The binding sites of inhibitory monoclonal antibodies on acetylcholinesterase. Identification of a novel regulatory site at the putative 'back door'

Journal of Biological Chemistry

Volumn 274, Issue 39, 1999, Pages 27740-27746

  Simon, Stéphanie ^a   Goff, Anne Le ^a   Frobert, Yveline ^b   Grassi, Jacques ^b   Massoulié, Jean ^a  

^a ECOLE NORMALE SUPÉRIEURE   (France)

^b Institut National de la Recherche Agronomique   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; MONOCLONAL ANTIBODY;

ANTIGEN BINDING; ARTICLE; BINDING SITE; COMPLEX FORMATION; ELECTROPHORUS; ENZYME ACTIVE SITE; ENZYME BINDING; IMMUNOGLOBULIN STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS;

ACETYLCHOLINESTERASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; CHOLINESTERASE INHIBITORS; ELAPID VENOMS; ELECTROPHORUS; EPITOPES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PEPTIDE FRAGMENTS; RATS; RECOMBINANT FUSION PROTEINS; XENOPUS LAEVIS;

EID: 0033600795     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.39.27740     Document Type: Article

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