Analyses of signal transduction cascades in rat pinealocytes reveal a switch in cholinergic signaling during postnatal development

Brain Research

Volumn 833, Issue 1, 1999, Pages 39-50

  Schomerus, Christof ^a   Laedtke, Elke ^a   Korf, Horst Werner ^a  

^a Dr Senckenbergische Anatomie   (Germany)

Author keywords

Acetylcholine; Calcium; CREB; Norepinephrine; Ontogeny; Vasoactive intestinal peptide

Indexed keywords

ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CALCIUM; CALCIUM CHANNEL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MELATONIN; NICOTINIC RECEPTOR; NORADRENALIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; HORMONE SYNTHESIS; NONHUMAN; ONTOGENY; PINEALOCYTE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SYMPATHETIC INNERVATION;

ACETYLCHOLINE; AGING; ANIMALS; ANIMALS, NEWBORN; CALCIUM SIGNALING; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; MALE; NEUROPEPTIDES; NOREPINEPHRINE; PHOSPHORYLATION; PINEAL GLAND; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RECEPTORS, CHOLINERGIC; SIGNAL TRANSDUCTION; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0033606425     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01533-4     Document Type: Article

References (60)

1. Araki M., Tokunaga F. Norepinephrine suppresses both photoreceptor and neuron-like properties expressed by cultured rat pineal glands. Cell Differ. Dev. 31:1990;129-135.
2. Araki M., Watanabe K., Tokunaga F., Nonaka T. Phenotypic expression of photoreceptor and endocrine cell properties by cultured pineal cells of the newborn rat. Cell Differ. Dev. 25:1988;155-164.
3. J. Arendt, Melatonin and the Mammalian Pineal Gland, Chapman and Hall, London, 1995.
4. Ashkenazi A., Ramachandran J., Capon D.J. Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes. Nature. 340:1989;146-150.
5. D.A. Auerbach, β-Adrenergic receptors during development. In: D.C. Klein (Ed.), Melatonin Rhythm Generating System: Developmental Aspects. Karger, Basel, 1982, pp. 97-107.
6. Baler R., Covington S., Klein D.C. The rat arylalkylamine N-acetyltransferase gene promotor. J. Biol. Chem. 272:1997;6979-6985.
7. Berridge M.J. The AM and FM of calcium signalling. Nature. 386:1997;759-760.
8. Blackshaw S., Snyder S.H. Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function. J. Neurosci. 17:1997;8074-8082.
9. Borjigin J., Wang M.M., Snyder S.H. Diurnal variation in mRNA encoding serotonin-N-acetyltransferase in pineal gland. Nature. 378:1995;783-785.
10. Chik C.L., Ho A.K. Pituitary adenylate cyclase-activating polypeptide: control of rat pineal cyclic AMP and melatonin but not cyclic GMP. J. Neurochem. 64:1995;2111-2117.
11. Clapham D.E. Calcium signaling. Cell. 80:1995;259-268.
12. Coon S.L., Roseboom P.H., Baler R., Weller J.L., Namboodiri M.A.A., Koonin E.V., Klein D.C. Pineal serotonin-N-acetyltransferase: expression cloning and molecular analysis. Science. 270:1995;1681-1683.
13. Drijfhout W.J., Grol C.J., Westerink B.H.C. Parasympathetic inhibition of pineal indole metabolism by prejunctional modulation of noradrenergic release. Eur. J. Pharmacol. 308:1996;117-124.
14. Finocchiaro L.M.F., Scheucher A., Finkielman S., Nahmod V.E., Pirola C.J. Muscarinic effects on the hydroxy- and methoxyindole pathway in the rat pineal gland. J. Endocrinol. 123:1989;205-211.
15. Foulkes N.S., Borjigin J., Snyder S.H., Sassone-Corsi P. Transcriptional control of circadian hormone synthesis via the CREM feedback loop. Proc. Natl. Acad. Sci. USA. 93:1996;14140-14145.
16. Gastel J.A., Roseboom P.H., Rinaldi P.A., Weller J.L., Klein D.C. Melatonin production: proteosomal proteolysis in serotonin N-acetyltransferase regulation. Science. 279:1998;1358-1360.
17. Ginty D.D. Calcium regulation of gene expression: isn't that spatial? Neuron. 18:1997;183-186.
