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1
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0013581923
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Brantford Chemicals Inc., Station Main P.O. Box 1979, Brantford, Ontario, N3T 5W5 CANADA
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(a) Brantford Chemicals Inc., Station Main P.O. Box 1979, Brantford, Ontario, N3T 5W5 CANADA
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2
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0013611160
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Department of Chemistry, Queen's University, Kingston, Ontario, K7L 3N6 CANADA; email: baderadm@chem.queensu.ca
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(b) Department of Chemistry, Queen's University, Kingston, Ontario, K7L 3N6 CANADA; email: baderadm@chem.queensu.ca
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3
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0000632045
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Cava, M.P.1
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(b) Rigby, J. H. In Comprehensive Organic Synthesis Trost. M. B.; Fleming, I., Eds.; Pergamon: 1991, New York, Vol. 5, p 638.
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Oppolzer, W. In Comprehensive Organic Chemistry: Trost. M. B.; Fleming, I.; Paquette, L. A., Eds.; Pergamon: 1991, New York, Vol. 5, p 315. Chalton, J. L.; Alauddin, M. M. Tetrahedron 1987, 2873.
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(d) Pindur, U. In Adv. Nitrogen Heterocycles; Moody, C. J., Ed.; Jai: London, 1995, Vol. 1, p 121.
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33845183730
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For a study in the naphthalene series, M.Sc. Thesis, University of Waterloo
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Mills, R. J.; Taylor, N. J.; Snieckus, V. J. Org. Chem. 1989, 54, 4372. For a study in the naphthalene series, see Puumala, K. M.Sc. Thesis, University of Waterloo, 1997.
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Snieckus, V.5
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23
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0013614131
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M.Sc. Thesis, University of Waterloo
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For example, reaction of 12 with methyl acrylate under CsF or TBAF conditions described for 13 gave, in addition to the expected cycloadducts 14, indole-N Michael addition products. Kinsman, A. C. M.Sc. Thesis, University of Waterloo, 1997.
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Kinsman, A.C.1
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0013628635
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13C COSY experiments on these mixtures suggested that the C-8 ester is the major isomer.
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13C COSY experiments on these mixtures suggested that the C-8 ester is the major isomer.
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0022539063
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(a) Asselin, A. A; Humber, L. G.; Voith, K.; Metcalf, G. J. Med. Chem. 1986, 29, 648.
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0028344738
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(b) Lin, C.-H.; Ennis, M. D.; Hoffman, R. L.; Phillips, G.; Haadsma-Svensson, S. R.; Ghazal, N. B.; Chidester, C. G. J. Heterocyclic Chem. 1994, 31, 129. Biological activity: Wikstrom, H.; Andersson, B.; Svensson, A.; Humber, L.G.; Asselin, A. A.; Svensson, K.; Ekman, A.; Carlsson, A.; Nilsson, I.; Chidester, C. J. Med. Chem. 1989, 32, 2273.
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0024449694
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(b) Lin, C.-H.; Ennis, M. D.; Hoffman, R. L.; Phillips, G.; Haadsma-Svensson, S. R.; Ghazal, N. B.; Chidester, C. G. J. Heterocyclicchem. 1994, 31, 129. Biological activity: Wikstrom, H.; Andersson, B.; Svensson, A.; Humber, L.G.; Asselin, A. A.; Svensson, K.; Ekman, A.; Carlsson, A.; Nilsson, I.; Chidester, C. J. Med. Chem. 1989, 32, 2273.
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Ekman, A.7
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Nilsson, I.9
Chidester, C.10
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0013581430
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X-ray structure of 17. (Formula presented)
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X-ray structure of 17. (Formula presented)
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0013578484
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Control experiments indicated that this product distribution was the result of isomerization of dimethyl maleate under the reaction conditions coupled with the relatively rapid cycloaddition rate of dimethyl fumarate.
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Control experiments indicated that this product distribution was the result of isomerization of dimethyl maleate under the reaction conditions coupled with the relatively rapid cycloaddition rate of dimethyl fumarate.
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1HNMR). Inability to separate the isomers or to obtain crystalline materials has precluded structural elucidation. See reference 12. For analogous dimers in the benzene series, see Ito, Y.; Nakatsuka, M.; Saegusa, T. J. Am. Chem. Soc. 1982, 104, 7609.
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Ito, Y.1
Nakatsuka, M.2
Saegusa, T.3
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13C NMR, IR, LRMS and either elemental analysis or HRMS
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13C NMR, IR, LRMS and either elemental analysis or HRMS.
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