-
1
-
-
0031924992
-
Reactions of 4-hydroxy-2 (E)-nonenal and related aldehydes with proteins studied by carbon-13 nuclear magnetic resonance spectroscopy
-
Amarnath, V., Valentine, W. M., Montine, T. J., Patterson, W. H., Amarnath, K., Bassett, C. N., and Graham, D. G. 1998. Reactions of 4-hydroxy-2 (E)-nonenal and related aldehydes with proteins studied by carbon-13 nuclear magnetic resonance spectroscopy. Chem. Res. Toxicol. 11:317-328.
-
(1998)
Chem. Res. Toxicol.
, vol.11
, pp. 317-328
-
-
Amarnath, V.1
Valentine, W.M.2
Montine, T.J.3
Patterson, W.H.4
Amarnath, K.5
Bassett, C.N.6
Graham, D.G.7
-
2
-
-
0024514216
-
Effect of cyclophosphamide on the immature rat ovary
-
Ataya, K. M., Valeriote, F. A., and Ramahi-Ataya, A. J. 1989. Effect of cyclophosphamide on the immature rat ovary. Cancer Res. 49:1660-1664.
-
(1989)
Cancer Res.
, vol.49
, pp. 1660-1664
-
-
Ataya, K.M.1
Valeriote, F.A.2
Ramahi-Ataya, A.J.3
-
3
-
-
0018653948
-
Relationships between sister chromatid exchange and mutagenicity, toxicity and DNA damage
-
Bradley, M. O., Hsu, I. C., and Harris, C. C. 1979. Relationships between sister chromatid exchange and mutagenicity, toxicity and DNA damage. Nature 282:318-320.
-
(1979)
Nature
, vol.282
, pp. 318-320
-
-
Bradley, M.O.1
Hsu, I.C.2
Harris, C.C.3
-
4
-
-
0024577791
-
Covalent binding of inhaled formaldehyde to DNA in the nasal mucosa of Fischer 344 rats: Analysis of formaldehyde and DNA by high-performance liquid chromatography and provisional pharmacokinetic interpretation
-
Casanova, M., Deyo, D. F., and Heck, H. d'A. 1989. Covalent binding of inhaled formaldehyde to DNA in the nasal mucosa of Fischer 344 rats: Analysis of formaldehyde and DNA by high-performance liquid chromatography and provisional pharmacokinetic interpretation. Fundam. Appl. Toxicol. 12:397-417.
-
(1989)
Fundam. Appl. Toxicol.
, vol.12
, pp. 397-417
-
-
Casanova, M.1
Deyo, D.F.2
Heck, H.D'A.3
-
5
-
-
0025823449
-
Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: Pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man
-
Casanova, M., Morgan, K. T., Steinhagen, W. H., Everitt, J. I., Popp, J. A., and Heck, H. d'A. 1991. Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: Pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man. Fundam. Appl. Toxicol. 17:409-428.
-
(1991)
Fundam. Appl. Toxicol.
, vol.17
, pp. 409-428
-
-
Casanova, M.1
Morgan, K.T.2
Steinhagen, W.H.3
Everitt, J.I.4
Popp, J.A.5
Heck, H.D'A.6
-
6
-
-
77957183484
-
DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde
-
Casanova, M., Morgan, K. T., Gross, E. A., Moss, O. R., and Heck, H. d'A. 1994. DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde. Fundam. Appl. Toxicol. 23:525-536.
-
(1994)
Fundam. Appl. Toxicol.
, vol.23
, pp. 525-536
-
-
Casanova, M.1
Morgan, K.T.2
Gross, E.A.3
Moss, O.R.4
Heck, H.D'A.5
-
7
-
-
26844477264
-
1 mice but not Syrian golden hamsters exposed to dichloromethane: Pharmacokinetics and risk assessment with DPX as dosimeter
-
1 mice but not Syrian golden hamsters exposed to dichloromethane: Pharmacokinetics and risk assessment with DPX as dosimeter. Fundam. Appl. Toxicol. 31:103-116.
-
(1996)
Fundam. Appl. Toxicol.
, vol.31
, pp. 103-116
-
-
Casanova, M.1
Conolly, R.B.2
Heck, H.D'A.3
-
8
-
-
0029791186
-
Comments of "DNA-protein crosslinks, a biomarker of exposure to formaldehyde-in vitro and in vivo studies" by Shaham et al
-
Casanova, M., Heck, H. D'A., and Janszen, D. 1996b. Comments of "DNA-protein crosslinks, a biomarker of exposure to formaldehyde-in vitro and in vivo studies" by Shaham et al. Carcinogenesis 17:2097-2101.
-
(1996)
Carcinogenesis
, vol.17
, pp. 2097-2101
-
-
Casanova, M.1
Heck, H.D'A.2
Janszen, D.3
-
9
-
-
0019985441
-
Nickel distribution and DNA lesions induced in rat tissues by the carcinogen nickel carbonate
-
Ciccarelli, R. B., and Wetterhahn, K. E. 1982. Nickel distribution and DNA lesions induced in rat tissues by the carcinogen nickel carbonate. Cancer Res. 42:3544-3549.
-
(1982)
Cancer Res.
, vol.42
, pp. 3544-3549
-
-
Ciccarelli, R.B.1
Wetterhahn, K.E.2
-
10
-
-
0023761371
-
Growth inhibition and DNA damage induced by benzo[a]pyrene and formaldehyde in primary cultures of rat tracheal epithelial cells
-
Cosma, G. N., Jamasbi, R., and Marchok, A. C. 1988. Growth inhibition and DNA damage induced by benzo[a]pyrene and formaldehyde in primary cultures of rat tracheal epithelial cells. Mutat. Res. 201:161-168.
-
(1988)
Mutat. Res.
