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Volumn 144, Issue 2, 1999, Pages 293-304

Characterization of a Chlamydomonas insertional mutant that disrupts flagellar central pair microtubule-associated structures

Author keywords

Chlamydomonas; Cilia; Flagella; Microtubule; Motility

Indexed keywords

ALLELE; ARTICLE; AXONEME; CHLAMYDOMONAS; CONTROLLED STUDY; FLAGELLUM; GENE INSERTION; MICROTUBULE; MUTANT; NONHUMAN; PHOTOPHOBIA; PHOTOTAXIS; PRIORITY JOURNAL;

EID: 0033601735     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.144.2.293     Document Type: Article
Times cited : (110)

References (45)
  • 1
    • 0019843582 scopus 로고
    • Central-pair microtubular complex of Chlamydomonas flagella: Polypeptide composition as revealed by analysis of mutants
    • Adams, G.M.W., B. Huang, G. Piperno, and D.J.L. Luck. 1981. Central-pair microtubular complex of Chlamydomonas flagella: polypeptide composition as revealed by analysis of mutants. J. Cell Biol. 91:69-76.
    • (1981) J. Cell Biol. , vol.91 , pp. 69-76
    • Adams, G.M.W.1    Huang, B.2    Piperno, G.3    Luck, D.J.L.4
  • 2
    • 0029125452 scopus 로고
    • Flagellar kinesins: New moves with an old beat
    • Bernstein, M. 1995. Flagellar kinesins: new moves with an old beat. Cell Motil. Cytoskelet. 32:125-128.
    • (1995) Cell Motil. Cytoskelet. , vol.32 , pp. 125-128
    • Bernstein, M.1
  • 3
    • 0028361291 scopus 로고
    • A new kinesin-like protein (Klp 1) localized to a single microtubule of the Chlamydomonas flagellum
    • Bernstein, M., P.L. Beech, S.G. Katz, and J.L. Rosenbaum. 1994. A new kinesin-like protein (Klp 1) localized to a single microtubule of the Chlamydomonas flagellum. J. Cell Biol. 125:1313-1326.
    • (1994) J. Cell Biol. , vol.125 , pp. 1313-1326
    • Bernstein, M.1    Beech, P.L.2    Katz, S.G.3    Rosenbaum, J.L.4
  • 4
    • 0019050328 scopus 로고
    • Calcium control of waveform in isolated flagellar axomenes of Chlamydomonas
    • Bessen, M., R.B. Fay, and G.B. Witman. 1980. Calcium control of waveform in isolated flagellar axomenes of Chlamydomonas. J. Cell Biol. 86:446-455.
    • (1980) J. Cell Biol. , vol.86 , pp. 446-455
    • Bessen, M.1    Fay, R.B.2    Witman, G.B.3
  • 5
    • 0023083510 scopus 로고
    • Bending patterns of Chlamydomonas flagella. IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function
    • Brokaw, C.J., and R. Kamiya. 1987. Bending patterns of Chlamydomonas flagella. IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function. Cell Motil. Cytoskelet. 8:68-75.
    • (1987) Cell Motil. Cytoskelet. , vol.8 , pp. 68-75
    • Brokaw, C.J.1    Kamiya, R.2
  • 6
    • 0021980634 scopus 로고
    • Bending patterns of Chlamydomonas flagella. III. A radial spoke head deficient mutant and a central pair deficient mutant
    • Brokaw, C.J., and D.J.L. Luck. 1985. Bending patterns of Chlamydomonas flagella. III. A radial spoke head deficient mutant and a central pair deficient mutant. Cell Motil. 5:195-208.
    • (1985) Cell Motil. , vol.5 , pp. 195-208
    • Brokaw, C.J.1    Luck, D.J.L.2
  • 8
    • 0015407263 scopus 로고
    • Further observations on the ultrastructure of cilia from Tetrahymena pyriformis
    • Chasey, D. 1972. Further observations on the ultrastructure of cilia from Tetrahymena pyriformis. Exp. Cell Res. 74:471-179.
    • (1972) Exp. Cell Res. , vol.74 , pp. 471-1179
    • Chasey, D.1
  • 9
    • 0021334462 scopus 로고
    • Genetic dissection of the central pair microtubules of the flagella of Chlamydomonas reinhardtii
    • Dutcher, S.K., B. Huang, and D.J.L. Luck. 1984. Genetic dissection of the central pair microtubules of the flagella of Chlamydomonas reinhardtii. J. Cell Biol. 98:229-236.
