Congenital insulin resistance associated with a conformational alteration in a conserved β-sheet in the insulin receptor L1 domain

Journal of Biological Chemistry

Volumn 274, Issue 26, 1999, Pages 18487-18491

  Rouard, Mathias ^a,b,c   Bass, Joseph ^b   Grigorescu, Florin ^a   Garrett, Thomas P J ^d   Ward, Colin W ^d   Lipkind, Gregory ^b   Jaffiole, Claude ^a   Steiner, Donald F ^b   Bell, Graeme I ^b  

^a Institut Universitaire de Recherche   (France)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d MC 1028 ^*

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS;

BIOTINYLATION; CELL LINE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, INSULIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0033603548     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.26.18487     Document Type: Article

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