, vol.201
, pp. 161-168
-
-
Cosma, G.N.1
Jamasbi, R.2
Marchok, A.C.3
-
11
-
-
0027405941
-
DNA-protein cross-links in welders: Molecular implications
-
Costa, M., Zhitkovich, A., and Toniolo, P. 1993. DNA-protein cross-links in welders: Molecular implications. Cancer Res. 53:460-463.
-
(1993)
Cancer Res.
, vol.53
, pp. 460-463
-
-
Costa, M.1
Zhitkovich, A.2
Toniolo, P.3
-
12
-
-
0029947856
-
Interlaboratory validation of a new assay for DNA-protein crosslinks
-
Costa, M., Zhitkovich, A., Gargas, M., Paustenbach, D., Finley, B., Kuykendall, J., Billings, R., Carlson, T. J., Wetterhahn, K., Xu, J., Patierno, S., and Bogdanffy, M. 1996. Interlaboratory validation of a new assay for DNA-protein crosslinks. Mutat. Res. 369:13-21.
-
(1996)
Mutat. Res.
, vol.369
, pp. 13-21
-
-
Costa, M.1
Zhitkovich, A.2
Gargas, M.3
Paustenbach, D.4
Finley, B.5
Kuykendall, J.6
Billings, R.7
Carlson, T.J.8
Wetterhahn, K.9
Xu, J.10
Patierno, S.11
Bogdanffy, M.12
-
13
-
-
0022452407
-
Cytotoxicity, DNA cross-linking, and single strand breaks induced by activated cyclophosphamide and acrolein in human leukemia cells
-
Crook, T. R., Souhami, R. L., and McLean, A. E. M. 1986. Cytotoxicity, DNA cross-linking, and single strand breaks induced by activated cyclophosphamide and acrolein in human leukemia cells. Cancer Res. 46:5029-5034.
-
(1986)
Cancer Res.
, vol.46
, pp. 5029-5034
-
-
Crook, T.R.1
Souhami, R.L.2
McLean, A.E.M.3
-
14
-
-
0023815322
-
Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo
-
DeNeve, W. J., Everett, C. K., Suminski, J. E., and Valeriote, F. A. 1988. Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo. Cancer Res. 48:6002-6005.
-
(1988)
Cancer Res.
, vol.48
, pp. 6002-6005
-
-
DeNeve, W.J.1
Everett, C.K.2
Suminski, J.E.3
Valeriote, F.A.4
-
15
-
-
0024312087
-
In vivo cross-linking by cyclophosphamide: Comparisons of human chronic lymphatic leukemia cells with mouse L1210 leukemia and normal bone marrow cells
-
DeNeve, W., Valeriote, F., Edelstein, M., Everett, C., and Bischoff, M. (1989). In vivo cross-linking by cyclophosphamide: comparisons of human chronic lymphatic leukemia cells with mouse L1210 leukemia and normal bone marrow cells. Cancer Res. 49:3452-3456.
-
(1989)
Cancer Res.
, vol.49
, pp. 3452-3456
-
-
DeNeve, W.1
Valeriote, F.2
Edelstein, M.3
Everett, C.4
Bischoff, M.5
-
16
-
-
0021932501
-
Interactions of mitomycin C with mammalian DNA detected by alkaline elution
-
Dorr, R. T., Bowden, T., Alberts, D. S., and Liddil, J. D. 1985. Interactions of mitomycin C with mammalian DNA detected by alkaline elution. Cancer Res. 45:3510-3516.
-
(1985)
Cancer Res.
, vol.45
, pp. 3510-3516
-
-
Dorr, R.T.1
Bowden, T.2
Alberts, D.S.3
Liddil, J.D.4
-
17
-
-
0020043230
-
Detection of single-stranded breaks produced during the repair of damage by DNA-protein cross-linking agents
-
Fornace, A. J. 1982. Detection of single-stranded breaks produced during the repair of damage by DNA-protein cross-linking agents. Cancer Res. 42:145-149.
-
(1982)
Cancer Res.
, vol.42
, pp. 145-149
-
-
Fornace, A.J.1
-
18
-
-
0019133937
-
Malignant transformation by the DNA-protein crosslinking agent trans-Pt(II) diamminedichloride
-
Fornace, A. J., and Little, J. B. 1980. Malignant transformation by the DNA-protein crosslinking agent trans-Pt(II) diamminedichloride. Carcinogenesis 1:989-994.
-
(1980)
Carcinogenesis
, vol.1
, pp. 989-994
-
-
Fornace, A.J.1
Little, J.B.2
-
19
-
-
0004939427
-
Inhibition of topoisomerase II by benzene in vivo and benzene metabolites in vitro: A potential mechanism of benzene-induced leukemogenesis
-
Frantz, C. E., and Eastmond, D. A. 1998. Inhibition of topoisomerase II by benzene in vivo and benzene metabolites in vitro: A potential mechanism of benzene-induced leukemogenesis. Toxicologist Toxicol. Sci. Suppl. 42:184-185.
-
(1998)
Toxicologist Toxicol. Sci. Suppl.
, vol.42
, pp. 184-185
-
-
Frantz, C.E.1
Eastmond, D.A.2
-
20
-
-
0030446664
-
Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites
-
abstr.
-
Frantz, C. E., Chen, H., and Eastmond, D. A. 1996. Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites. Environ. Health Perspect. 104(Suppl. 6):1319-1324 (abstr.).
-
(1996)
Environ. Health Perspect.
, vol.104
, Issue.6 SUPPL.
, pp. 1319-1324
-
-
Frantz, C.E.1
Chen, H.2
Eastmond, D.A.3
-
21
-
-
0017568045
-
Hematotoxicity in humans
-
Goldstein, B. D. 1977. Hematotoxicity in humans. J. Toxicol. Environ. Health (Suppl.) 2:69-105.