    • (1984) J. Cell Biol. , vol.98 , pp. 229-236
    • Dutcher, S.K.1    Huang, B.2    Luck, D.J.L.3
  • 10
    • 0028206103 scopus 로고
    • Kinesin-related proteins in eukaryotic flagella
    • Fox, L.A., K.E. Sawin, and W.S. Sale. 1994. Kinesin-related proteins in eukaryotic flagella. J. Cell Sci. 107:1545-1550.
    • (1994) J. Cell Sci. , vol.107 , pp. 1545-1550
    • Fox, L.A.1    Sawin, K.E.2    Sale, W.S.3
  • 11
    • 0030824396 scopus 로고    scopus 로고
    • Reactivation at low ATP distinguishes among classes of paralyzed flagella mutants
    • Frey, E., C.J. Brokaw, and C.K. Omoto. 1997. Reactivation at low ATP distinguishes among classes of paralyzed flagella mutants. Cell Motil. Cytoskelet. 38:91-99.
    • (1997) Cell Motil. Cytoskelet. , vol.38 , pp. 91-99
    • Frey, E.1    Brokaw, C.J.2    Omoto, C.K.3
  • 12
    • 0021889149 scopus 로고
    • Substructure of inner dynein arms, radial spokes, and the central pair/projection complex
    • Goodenough, U.W., and J.E. Heuser. 1985. Substructure of inner dynein arms, radial spokes, and the central pair/projection complex. J. Cell Biol. 100: 2008-2018.
    • (1985) J. Cell Biol. , vol.100 , pp. 2008-2018
    • Goodenough, U.W.1    Heuser, J.E.2
  • 13
    • 0031022258 scopus 로고    scopus 로고
    • Regulation of flagellar dynein by phosphorylation of a 138-kD inner arm dynein intermediate chain
    • Habermacher, G., and W.S. Sale. 1997. Regulation of flagellar dynein by phosphorylation of a 138-kD inner arm dynein intermediate chain. J. Cell Biol. 136:167-176.
    • (1997) J. Cell Biol. , vol.136 , pp. 167-176
    • Habermacher, G.1    Sale, W.S.2
  • 15
    • 0020825406 scopus 로고
    • Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella
    • Hoops, H.J., and G.B. Witman. 1983. Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella. J. Cell Biol. 97:902-908.
    • (1983) J. Cell Biol. , vol.97 , pp. 902-908
    • Hoops, H.J.1    Witman, G.B.2
  • 16
    • 0029199749 scopus 로고
    • Cilia and Flagella. W. Dentler and G. Witman, editors. Academic Press Inc., San Diego.
    • Horst, C.J., and G.B. Witman. 1995. Reactivation of Chlamydomonas cell models. In Cilia and Flagella. W. Dentler and G. Witman, editors. Academic Press Inc., San Diego. 207-210.
    • (1995) Reactivation of Chlamydomonas Cell Models , pp. 207-210
    • Horst, C.J.1    Witman, G.B.2
  • 17
    • 0028007426 scopus 로고
    • Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase
    • Howard, D.R., G. Habermacher, D.B. Glass, E.F. Smith, and W.S. Sale. 1994. Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase. J. Cell Biol. 127:1683-1692.
    • (1994) J. Cell Biol. , vol.127 , pp. 1683-1692
    • Howard, D.R.1    Habermacher, G.2    Glass, D.B.3    Smith, E.F.4    Sale, W.S.5
  • 18
    • 0020082250 scopus 로고
    • Suppressor mutations in Chlamydomonas reveal a regulatory mechanism for flagellar function
    • Huang, B., Z. Ramanis, and D.J.L. Luck. 1982. Suppressor mutations in Chlamydomonas reveal a regulatory mechanism for flagellar function. Cell 28:115-124.
    • (1982) Cell , vol.28 , pp. 115-124
    • Huang, B.1    Ramanis, Z.2    Luck, D.J.L.3
  • 19
    • 0028179468 scopus 로고
    • Localization of a kinesin-related protein to the central pair apparatus of the Chlamydomonas reinhardtii flagellum
    • Johnson, K.A., M.A. Haas, and J.L. Rosenbaum. 1994. Localization of a kinesin-related protein to the central pair apparatus of the Chlamydomonas reinhardtii flagellum. J. Cell Sci. 107:1551-1556.