18. Gutkind J.S., Novotny E.A., Brann M.R., Robbins K.C. Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes. Proc. Natl. Acad. Sci. USA. 88:1991;4703-4707.
19. Hakanson R., Lombard des Gouttes M.N., Owman C. Activities of tryptophan hydroxylase, DOPA decarboxylase and monoamine oxidase as correlated with the appearance of monoamines in developing rat pineal gland. Life Sci. 6:1967;2577-2585.
20. Kaneko T., Cheng P.Y., Oka H., Oda T., Yanaihara N., Yanaihara C. Vasoactive intestinal polypeptide stimulates adenylate cyclase and serotonin N-acetyltransferase activities in rat pineal gland in vitro. Biomed. Res. 1:1980;84-87.
21. D.C. Klein, Photoneural regulation of the mammalian pineal gland. In: D. Evered, S. Clark (Eds.), Photoperiodism, Melatonin and the Pineal Gland. Ciba Foundation Symposium 117, Pitman, London, 1985, pp. 38-56.
22. Klein D.C., Roseboom P.H., Coon S.L. New light is shining on the melatonin rhythm enzyme. The first postcloning review. Trends Endocrinol. Metab. 7:1996;106-112.
23. Klein D.C., Coon S.L., Roseboom P.H., Weller J.L., Bernard M., Gastel J.A., Zatz M., Iuvone P.M., Rodriguez I.R., Bégay V., Falcón J., Cahill G.M., Cassone V.M., Baler R. The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland. Rec. Progr. Hormone Res. 52:1997;307-358.
24. Korf H.W. The pineal organ as a component of the biological clock. Ann. New York Acad. Sci. 719:1994;13-42.
25. Korf H.W., Møller M. The innervation of the mammalian pineal gland with special reference to central pinealopetal projections. Pineal Res. Rev. 2:1984;41-86.
26. Korf H.W., Møller M., Gery I., Zigler J.S., Klein D.C. Immunocytochemical demonstration of retinal S-antigen in the pineal organ of four mammalian species. Cell Tissue Res. 239:1985;81-85.
27. H.W. Korf, C. Schomerus, J.H. Stehle, The pineal organ, its hormone melatonin, and the photoneuroendocrine system, Adv. Anat. Embryol. Cell Biol., 146, Springer, Berlin, 1998, 100 pp.
28. C. Kramm, Photorezeptormerkmale in Netzhaut und Pinealorgan der Säugetiere unter besonderer Berücksichtigung des Differenzierungspotentials cerebellärer Medulloblastome des Menschen, Thesis, University of Frankfurt/M., 1993.
29. Laitinen J.T., Laitinen K.S.M., Kokkola T. Cholinergic signaling in the rat pineal gland. Cell. Mol. Neurobiol. 15:1995;177-192.
30. 2+ channels in rat pinealocytes. J. Physiol. 499:1997;329-340.
31. Meldolesi J. Oscillation, activation, expression. Nature. 392:1998;863-865.
32. Møller M. Fine structure of the pinealopetal innervation of the mammalian pineal gland. Microsc. Res. Tech. 21:1992;188-204.
33. Olcese J., McArdle C., Mikkelsen J., Hannibal J. PACAP and type I PACAP receptors in the pineal gland. Ann. New York Acad. Sci. 805:1996;595-600.
34. Pfeffer M., Stehle J.H. Ontogeny of a diurnal rhythm in arylalkylamine-N-acetyltransferase mRNA in rat pineal gland. Neurosci. Lett. 248:1998;163-166.
35. Roseboom P.H., Klein D.C. Norepinephrine stimulation of pineal cyclic AMP response element-binding protein phosphorylation: involvement of a β-adrenergic/cyclic AMP mechanism. Mol. Pharmacol. 47:1995;439-449.
36. Roseboom P.H., Coon S.L., Baler R., McCune S.K., Weller J.L., Klein D.C. Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland. Endocrinology. 137:1996;3033-3044.
37. i analysis and biochemical characterization of pinealocytes immobilized with novel attachment peptide preparation. Brain Res. 614:1993;251-256.
38. Schaad N.C., Vanecek J., Rodriguez I.R., Klein D.C., Holtzclaw L., Russell J.T. Vasoactive intestinal peptide elevates pinealocyte intracellular calcium concentrations by enhancing influx: evidence for involvement of a cyclic GMP-dependent mechanism. Mol. Pharmacol. 47:1995;923-933.
39. Schäfer M.K.H., Eiden L.E., Weihe E. Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter: I. Central nervous system. Neuroscience. 84:1998;331-359.