-
(1977)
J. Toxicol. Environ. Health
, vol.2
, Issue.SUPPL.
, pp. 69-105
-
-
Goldstein, B.D.1
-
22
-
-
0019762730
-
Muconaldehyde, a potential toxic intermediate of benzene metabolism
-
eds. R. Snyder, D. V. Parke, J. J. Kocsis, J. Jallow, G. G. Gibson, and C. M. Witmer, New York: Plenum Press
-
Goldstein, B. D., Witz, G., Javid, J., Amoruso, M., Rossman, T., and Wolder, B. 1982. Muconaldehyde, a potential toxic intermediate of benzene metabolism. In Biological reactive intermediates, eds. R. Snyder, D. V. Parke, J. J. Kocsis, J. Jallow, G. G. Gibson, and C. M. Witmer, vol. 2, pp. 331-339. New York: Plenum Press.
-
(1982)
Biological Reactive Intermediates
, vol.2
, pp. 331-339
-
-
Goldstein, B.D.1
Witz, G.2
Javid, J.3
Amoruso, M.4
Rossman, T.5
Wolder, B.6
-
23
-
-
0004427238
-
Benzene
-
ed. M. Lipman, New York: Van Nostrand Reinhold
-
Goldstein, B. D., and Witz, G. 1992. Benzene. In Environmental toxicants, human exposure and their health effects, ed. M. Lipman, pp. 76-97. New York: Van Nostrand Reinhold.
-
(1992)
Environmental Toxicants, Human Exposure and Their Health Effects
, pp. 76-97
-
-
Goldstein, B.D.1
Witz, G.2
-
24
-
-
0027216713
-
Metabolism and cytotoxicity of trans,trans-muconaldehyde and its derivatives: Potential markers of benzene ring cleavage reactions
-
Goon, D., Matsuura, J., and Ross, D. 1993. Metabolism and cytotoxicity of trans,trans-muconaldehyde and its derivatives: Potential markers of benzene ring cleavage reactions. Chem. Biol. Interact. 88:37-53.
-
(1993)
Chem. Biol. Interact.
, vol.88
, pp. 37-53
-
-
Goon, D.1
Matsuura, J.2
Ross, D.3
-
25
-
-
0021177232
-
Repair of DNA damage caused by form-aldehyde in human cells
-
Grafstrom, R. C., Fornace, A., Jr., and Harris, C. C. 1984. Repair of DNA damage caused by form-aldehyde in human cells. Cancer Res. 44:4323-4327.
-
(1984)
Cancer Res.
, vol.44
, pp. 4323-4327
-
-
Grafstrom, R.C.1
Fornace Jr., A.2
Harris, C.C.3
-
26
-
-
0023234707
-
Formation and removal of DNA-cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells
-
Hansson, J., Lewensohn, R., Ringborg, U., and Nilsson B. 1987. Formation and removal of DNA-cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells. Cancer Res. 47:2631-2637.
-
(1987)
Cancer Res.
, vol.47
, pp. 2631-2637
-
-
Hansson, J.1
Lewensohn, R.2
Ringborg, U.3
Nilsson, B.4
-
27
-
-
84969033199
-
The formation of DNA-protein cross-links by aldehydes present in tobacco smoke
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
-
Heck, H. D'A., Casanova, M., Lam, C.-W., and Swenberg, J. A. 1986. The formation of DNA-protein cross-links by aldehydes present in tobacco smoke. Banbury Report 23, Mechanisms in Tobacco Carcinogenesis, pp. 215-230. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
-
(1986)
Banbury Report 23, Mechanisms in Tobacco Carcinogenesis
, pp. 215-230
-
-
Heck, H.D'A.1
Casanova, M.2
Lam, C.-W.3
Swenberg, J.A.4
-
28
-
-
0026731906
-
DNA strand breaks and DNA crosslinks in peripheral mononuclear blood cells of ovarian cancer patients during chemotherapy with cyclophosphamide/carboplatin
-
Hengstler, J. G., Fuchs, J., and Oesch, F. 1992. DNA strand breaks and DNA crosslinks in peripheral mononuclear blood cells of ovarian cancer patients during chemotherapy with cyclophosphamide/carboplatin. Cancer Res. 52:5622-5626.
-
(1992)
Cancer Res.
, vol.52
, pp. 5622-5626
-
-
Hengstler, J.G.1
Fuchs, J.2
Oesch, F.3
-
29
-
-
0025679117
-
In vitro studies on the mechanism of action of hepsulfam in chronic myelogenous leukemia patients
-
Hincks, J. R., Adlakha, A., Cook, C. A., Johnson, C. S., Furmanski, P., and Gibson, N. W. 1990. In vitro studies on the mechanism of action of hepsulfam in chronic myelogenous leukemia patients. Cancer Res. 50:7559-7563.
-
(1990)
Cancer Res.
, vol.50
, pp. 7559-7563
-
-
Hincks, J.R.1
Adlakha, A.2
Cook, C.A.3
Johnson, C.S.4
Furmanski, P.5
Gibson, N.W.6
-
30
-
-
0030445214
-
Inhibition of human DNA topoisomerase I by hydroquinone and p-benzoquinone, reactive metabolites of benzene
-
Hutt, A. M., and Kalf, G. F. 1996. Inhibition of human DNA topoisomerase I by hydroquinone and p-benzoquinone, reactive metabolites of benzene. Environ. Health Perspect. 104(Suppl. 6):1265-1269.
-
(1996)
Environ. Health Perspect.
, vol.104
, Issue.6 SUPPL.
