Imaging protein kinase Cα activation in cells

Science

Volumn 283, Issue 5410, 1999, Pages 2085-2089

  Ng, Tony ^a,c   Squire, Anthony ^a,c   Hansra, Gurdip ^a   Bornancin, Frederic ^a,c   Prevostel, Corinne ^a   Hanby, Andrew ^b   Harris, William ^b   Barnes, Diana ^b   Schmidt, Sandra ^a   Mellor, Harry ^a   Bastiaens, Philippe I H ^a   Parker, Peter J ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

^c SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; DYNAMICS; ENERGY TRANSFER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; BREAST NEOPLASMS; CATALYSIS; COS CELLS; CYTOPLASM; ENDOPLASMIC RETICULUM; ENERGY TRANSFER; ENZYME ACTIVATION; FLUORESCENCE; FLUORESCENT DYES; GOLGI APPARATUS; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNE SERA; ISOENZYMES; LUMINESCENT PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; PHOSPHOTHREONINE; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION;

ANIMALIA;

EID: 0033605542     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.283.5410.2085     Document Type: Article

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27. We thank G. Warren and D. Shima (ICRF) for their valuable comments and for antibodies to p62, galactosyl transferase, p115, and giantin. We also thank M. Zerial (European Molecular Biology Laboratory) for a polyclonal antiserum to Rab7. We are grateful to D. Pappin and H. Hansen for protein sequencing.