40. Schlumpf M., Bruinink A., Lichtensteiger W., Cortés R., Palacios J.M., Pazos A. Beta adrenergic binding sites in fetal rat central nervous system and pineal gland: their relation to other receptor sites. Dev. Pharmacol. Ther. 10:1987;422-435.
41. Schlumpf M., Palacios J.M., Cortés R., Lichtensteiger W. Regional development of muscarinic cholinergic binding sites in the prenatal rat brain. Neuroscience. 45:1991;347-357.
42. Schomerus C., Ruth P., Korf H.W. Photoreceptor-specific proteins in the mammalian pineal organ: immunocytochemical data and functional considerations. Acta Neurobiol. Exp. 54(Suppl.):1994;9-17.
43. Schomerus C., Laedtke E., Korf H.W. Calcium responses of isolated, immunocytochemically identified rat pinealocytes to noradrenergic, cholinergic and vasopressinergic stimulations. Neurochem. Int. 27:1995;163-175.
44. Schomerus C., Maronde E., Laedtke E., Korf H.W. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) induce phosphorylation of the transcriptional factor CREB in subpopulations of rat pinealocytes: immunocytochemical and immunochemical evidence. Cell Tissue Res. 286:1996;305-313.
45. Simonneaux V., Ouichou A., Pévet P. Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates melatonin synthesis from the rat pineal gland. Brain Res. 603:1993;148-152.
46. Stehle J.H., Foulkes N.S., Molina C.A., Simonneaux V., Pévet P., Sassone-Corsi P. Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland. Nature. 356:1993;314-320.
47. Stehle J.H., Foulkes N.S., Pévet P., Sassone-Corsi P. Developmental maturation of pineal gland function: synchronized CREM inducibility and adrenergic stimulation. Mol. Endocrinol. 9:1995;706-716.
48. Tamarkin L., Reppert S.M., Orloff D.J., Klein D.C., Yellon S.M., Goldman B.D. Ontogeny of the pineal melatonin rhythm in the Syrian (Mesocricetus auratus) and Siberian (Phodopus sungorus) hamsters and in the rat. Endocrinology. 107:1980;1061-1064.
49. Tamotsu S., Schomerus C., Stehle J.H., Roseboom P.H., Korf H.W. Norepinephrine-induced phosphorylation of the transcription factor CREB in isolated rat pinealocytes: an immunocytochemical study. Cell Tissue Res. 282:1995;219-226.
50. Taylor R.L., Albuquerque M.L.C., Burt D.R. Muscarinic receptors in pineal. Life Sci. 26:1980;2195-2200.
51. 1-regulations of adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate in rat pinealocytes. Endocrinology. 116:1985;2167-2173.
52. L. Vollrath, The pineal organ. In: A. Oksche, L. Vollrath (Eds.), Handbuch der Mikroskopischen Anatomie des Menschen, Vol. VI/7, Springer, Berlin, 1981.
53. Wessler I., Reinheimer T., Bittinger F., Kirkpatrick C.J., Schenda J., Vollrath L. Day-night rhythm of acetylcholine in the rat pineal gland. Neurosci. Lett. 224:1997;173-176.
54. 2+: possible involvement of a diffusible factor. Endocrinology. 132:1993;1026-1034.
55. Wicht H., Maronde E., Olcese J., Korf H.W. A semiquantitative image-analytical method for the recording of dose-response curves in immunocytochemical preparations. J. Histochem. Cytochem. 47:1999;411-419.
56. i during cell division and differentiation in the mammalian retina. J. Neurosci. 15:1995;2696-2705.
57. Yamada H., Ogura A., Koizumi S., Yamaguchi A., Moriyama Y. Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes. J. Neurosci. 18:1998;4946-4952.
58. Yamashita M., Fukuda Y. Incurvation of early embryonic neural retina by acetylcholine through muscarinic receptors. Neurosci. Lett. 163:1993;215-218.
59. Yuwiler A. Vasoactive intestinal peptide stimulation of pineal serotonin-N-acetyltransferase activity: general characteristics. J. Neurochem. 41:1983;146-153.
60. Yuwiler A., Klein D.C., Buda M., Weller J.L. Adrenergic control of pineal N-acetyltransferase activity: developmental aspects. Am. J. Physiol. 233:1977;E141-146.