, pp. 1265-1269
-
-
Hutt, A.M.1
Kalf, G.F.2
-
31
-
-
0018933403
-
Effects of the principal hydroxymetabolites of benzene on microtubule polymerization
-
Irons, R. D., and Neptun, D. A. 1980. Effects of the principal hydroxymetabolites of benzene on microtubule polymerization. Arch. Toxicol. 45:297-305.
-
(1980)
Arch. Toxicol.
, vol.45
, pp. 297-305
-
-
Irons, R.D.1
Neptun, D.A.2
-
32
-
-
0024449143
-
Prevention of benzene-induced myelotoxicity by nonsteroidal anti-inflammatory drugs
-
Kalf, G. F., Schlosser, M. J., Renz, J. F., and Pirozzi, S. J. 1989. Prevention of benzene-induced myelotoxicity by nonsteroidal anti-inflammatory drugs. Environ. Health Perspect. 82:57-64.
-
(1989)
Environ. Health Perspect.
, vol.82
, pp. 57-64
-
-
Kalf, G.F.1
Schlosser, M.J.2
Renz, J.F.3
Pirozzi, S.J.4
-
33
-
-
0027892521
-
Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
-
Kamesaki, S., Kamesaki, H., Jorgensen, T.J., Tanizawa, A., Pommier, Y., and Cossman, J. 1993. Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res. 53:4251-4256.
-
(1993)
Cancer Res.
, vol.53
, pp. 4251-4256
-
-
Kamesaki, S.1
Kamesaki, H.2
Jorgensen, T.J.3
Tanizawa, A.4
Pommier, Y.5
Cossman, J.6
-
34
-
-
0027250844
-
Reaction of (E,E)-muconaldehyde and its aldehydic metabolites, (E,E)-6-oxohexadienoic acid and (E,E)-6-hydroxyhexa-2,4-dienal, with glutathione
-
Kline, S. A., Xiang, Q., Goldstein, B. D., and Witz, G. 1993. Reaction of (E,E)-muconaldehyde and its aldehydic metabolites, (E,E)-6-oxohexadienoic acid and (E,E)-6-hydroxyhexa-2,4-dienal, with glutathione. Chem. Res. Toxicol. 6:578-583.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 578-583
-
-
Kline, S.A.1
Xiang, Q.2
Goldstein, B.D.3
Witz, G.4
-
35
-
-
0027408743
-
Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo
-
Kolachana, P., Subrahmanyam, V. V., Meyer, K. B., Zhang, L., and Smith, M. T. 1993. Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo. Cancer Res. 53:1023-1026.
-
(1993)
Cancer Res.
, vol.53
, pp. 1023-1026
-
-
Kolachana, P.1
Subrahmanyam, V.V.2
Meyer, K.B.3
Zhang, L.4
Smith, M.T.5
-
36
-
-
0027453767
-
Cytotoxicity and DNA-protein crosslink formation in rat nasal tissues exposed to vinyl acetate are carboxylesterase-mediated
-
Kuykendall, J. R., Taylor, M. L., and Bogdanffy, M. S. 1993. Cytotoxicity and DNA-protein crosslink formation in rat nasal tissues exposed to vinyl acetate are carboxylesterase-mediated. Toxicol. Appl. Pharmacol. 123:283-292.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.123
, pp. 283-292
-
-
Kuykendall, J.R.1
Taylor, M.L.2
Bogdanffy, M.S.3
-
37
-
-
0028997789
-
DNA-protein crosslink formation in rat nasal epithelial cells by hexamethylphosphoramide and its correlation with formaldehyde production
-
Kuykendall, J. R., Trela, B. A, and Bogdanffy, M. S. 1995. DNA-protein crosslink formation in rat nasal epithelial cells by hexamethylphosphoramide and its correlation with formaldehyde production. Mutat. Res. 343:209-218.
-
(1995)
Mutat. Res.
, vol.343
, pp. 209-218
-
-
Kuykendall, J.R.1
Trela, B.A.2
Bogdanffy, M.S.3
-
38
-
-
0022401545
-
Depletion of nasal mucosal glutathione by acrolein and enhancement of formaldehyde-induced DNA-protein cross-linking by simultaneous exposure to acrolein
-
Lam, C.-W., Casanova, M., and Heck, H. d'A. 1985. Depletion of nasal mucosal glutathione by acrolein and enhancement of formaldehyde-induced DNA-protein cross-linking by simultaneous exposure to acrolein. Arch. Toxicol. 58:67-71.
-
(1985)
Arch. Toxicol.
, vol.58
, pp. 67-71
-
-
Lam, C.-W.1
Casanova, M.2
Heck, H.D'A.3
-
40
-
-
0023230619
-
DNA cross-linking and single-strand breaks induced by teratogenic concentrations of 4-hydroperoxycyclophosphamide and phosphoramide mustard in post-implantation rat embryos
-
Little, S. A., and Mirkes, P. E. 1987. DNA cross-linking and single-strand breaks induced by teratogenic concentrations of 4-hydroperoxycyclophosphamide and phosphoramide mustard in post-implantation rat embryos. Cancer Res. 47:5421-5426.
-
(1987)
Cancer Res.
, vol.47
, pp. 5421-5426
-
-
Little, S.A.1
Mirkes, P.E.2
-
41
-
-
0023881799
-
Review of the genotoxicity of formaldehyde
-
Ma, T.-H., and Harris, M. M. 1988. Review of the genotoxicity of formaldehyde. Mutat. Res. 196:37-59.
-
(1988)
Mutat. Res.
, vol.196
, pp. 37-59
-
-
Ma, T.-H.1
Harris, M.M.2
-
42
-
-
0023181174
-
Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210
-
Markovits, J., Pommier, Y., Kerrigan, D., Covey, J. M., Tilchen, E. J., and Kohn, K. W. 1987. Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210. Cancer Res. 47:2050-2055.
