Engineered recombinant factor VII Q217 variants with altered inhibitor specificities

Biochemistry

Volumn 38, Issue 34, 1999, Pages 10940-10948

  Chang, Yu Jia ^d   Hamaguchi, Nobuko ^a   Chang, Shu Chuan ^d   Ruf, Wolfram ^b   Shen, Ming Ching ^d   Lin, Shu Wha ^c  

^a BRANDEIS UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN III; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 9; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TISSUE FACTOR PATHWAY INHIBITOR;

AMINO ACID COMPOSITION; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; DRUG SYNTHESIS; ENZYME ACTIVITY; GENETIC ENGINEERING; GENETIC TRANSFECTION; HEMOPHILIA A; MICHAELIS CONSTANT; MOLECULAR CLONING; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTHROMBIN TIME; REACTION TIME; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; ANTICOAGULANTS; ANTITHROMBIN III; BLOOD COAGULATION TESTS; CATALYSIS; CELL LINE; CHROMOGENIC COMPOUNDS; FACTOR VII; FACTOR X; FACTOR XA; GENE EXPRESSION REGULATION; GLUTAMINE; HUMANS; LIPOPROTEINS; MACROMOLECULAR SUBSTANCES; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; THROMBOPLASTIN; TRANSFECTION;

FELIS CATUS;

EID: 0033600591     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990055h     Document Type: Article

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