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Volumn 64, Issue 26, 1999, Pages 9337-9347

Stereospecific synthesis of functionalized ether phospholipids

Author keywords

[No Author keywords available]

Indexed keywords

ETHER PHOSPHOLIPID;

EID: 0033601204     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo990739v     Document Type: Article
Times cited : (20)

References (43)
  • 6
    • 0002800621 scopus 로고
    • Immunopathology
    • Bad Schachen; Niescher, P. A., Ed.; Schwabe: Basel
    • (a) Munder, P. G.; Weltzien, H. O.; Modolell, M. Immunopathology, VIIth Int. Symposium, Bad Schachen; Niescher, P. A., Ed.; Schwabe: Basel, 1976, pp 411-424.
    • (1976) VIIth Int. Symposium , pp. 411-424
    • Munder, P.G.1    Weltzien, H.O.2    Modolell, M.3
  • 25
    • 0343528463 scopus 로고    scopus 로고
    • note
    • (b) The availability of this compound in high enantiomeric excess (>99%) makes it preferable to other glycidol derivatives for the stereospecific synthesis of phospholipids.
  • 28
    • 0343528462 scopus 로고    scopus 로고
    • note
    • In some cases, the addition of activated molecular sieves seemed to be helpful in removing traces of moisture from the reaction mixture, thereby increasing the reactivity of the anionic nucleophile (see the Experimental Section).
  • 31
    • 0343092565 scopus 로고    scopus 로고
    • note
    • The N-triphenylmethyl derivatives of serine methyl ester and threonine methyl ester were prepared by the method described in ref 22a; they were obtained in 91 and 89% yields, respectively.
  • 34
    • 0343528460 scopus 로고    scopus 로고
    • note
    • We found that, contrary to the previous report, the pure oxazoline 11 is quite stable at room temperature (for at least several weeks). (b) Preparation of iodide 13 turned out to be necessary, because direct displacement of the tosylate with sodium iodide gave poor yields of compound 14.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.