-
(1987)
Cancer Res.
, vol.47
, pp. 2050-2055
-
-
Markovits, J.1
Pommier, Y.2
Kerrigan, D.3
Covey, J.M.4
Tilchen, E.J.5
Kohn, K.W.6
-
43
-
-
0019556071
-
Predominance of core histones in formation of DNA-protein cross-links in γ-irradiated chromatin
-
Mee, L. K., and Adelstein, S. I. 1981. Predominance of core histones in formation of DNA-protein cross-links in γ-irradiated chromatin. Proc. Natl. Acad. Sci. USA 78:2194-2198.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 2194-2198
-
-
Mee, L.K.1
Adelstein, S.I.2
-
44
-
-
0027458459
-
Enhancement by L-histidine of nickel(II)-induced DNA-protein cross-linking and oxidative DNA base damage in the rat kidney
-
Misra, M., Olinski, R., Dizdaroglu, M., and Kasprzak, K. S. 1993. Enhancement by L-histidine of nickel(II)-induced DNA-protein cross-linking and oxidative DNA base damage in the rat kidney. Chem. Res. Toxicol. 6:33-37.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 33-37
-
-
Misra, M.1
Olinski, R.2
Dizdaroglu, M.3
Kasprzak, K.S.4
-
45
-
-
0019816225
-
Irreparable DNA crosslinks and mammalian cell lethality with bifunctional alkylating agents
-
Murnane, J. P., and Byfield, J. E. 1981. Irreparable DNA crosslinks and mammalian cell lethality with bifunctional alkylating agents. Chem. Biol. Interact. 38:75-86.
-
(1981)
Chem. Biol. Interact.
, vol.38
, pp. 75-86
-
-
Murnane, J.P.1
Byfield, J.E.2
-
46
-
-
0022356919
-
Kinetics of DNA cross-linking in normal and neoplastic mouse tissues following treatment with cis-diamminedichloroplatinum(II) in vivo
-
Murray, D., Jenkins, W. T., and Meyn, R. E. 1985. Kinetics of DNA cross-linking in normal and neoplastic mouse tissues following treatment with cis-diamminedichloroplatinum(II) in vivo. Cancer Res. 45:6446-6452.
-
(1985)
Cancer Res.
, vol.45
, pp. 6446-6452
-
-
Murray, D.1
Jenkins, W.T.2
Meyn, R.E.3
-
47
-
-
0028897831
-
Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonal
-
Nadkarni, D. V., and Sayre, L. M. 1995. Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonal. Chem. Res. Toxicol. 8:284-291.
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 284-291
-
-
Nadkarni, D.V.1
Sayre, L.M.2
-
48
-
-
0003633755
-
-
U.S. Department of Health and Human Services, Public Health Service, NIH Publication 86-23, Bethesda, MD
-
National Institutes of Health. 1995. Guide for the Care and Use of Laboratory Animals. U.S. Department of Health and Human Services, Public Health Service, NIH Publication 86-23, Bethesda, MD.
-
(1995)
Guide for the Care and Use of Laboratory Animals
-
-
-
49
-
-
0023224875
-
The formation, identification, and significance of DNA-protein cross-links in mammalian cells
-
Oleinick, N. L., Chiu, S., Ramakrishnan, N., and Xue, L. 1987. The formation, identification, and significance of DNA-protein cross-links in mammalian cells. Br. J. Cancer. 55(Suppl. VIII):135-140.
-
(1987)
Br. J. Cancer.
, vol.55
, Issue.8 SUPPL.
, pp. 135-140
-
-
Oleinick, N.L.1
Chiu, S.2
Ramakrishnan, N.3
Xue, L.4
-
50
-
-
0023151918
-
In vivo DNA-protein cross-linking by cis- and trans-diamminedichloroplatinum(II)
-
Olinski, R., Wedrychowski, A., Schmidt, W. N., Briggs, R. C., and Hnilca, L. S. 1987. In vivo DNA-protein cross-linking by cis-and trans-diamminedichloroplatinum(II). Cancer Res. 47:201-205.
-
(1987)
Cancer Res.
, vol.47
, pp. 201-205
-
-
Olinski, R.1
Wedrychowski, A.2
Schmidt, W.N.3
Briggs, R.C.4
Hnilca, L.S.5
-
51
-
-
0024434447
-
Comparison of the mechanism of action of busulfan with hepsulfam, a new antileukemic agent, in the L1210 cell line
-
Pacheco, D. Y., Stratton, N. K., and Gibson, N. W. 1989. Comparison of the mechanism of action of busulfan with hepsulfam, a new antileukemic agent, in the L1210 cell line. Cancer Res. 49: 5108-5110.
-
(1989)
Cancer Res.
, vol.49
, pp. 5108-5110
-
-
Pacheco, D.Y.1
Stratton, N.K.2
Gibson, N.W.3
-
52
-
-
0025678862
-
Mechanisms of toxicity of hepsulfam in human tumor cell lines
-
Pacheco, D. Y., Cook, C., Hincks, J. R., and Gibson, N. W. 1990. Mechanisms of toxicity of hepsulfam in human tumor cell lines. Cancer Res. 50:7555-7558.
-
(1990)
Cancer Res.
, vol.50
, pp. 7555-7558
-
-
Pacheco, D.Y.1
Cook, C.2
Hincks, J.R.3
Gibson, N.W.4
-
53
-
-
0025046596
-
Chromosome aberrations and prognostic factors in therapy-related myelodysplasia and acute nonlymphocytic leukemia
-
Pedersen-Bjergaard, J., Philip, P., Larsens, S. O., Jensen, G., and Byrsting, K. 1990. Chromosome aberrations and prognostic factors in therapy-related myelodysplasia and acute nonlymphocytic leukemia. Blood 76:1083-1091.