    • (1994) J. Cell Sci. , vol.107 , pp. 1551-1556
    • Johnson, K.A.1    Haas, M.A.2    Rosenbaum, J.L.3
  • 20
    • 0031012517 scopus 로고    scopus 로고
    • Phosphoregulation of an inner dynein arm complex in Chlamydomonas reinhardtii is altered in phototactic mutant strains
    • King, S.J., and S.K. Dutcher. 1997. Phosphoregulation of an inner dynein arm complex in Chlamydomonas reinhardtii is altered in phototactic mutant strains. J. Cell Biol. 136:177-191.
    • (1997) J. Cell Biol. , vol.136 , pp. 177-191
    • King, S.J.1    Dutcher, S.K.2
  • 21
    • 0019441007 scopus 로고
    • Arrangement of tubulin subunits and microtubule-associated proteins in the central pair microtubule apparatus of squid (Loligo pealei) sperm flagella
    • Linck, R.W., G.E. Olson, and G.L. Langevin. 1981. Arrangement of tubulin subunits and microtubule-associated proteins in the central pair microtubule apparatus of squid (Loligo pealei) sperm flagella. J. Cell Biol. 89:309-322.
    • (1981) J. Cell Biol. , vol.89 , pp. 309-322
    • Linck, R.W.1    Olson, G.E.2    Langevin, G.L.3
  • 23
    • 0025770089 scopus 로고
    • Identification of oda6 as a Chlamydomonas dynein mutant by rescue with the wild-type gene
    • Mitchell, D.R., and Y. Kang. 1991. Identification of oda6 as a Chlamydomonas dynein mutant by rescue with the wild-type gene. J. Cell Biol. 113:835-842.
    • (1991) J. Cell Biol. , vol.113 , pp. 835-842
    • Mitchell, D.R.1    Kang, Y.2
  • 24
    • 0030922765 scopus 로고    scopus 로고
    • Heterotrimeric kinesin-II is required for the assembly of motile 9 + 2 ciliary axonemes on sea urchin embryos
    • Morris, R.L., and J.M. Scholey. 1997. Heterotrimeric kinesin-II is required for the assembly of motile 9 + 2 ciliary axonemes on sea urchin embryos. J. Cell Biol. 138:1009-1022.
    • (1997) J. Cell Biol. , vol.138 , pp. 1009-1022
    • Morris, R.L.1    Scholey, J.M.2
  • 25
    • 0030956345 scopus 로고    scopus 로고
    • The Chlamydomonas Dhc1 gene encodes a dynein heavy chain subunit required for assembly of the I1 inner arm complex
    • Myster, S.H., J.A. Knott, E. O'Toole, and M.E. Porter. 1997. The Chlamydomonas Dhc1 gene encodes a dynein heavy chain subunit required for assembly of the I1 inner arm complex. Mol. Biol. Cell. 8:607-620.
    • (1997) Mol. Biol. Cell. , vol.8 , pp. 607-620
    • Myster, S.H.1    Knott, J.A.2    O'Toole, E.3    Porter, M.E.4
  • 26
    • 0018332854 scopus 로고
    • Axonemal adenosine triphosphatases from flagella of Chlamydomonas reinhardtii
    • Piperno, G., and D.J.L. Luck. 1979. Axonemal adenosine triphosphatases from flagella of Chlamydomonas reinhardtii. J. Biol. Chem. 254:3084-3090.
    • (1979) J. Biol. Chem. , vol.254 , pp. 3084-3090
    • Piperno, G.1    Luck, D.J.L.2
  • 27
    • 0026673055 scopus 로고
    • The inner dynein arms 12 interact with a "dynein regulatory complex" in Chlamydomonas flagella
    • Piperno, G., K. Mead, and W. Shestak. 1992. The inner dynein arms 12 interact with a "dynein regulatory complex" in Chlamydomonas flagella. J. Cell Biol. 118:1455-1463.
