Valine 571 functions as a regional organizer in programming the glucocorticoid receptor for differential binding of glucocorticoids and mineralocorticoids

Journal of Biological Chemistry

Volumn 274, Issue 26, 1999, Pages 18515-18523

  Lind, Ulrika ^a   Greenidge, Paulette ^b   Gustafsson, Jan Åke ^a,c   Wright, Anthony P H ^c,d   Carlstedt Duke, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Karo Bio   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d SÖDERTÖRN UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONFORMATIONAL TRANSITION; HORMONE RECEPTOR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR AFFINITY; RECEPTOR BINDING;

ALDOSTERONE; AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; COS CELLS; GLUCOCORTICOIDS; LIGANDS; MINERALOCORTICOIDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRIAMCINOLONE ACETONIDE; VALINE;

ANIMALIA;

EID: 0033603421     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.26.18515     Document Type: Article

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