-
(1990)
Blood
, vol.76
, pp. 1083-1091
-
-
Pedersen-Bjergaard, J.1
Philip, P.2
Larsens, S.O.3
Jensen, G.4
Byrsting, K.5
-
54
-
-
0026544158
-
Radiotherapy- and chemotherapy-induced myelodysplasia and acute myeloid leukemia. A review
-
Pedersen-Bjergaard, J. 1992. Radiotherapy-and chemotherapy-induced myelodysplasia and acute myeloid leukemia. A review. Leukemia Res. 16:61-65.
-
(1992)
Leukemia Res.
, vol.16
, pp. 61-65
-
-
Pedersen-Bjergaard, J.1
-
55
-
-
0021050765
-
Alteration of lymphocyte function by quinones through sulfhydryl-dependent disruption of microtubule assembly
-
Pfeifer, R. W., and Irons, R. D. 1983. Alteration of lymphocyte function by quinones through sulfhydryl-dependent disruption of microtubule assembly. Int. J. Immunopharmacol. 5:463-470.
-
(1983)
Int. J. Immunopharmacol.
, vol.5
, pp. 463-470
-
-
Pfeifer, R.W.1
Irons, R.D.2
-
56
-
-
0028567148
-
DNA-protein cross-links and sister chromatid exchange frequencies in lymphocytes and hydroxyethyl mercapturic acid in urine of ethylene oxide-exposed hospital workers
-
Popp, W., Vahrenholz, C., Przygoda, H., Brauksiepe, A., Goch, S., Müller, G., Schnell, C., and Norpoth, K. 1994. DNA-protein cross-links and sister chromatid exchange frequencies in lymphocytes and hydroxyethyl mercapturic acid in urine of ethylene oxide-exposed hospital workers. Int. Arch. Occup. Environ. Health. 66:325-332.
-
(1994)
Int. Arch. Occup. Environ. Health.
, vol.66
, pp. 325-332
-
-
Popp, W.1
Vahrenholz, C.2
Przygoda, H.3
Brauksiepe, A.4
Goch, S.5
Müller, G.6
Schnell, C.7
Norpoth, K.8
-
57
-
-
0023279106
-
Yield of DNA-protein crosslinks in gamma irradiated Chinese hamster cells
-
Ramakrishnan, N., Song-Mao, C., and Jones, C. A. 1987. Yield of DNA-protein crosslinks in gamma irradiated Chinese hamster cells. Cancer Res. 47:2032-2035.
-
(1987)
Cancer Res.
, vol.47
, pp. 2032-2035
-
-
Ramakrishnan, N.1
Song-Mao, C.2
Jones, C.A.3
-
58
-
-
0019388119
-
Differential cytotoxicity and DNA cross-linking produced by polymeric and monomeric activated analogues of cyclophosphamide in mouse L1210 leukemia cells
-
Ramonas, L. M., Erickson, L. C., Klesse, W., Kohn, K. W., and Zaharko, D. S. 1981. Differential cytotoxicity and DNA cross-linking produced by polymeric and monomeric activated analogues of cyclophosphamide in mouse L1210 leukemia cells. Mol. Pharmacol. 19:331-336.
-
(1981)
Mol. Pharmacol.
, vol.19
, pp. 331-336
-
-
Ramonas, L.M.1
Erickson, L.C.2
Klesse, W.3
Kohn, K.W.4
Zaharko, D.S.5
-
59
-
-
0025267320
-
Formation and repair of DNA lesions in kidneys of male mice after acute exposure to methyl chloride
-
Ristau, C., Bolt, H. M., and Vangala, R. R. 1990. Formation and repair of DNA lesions in kidneys of male mice after acute exposure to methyl chloride. Arch. Toxicol. 64:254-256.
-
(1990)
Arch. Toxicol.
, vol.64
, pp. 254-256
-
-
Ristau, C.1
Bolt, H.M.2
Vangala, R.R.3
-
60
-
-
0004954826
-
The binding of trans,trans-muconaldehyde to deoxyguanosine and calf thymus DNA
-
Schatz-Kornbrust, E., Goldstein, B. D., and Witz, G. 1991. The binding of trans,trans-muconaldehyde to deoxyguanosine and calf thymus DNA. Toxicologist 11:61.
-
(1991)
Toxicologist
, vol.11
, pp. 61
-
-
Schatz-Kornbrust, E.1
Goldstein, B.D.2
Witz, G.3
-
61
-
-
74049096137
-
Mechanistic studies on benzene toxicity: Formation of DNA-protein crosslinks induced by benzene in mice and muconaldehyde in HL60 cells
-
abstr.
-
Schoenfeld, H. A., Radbourne, R., Goldstein, B. D., and Witz, G. 1996. Mechanistic studies on benzene toxicity: Formation of DNA-protein crosslinks induced by benzene in mice and muconaldehyde in HL60 cells. Toxicologist Toxicol. Appl. Pharmacol. Suppl. 30:232 (abstr.).
-
(1996)
Toxicologist Toxicol. Appl. Pharmacol. Suppl.
, vol.30
, pp. 232
-
-
Schoenfeld, H.A.1
Radbourne, R.2
Goldstein, B.D.3
Witz, G.4
-
62
-
-
2442753616
-
Effects of trans,trans-muconaldehyde, a hematotoxic benzene metabolite, on DNA-protein crosslink levels and on apoptosis in mouse bone marrow cells
-
abstr.
-
Schoenfeld, H. A., Mirochnitchenko, O., Goldstein, B. D., and Witz, G. 1997. Effects of trans,trans-muconaldehyde, a hematotoxic benzene metabolite, on DNA-protein crosslink levels and on apoptosis in mouse bone marrow cells. Toxicologist Toxicol. Appl. Pharmacol. Suppl. 36:163-164 (abstr.).