    • (1992) J. Cell Biol. , vol.118 , pp. 1455-1463
    • Piperno, G.1    Mead, K.2    Shestak, W.3
  • 28
    • 0026674076 scopus 로고
    • Extragenic suppressors of paralyzed flagellar mutations in Chlamydomonas reinhardtii identify loci that alter the inner dynein arms
    • Porter, M.E., J. Power, and S.K. Dutcher. 1992. Extragenic suppressors of paralyzed flagellar mutations in Chlamydomonas reinhardtii identify loci that alter the inner dynein arms. J. Cell Biol. 118:1163-1176.
    • (1992) J. Cell Biol. , vol.118 , pp. 1163-1176
    • Porter, M.E.1    Power, J.2    Dutcher, S.K.3
  • 29
    • 0028040415 scopus 로고
    • Mutations in the SUP-PF-1 locus of Chlamydomonas reinhardtii identify a regulatory domain in the beta dynein heavy chain
    • Porter, M.E., J.A. Knott, L.C. Gardner, D.R. Mitchell, and S.K. Dutcher. 1994. Mutations in the SUP-PF-1 locus of Chlamydomonas reinhardtii identify a regulatory domain in the beta dynein heavy chain. J. Cell Biol. 126:1495-1507.
    • (1994) J. Cell Biol. , vol.126 , pp. 1495-1507
    • Porter, M.E.1    Knott, J.A.2    Gardner, L.C.3    Mitchell, D.R.4    Dutcher, S.K.5
  • 30
    • 0030463112 scopus 로고    scopus 로고
    • The sup-pf-2 mutations of Chlamydomonas alter the activity of the outer dynein arms by modification of the gamma-dynein heavy chain
    • Rupp, G., E. O'Toole, L.C. Gardner, B.F. Mitchell, and M.E. Porter. 1996. The sup-pf-2 mutations of Chlamydomonas alter the activity of the outer dynein arms by modification of the gamma-dynein heavy chain. J. Cell Biol. 135: 1853-1865.
    • (1996) J. Cell Biol. , vol.135 , pp. 1853-1865
    • Rupp, G.1    O'Toole, E.2    Gardner, L.C.3    Mitchell, B.F.4    Porter, M.E.5
  • 31
    • 0344390094 scopus 로고
    • Direction of active sliding of microtubules in Tetrahymena cilia
    • Sale, W.S., and P. Satir. 1977. Direction of active sliding of microtubules in Tetrahymena cilia. Prof. Natl. Acad. Sci. USA. 74:2045-2049.
    • (1977) Prof. Natl. Acad. Sci. USA , vol.74 , pp. 2045-2049
    • Sale, W.S.1    Satir, P.2
  • 32
    • 0026517912 scopus 로고
    • Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies
    • Sawin, K.E., T.J. Mitchison, and L.G. Wordeman. 1992. Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies. J. Cell Sci. 101:303-313.
    • (1992) J. Cell Sci. , vol.101 , pp. 303-313
    • Sawin, K.E.1    Mitchison, T.J.2    Wordeman, L.G.3
  • 33
    • 0030034346 scopus 로고    scopus 로고
    • PF16 encodes a protein with armadillo repeats and localizes to a single microtubule of the central apparatus in Chlamydomonas flagella
    • Smith, E.F., and P.A. Lefebvre. 1996. PF16 encodes a protein with armadillo repeats and localizes to a single microtubule of the central apparatus in Chlamydomonas flagella. J. Cell Biol. 132:359-370.
    • (1996) J. Cell Biol. , vol.132 , pp. 359-370
    • Smith, E.F.1    Lefebvre, P.A.2
  • 34
    • 0030867993 scopus 로고    scopus 로고
    • The role of central apparatus components in flagellar motility and microtubule assembly
    • Smith, E.F., and P.A. Lefebvre. 1997. The role of central apparatus components in flagellar motility and microtubule assembly. Cell Motil. Cytoskelet. 38:1-8.
    • (1997) Cell Motil. Cytoskelet. , vol.38 , pp. 1-8
    • Smith, E.F.1    Lefebvre, P.A.2
  • 35
    • 0026768745 scopus 로고
    • Regulation of dynein-driven microtubule sliding by the radial spokes in flagella
    • Smith, E.F., and W.S. Sale. 1992. Regulation of dynein-driven microtubule sliding by the radial spokes in flagella. Science. 257:1557-1559.
