked Naphtha (API #81-04) in NZW Rabbits. Report 33-30747. Washington, DC: API.
12. American Petroleum Institute. 1987. Thirteen Week Subchronic Inhalation Toxicity Study of Light Catalytic Cracked Naphtha (API #81-03) in Sprague Dawley Rats. Report 34-33173. Washington, DC: API.
13. American Petroleum Institute. 1989. Two Year Chronic Dermal Carcinogenicity Study of Light Catalytic Cracked Naphtha (API #81-03). Report 36-31364. Washington, DC: API.
14. Bui, Q., Breglia, R., Burnett, D., Koschier, F., Lapadula, E., Podhasky, P., Schreiner, C., White, R., Hoffman, G., and Schroeder, R. Nov. 1997. Reproductive and developmental toxicity evaluation of light catalytic reformed naphtha in rats. American College of Toxicology Annual Meeting, Washington, DC.
15. Bui, Q. Q., Burnett, D. M., Breglia, R. J., Koschier, F. J., Lapadula, E. S., Podhasky, P. I., Schreiner, C. A., White, R. D., Dalbey, W. E., and Feuston, M. H. 1998. Toxicity evaluation of petroleum blending streams: Reproductive and developmental effects of a distillate from light alkylate naphtha. J. Toxicol. Environ. Health 53:121-133.
16. CONCAWE. 1999. Two Generation Reproduction Study of Gasoline Vapors in Rats With Vapor Recovery Unit Condensate. Brussels, Belgium: Unpublished.
17. Dalbey, W. E., Feuston, M. H., Yang, J. J., Kommineni, C. V., and Roy, T. A. 1996. Light catalytically cracked naphtha: Subchronic toxicity of vapors in rats and mice and developmental toxicity screen in rats. J. Toxicol. Environ. Health 47:77-91.
18. Feuston, M. H., Low, L. K., Hamilton, C. E., and Mackerer, C. R. 1994. Correlation of systemic and developmental toxicities with chemical component classes of refinery streams. Fundam. Appl. Toxicol. 22:622-630.
19. Halder, C. A., Warne, T. M., and Hatoum, N. S. 1984. Renal toxicity of gasoline and related naphthas in male rats. In Renal effects of petroleum hydrocarbons, vol. 7, Advances in Modern Environmental Toxicology, eds. M. A. Mehlmann, C. P. Hemstreet III, J. J. Thorpe, and N. K. Weaver, pp. 73-88. Princeton, NJ: Princeton Scientific.
20. Halder, C. A., Van Gorp, G. S., Hatoum, N. S., and Warne, T. M. 1986. Gasoline vapor exposures Part 1. Characterization of workplace exposures. Am. Ind. Hyg. Assoc. J. 47:164-172.
21. Koschier, F. J., Burnett, D. M., Bui, Q. Q., Breglia, R. J., Lapadula, E. S., Podhasky, P. I., Schreiner, C. A., and White, R. D. 1996. Refinery stream and gasoline vapor generation methodology for toxicological evaluations. Toxicologist 30:108.
22. Organization for Economic Cooperation and Development. 1992. Guidelines for the Testing of Chemicals. Guideline No. 421: Reproduction/Developmental Toxicity Screening Test, Final Draft. Paris: OECD.
23. Roberts, L., Schroeder, R., Newton, P., White, R., Bui, Q., Koschier, F., Rodney, S., Schreiner, C., Steup, D., Breglia, R., and Rhoden, R. 1997. Developmental toxicity evaluation of unleaded gasoline vapor in the rat. Toxicologist 36:1316.