-
(1997)
Toxicologist Toxicol. Appl. Pharmacol. Suppl.
, vol.36
, pp. 163-164
-
-
Schoenfeld, H.A.1
Mirochnitchenko, O.2
Goldstein, B.D.3
Witz, G.4
-
63
-
-
2442734978
-
DNA-Protein crosslink (DNAPC) induction in bone marrow cells of mice administered benzene and reductive stabilization of DNAPC induced in vitro by trans,trans-muconaldehyde
-
abstr.
-
Schoenfeld, H. A., Goldstein, B. D., and Witz, G. 1998. DNA-Protein crosslink (DNAPC) induction in bone marrow cells of mice administered benzene and reductive stabilization of DNAPC induced in vitro by trans,trans-muconaldehyde. Toxicol. Sci. 42(1-S):79 (abstr.).
-
(1998)
Toxicol. Sci.
, vol.42
, Issue.1 S
, pp. 79
-
-
Schoenfeld, H.A.1
Goldstein, B.D.2
Witz, G.3
-
64
-
-
0021273314
-
Alkaline elution of rat testicular DNA: Detection of DNA cross-links after in vivo treatment with chemical mutagens
-
Skare, J. A., and Schrotel, K. R. 1984. Alkaline elution of rat testicular DNA: detection of DNA cross-links after in vivo treatment with chemical mutagens. Mutat. Res. 130:295-303.
-
(1984)
Mutat. Res.
, vol.130
, pp. 295-303
-
-
Skare, J.A.1
Schrotel, K.R.2
-
65
-
-
0030473213
-
The mechanism of benzene-induced leukemia: A hypothesis and speculations on the causes of leukemia
-
Smith, M. T. 1996. The mechanism of benzene-induced leukemia: A hypothesis and speculations on the causes of leukemia. Environ. Health Perspect. 104(Suppl. 6):1219-1225.
-
(1996)
Environ. Health Perspect.
, vol.104
, Issue.6 SUPPL.
, pp. 1219-1225
-
-
Smith, M.T.1
-
66
-
-
0024433243
-
Studies on the mechanism of benzene toxicity
-
Snyder, R., Dimitriadis, E., Guy, R., Hu, P, Cooper, K., Bauer, H., Witz, G., and Goldstein, B. D. 1989. Studies on the mechanism of benzene toxicity. Environ. Health Perspect. 82:31-35.
-
(1989)
Environ. Health Perspect.
, vol.82
, pp. 31-35
-
-
Snyder, R.1
Dimitriadis, E.2
Guy, R.3
Hu, P.4
Cooper, K.5
Bauer, H.6
Witz, G.7
Goldstein, B.D.8
-
67
-
-
0024401169
-
DNA damage and cyotoxicity of nitracrine in cultured HeLa cells
-
Szmigiero, L., and Studzian, K. 1989. DNA damage and cyotoxicity of nitracrine in cultured HeLa cells. Biochim. Biophys. Acta. 1008:339-345.
-
(1989)
Biochim. Biophys. Acta.
, vol.1008
, pp. 339-345
-
-
Szmigiero, L.1
Studzian, K.2
-
68
-
-
0028997977
-
Effects of topoisomerase I-targeted drugs on radiation response of L5178Y sublines differentially radiation and drug sensitive
-
Szumiel, I., Buraczewska, I., Gradzka, I., and Gasinska, A. 1995. Effects of topoisomerase I-targeted drugs on radiation response of L5178Y sublines differentially radiation and drug sensitive. Int. J. Radiat. Biol. 67:441-448.
-
(1995)
Int. J. Radiat. Biol.
, vol.67
, pp. 441-448
-
-
Szumiel, I.1
Buraczewska, I.2
Gradzka, I.3
Gasinska, A.4
-
69
-
-
0029594538
-
Increased DNA-protein crosslinks in lymphocytes of residents living in chromium-contaminated areas
-
Taioli, E., Zhitkovich, A., Kinney, P., Udasin, I., Toniolo, P., and Costa, M. 1995. Increased DNA-protein crosslinks in lymphocytes of residents living in chromium-contaminated areas. Biol. Trace Element Res. 50:175-180.
-
(1995)
Biol. Trace Element Res.
, vol.50
, pp. 175-180
-
-
Taioli, E.1
Zhitkovich, A.2
Kinney, P.3
Udasin, I.4
Toniolo, P.5
Costa, M.6
-
70
-
-
0018188521
-
DNA cross-linking by in vivo treatment with 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea of sensitive and resistant human colon carcinoma xenografts in nude mice
-
Thomas, C. B., Osieka, R., and Kohn, K. W. 1978. DNA cross-linking by in vivo treatment with 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea of sensitive and resistant human colon carcinoma xenografts in nude mice. Cancer Res. 38:2448-2454.
-
(1978)
Cancer Res.
, vol.38
, pp. 2448-2454
-
-
Thomas, C.B.1
Osieka, R.2
Kohn, K.W.3
-
71
-
-
0029124259
-
Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin
-
Toyokuni, S., Mori, T., Hiai, H., and Dizdaroglu, M. 1995. Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin. Int. J. Cancer. 62:309-313.
-
(1995)
Int. J. Cancer.
, vol.62
, pp. 309-313
-
-
Toyokuni, S.1
Mori, T.2
Hiai, H.3
Dizdaroglu, M.4
-
72
-
-
0021018936
-
Chromium(VI)-induced DNA lesions and chromium distribution in rat kidney, liver and lung
-
Tsapakos, M. J., Hampton, T. H., and Wetterhahn, K. E. 1983. Chromium(VI)-induced DNA lesions and chromium distribution in rat kidney, liver and lung. Cancer Res. 43:5662-5667.