    • (1992) Science , vol.257 , pp. 1557-1559
    • Smith, E.F.1    Sale, W.S.2
  • 36
    • 0026029731 scopus 로고
    • Computer modeling of Tetrahymena axonemes at macromolecular resolution
    • Sugrue, P., J. Avolio, P. Satir, and M.E.J. Holwill. 1991. Computer modeling of Tetrahymena axonemes at macromolecular resolution. J. Cell Sci. 98:5-16.
    • (1991) J. Cell Sci. , vol.98 , pp. 5-16
    • Sugrue, P.1    Avolio, J.2    Satir, P.3    Holwill, M.E.J.4
  • 37
    • 0027451262 scopus 로고
    • Cloning of flagellar genes in Chlamydomonas reinhardtii by DNA insertional mutagenesis
    • Tam, L.-W., and P.A. Lefebvre. 1993. Cloning of flagellar genes in Chlamydomonas reinhardtii by DNA insertional mutagenesis. Genetics. 135:375-384.
    • (1993) Genetics , vol.135 , pp. 375-384
    • Tam, L.-W.1    Lefebvre, P.A.2
  • 39
    • 0030612180 scopus 로고    scopus 로고
    • 2+-dependent waveform conversion in the flagellar axoneme of Chlamydomonas mutants lacking the central-pair radial spoke system
    • 2+-dependent waveform conversion in the flagellar axoneme of Chlamydomonas mutants lacking the central-pair radial spoke system. Cell Motil. Cytoskelet. 38:22-28.
    • (1997) Cell Motil. Cytoskelet. , vol.38 , pp. 22-28
    • Wakabayashi, K.1    Yagi, T.2    Kamiya, R.3
  • 40
    • 0017287435 scopus 로고
    • Ciliary inter-microtubule bridges
    • Warner, F.D. 1976. Ciliary inter-microtubule bridges. J. Cell Sci. 20:101-114.
    • (1976) J. Cell Sci. , vol.20 , pp. 101-114
    • Warner, F.D.1
  • 41
    • 0016209362 scopus 로고
    • The structural basis of ciliary bend formation. Radial spoke positional changes accompanying microtubule sliding
    • Warner, F.D., and P. Satir. 1974. The structural basis of ciliary bend formation. Radial spoke positional changes accompanying microtubule sliding. J. Cell Biol. 63:35-63.
    • (1974) J. Cell Biol. , vol.63 , pp. 35-63
    • Warner, F.D.1    Satir, P.2
  • 42
    • 0017396809 scopus 로고
    • Structural conformation of the ciliary ATPase dynein
    • Warner, F.D., D.R. Mitchell, and C.R. Perkins. 1977. Structural conformation of the ciliary ATPase dynein. J. Mol. Biol. 114:367-384.
    • (1977) J. Mol. Biol. , vol.114 , pp. 367-384
    • Warner, F.D.1    Mitchell, D.R.2    Perkins, C.R.3
  • 43
    • 84971812228 scopus 로고
    • Genetic control of flagellar structure in Chlamydomonas reinhardtii
    • Warr, J.R., A. McVittae, J. Randall, and J.M. Hopkins. 1966. Genetic control of flagellar structure in Chlamydomonas reinhardtii. Genet. Res. 7:335-351.
    • (1966) Genet. Res. , vol.7 , pp. 335-351
    • Warr, J.R.1    McVittae, A.2    Randall, J.3    Hopkins, J.M.4
  • 44
    • 0017944399 scopus 로고
    • Chlamydomonas flagellar mutants lacking radial spokes and central tubules
    • Witman, G.B., J. Plummer, and G. Sander. 1978. Chlamydomonas flagellar mutants lacking radial spokes and central tubules. J. Cell Biol. 76:729-747.
    • (1978) J. Cell Biol. , vol.76 , pp. 729-747
    • Witman, G.B.1    Plummer, J.2    Sander, G.3
  • 45
    • 0019882018 scopus 로고
    • Silver staining of proteins in polyacrylamide gels
    • Wray, W., T. Boulikas, V.P. Wray, and R. Hancock. 1981. Silver staining of proteins in polyacrylamide gels. Anal. Biochem. 118:197-203.
    • (1981) Anal. Biochem. , vol.118 , pp. 197-203
    • Wray, W.1    Boulikas, T.2    Wray, V.P.3    Hancock, R.4


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