-
(1983)
Cancer Res.
, vol.43
, pp. 5662-5667
-
-
Tsapakos, M.J.1
Hampton, T.H.2
Wetterhahn, K.E.3
-
73
-
-
0028179362
-
Interaction of trans,trans-muconaldehyde with bovine serum albumin
-
Udupi, V., Goldstein, B. D., and Witz, G. 1994. Interaction of trans,trans-muconaldehyde with bovine serum albumin. Arch. Biochem. Biophys. 310:385-391.
-
(1994)
Arch. Biochem. Biophys.
, vol.310
, pp. 385-391
-
-
Udupi, V.1
Goldstein, B.D.2
Witz, G.3
-
74
-
-
0027509495
-
Evaluation of DNA damage by alkaline elution technique after inhalation exposure of rats and mice to 1,3-butadiene
-
Vangala, R. R., Laib, R. J., and Bolt, H. M. 1993. Evaluation of DNA damage by alkaline elution technique after inhalation exposure of rats and mice to 1,3-butadiene. Arch. Toxicol. 67:34-38.
-
(1993)
Arch. Toxicol.
, vol.67
, pp. 34-38
-
-
Vangala, R.R.1
Laib, R.J.2
Bolt, H.M.3
-
75
-
-
0027410448
-
Cytotoxicity, DNA cross-linking, and DNA single-strand breaks induced by cyclophosphamide in a rat leukemia in vivo
-
Wang, J. Y., Prorok, G., and Vaughan, W. P. 1993. Cytotoxicity, DNA cross-linking, and DNA single-strand breaks induced by cyclophosphamide in a rat leukemia in vivo. Cancer Chemother. Pharmacol. 31:381-386.
-
(1993)
Cancer Chemother. Pharmacol.
, vol.31
, pp. 381-386
-
-
Wang, J.Y.1
Prorok, G.2
Vaughan, W.P.3
-
76
-
-
0024456697
-
Biological interactions of α,β-unsaturated aldehydes
-
Witz, G. 1989. Biological interactions of α,β-unsaturated aldehydes. Free Radical Biol. Med. 7:333-349.
-
(1989)
Free Radical Biol. Med.
, vol.7
, pp. 333-349
-
-
Witz, G.1
-
77
-
-
0021933310
-
Short term toxicity of trans,trans-muconaldehyde
-
Witz, G., Rao, G. S., and Goldstein, B. D. 1985. Short term toxicity of trans,trans-muconaldehyde. Toxicol. Appl. Pharmacol. 80:511-516.
-
(1985)
Toxicol. Appl. Pharmacol.
, vol.80
, pp. 511-516
-
-
Witz, G.1
Rao, G.S.2
Goldstein, B.D.3
-
78
-
-
0025278233
-
Genetic toxicity of the benzene metabolite trans,trans-muconaldehyde in mammalian and bacterial cells
-
Witz, G., Gad, S. C., Tice, R. R., Oshiro, Y., Piper, C. E., and Goldstein, B. D. 1990. Genetic toxicity of the benzene metabolite trans,trans-muconaldehyde in mammalian and bacterial cells. Mutat. Res. 240:295-306.
-
(1990)
Mutat. Res.
, vol.240
, pp. 295-306
-
-
Witz, G.1
Gad, S.C.2
Tice, R.R.3
Oshiro, Y.4
Piper, C.E.5
Goldstein, B.D.6
-
79
-
-
0030464771
-
Reactive ring-opened aldehyde metabolites in benzene hematotoxicity
-
Witz, G., Zhang, Z., and Goldstein, B. D. 1996. Reactive ring-opened aldehyde metabolites in benzene hematotoxicity. Environ. Health Perspect. 104(Suppl. 6):1195-1225.
-
(1996)
Environ. Health Perspect.
, vol.104
, Issue.6 SUPPL.
, pp. 1195-1225
-
-
Witz, G.1
Zhang, Z.2
Goldstein, B.D.3
-
80
-
-
0028288462
-
Topo-isomerase II mediated DNA lesions induced by acridine-4-carboxamide and 2-(4-pyridyl)quinoline-8-carboxamide
-
Woynarowski, J. M., McCarthy, K., Reynolds, B., Beerman, T. A., and Denny, W. A. 1994. Topo-isomerase II mediated DNA lesions induced by acridine-4-carboxamide and 2-(4-pyridyl)quinoline-8-carboxamide. Anti-Cancer Drug Design. 9:9-24.
-
(1994)
Anti-Cancer Drug Design.
, vol.9
, pp. 9-24
-
-
Woynarowski, J.M.1
McCarthy, K.2
Reynolds, B.3
Beerman, T.A.4
Denny, W.A.5
-
81
-
-
0029057913
-
Hematological studies of 6-hydroxy-trans,trans-2,4-hexadienal in CD-1 mice
-
Zhang, Z., Schafer, F., Schoenfeld, H., Cooper, K., Snyder, R., Goldstein, B. D., and Witz, G. 1995. Hematological studies of 6-hydroxy-trans,trans-2,4-hexadienal in CD-1 mice. Toxicol. Appl. Pharmacol. 132:213-219.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.132
, pp. 213-219
-
-
Zhang, Z.1
Schafer, F.2
Schoenfeld, H.3
Cooper, K.4
Snyder, R.5
Goldstein, B.D.6
Witz, G.7
-
83
-
-
0026802253
-
A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo
-
Zhitkovich, A., and Costa, M. 1992. A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. Carcinogenesis 13:1485-1489.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1485-1489
-
-
Zhitkovich, A.1
Costa, M.2
|