Fetal origins of adult disease—the hypothesis revisited

BMJ

Volumn 319, Issue 7204, 1999, Pages 245-

  Lucas, A ^a   Fewtrell, M S ^a   Cole, T J ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Institute of Child Health   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT DISEASE; BIRTH WEIGHT; FETUS DEVELOPMENT; HUMAN; PRIORITY JOURNAL; REVIEW; STATISTICAL ANALYSIS;

ADULT; BIRTH WEIGHT; CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 0033600420     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.319.7204.245     Document Type: Article

References (35)

1. Lucas A. Programming by early nutrition in man. In: Bock GR,Whelan J,eds. The childhood environment and adult disease. Chichester: Wiley, 1991: 38–55. (CIBA Foundation Symposium 156.)
2. Spalding DA. Instinct with original observation on young animals. Br J Animal Behav 1954; 2: 2–11. (Reprinted from Macmillan's Magazine 1873; 27: 282–93.)
3. Angelbeck J.H., Du Brul E.F., The effect of neonatal testosterone on specific male and female patterns of phosphorylated cytosolic proteins in the rat preoptic-hypothalamus, cortex and amygdala. Brain Res 1983; 264: 277–283.
4. McCance RA. Food, growth and time. Lancet 1962; ii: 271–272.
5. Hahn P. Effect of litter size on plasma cholesterol and insulin and some liver and adipose tissue enzymes in adult rodents. J Nutr 1984; 114: 1231–1234.
6. Mott G.E., Lewis D.S., McGill HC. Programming of cholesterol metabolism by breast or formula feeding. In: Bock GR,Whelan J,eds. The childhood environment and adult disease. Chichester: Wiley, 1991: 56–76. (CIBA Foundation Symposium 156.)
7. Dobbing J. Nutritional growth restriction and the nervous system. In: Davison AN,Thompson RHS,eds. The molecular bases of neuropathology. London: Edward Arnold, 1981: 221–233.
8. Smart J. Undernutrition, learning and memory: review of experimental studies. In: Taylor TG,Jenkins NK,eds. Proceedings of XII international congress of nutrition. London: John Libbey, 1986: 74–78.
9. Lucas A. Programming by early nutrition: an experimental approach. J Nutr 1998; 128(suppl 2): 401–46S.
10. Barker DJP ed. Fetal and infant origins of adult disease. London: BMJ Publishing, 1992.
11. Robinson S., Walton R.J., Clark P.M., Barker DJP, Hales C.N., Osmond C. The relation of fetal growth to plasma glucose in young men. Diabetologia 1992; 35: 444–446.
12. Law C.M., Gordon G.S., Shiell A.W., Barker D.J.P., Hales CN. Thinness at birth and glucose tolerance in seven-year-old children. Diabet Med 1995; 12: 24–29.
13. Valdez R., Athens M.A., Thompson G.H., Bradshaw B.S., Stern MP. Birth weight and adult health outcomes in a biethnic population in the USA. Diabetologia 1994; 37: 624–631.
14. Barker DJP, Bull A.R., Osmond C., Simmonds SJ. Fetal and placental size and risk of hypertension in adult life. BMJ 1990; 301: 259–262.
15. Lithell H.O., McKeigue P.M., Berglund L., Mohsen R., Lithell U-B, Leon DA. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 1996; 312: 406–410.
16. Taylor S.J., Whincup P.H., Cook D.G., Papacosta O., Walker M. Size at birth and blood pressure: cross sectional study in 8-11 year old children. BMJ 1997; 314: 475–480.
17. Forrester T.E., Wilks R.J., Bennett F.I., Simeon D., Osmond C., Allen M., et al. Fetal growth and cardiovascular risk factors in Jamaican schoolchildren. BMJ 1996; 312: 56–60.
18. Fall CHD, Stein C.E., Kumaran K., Cox V., Osmond C., Barker DJP, et al. Size at birth, maternal weight and type 2 diabetes in South India. Diabetic Med 1998; 15: 220–227.
19. Law C.M., Barker DJP, Osmond C., Fall CHD, Simmonds SJ. Early growth and abdominal fatness in adult life. J Epidemiol Community Health 1992; 46: 184–186.
20. Fall CHD, Pandit A.N., Law C.M., Yajnik C.S., Clark P.M., Breier B., et al. Size at birth and plasma insulin-like growth factor-1 concentrations. Arch Dis Child 1995; 73: 287–293.
21. Whincup P.H., Cook D.G., Adshead F., Taylor SJC, Walker M., Papacosta O., et al. Childhood size is more strongly related than size at birth to glucose and insulin levels in 10-11-year-old children. Diabetologia 1997; 40: 319–326.
22. Leon DA. Fetal growth and adult disease. Eur J Clin Nutr 1998; 52(suppl 1): S72–S82.
23. Law C.M., De Swiet M., Osmond C., Fayers P.M., Barker DJP, Cruddas A.M., et al. Initiation of hypertension in utero and its amplification throughout life. BMJ 1993; 306: 24–27.
24. Phipps K., Barker DJP, Hales C.N., Fall CHD, Osmond C., Clark PMS. Fetal growth and impaired glucose tolerance in men and women. Diabetologia 1993; 36: 225–228.
25. Yajnik C.S., Fall CHD, Vaidya U., Pandit A.N., Bavdekar A., Bhat D.S., et al. Fetal growth and glucose and insulin metabolism in four-year-old Indian children. Diabet Med 1995; 12: 330–336.
26. Fall CHD, Osmond C., Barker DJP, Clark PMS, Hales C.N., Stirling Y., et al. Fetal and infant growth and cardiovascular risk factors in women. BMJ 1995; 310: 428–432.
27. Vijayakumar M., Fall CHD, Osmond C., Barker DJP. Birth weight, weight at one year and left ventricular mass in adult life. Br Heart J 1995; 73: 363–367.
28. Langley-Evans S.C., Phillips G.J., Jackson AA. In utero exposure to maternal low protein diets induces hypertension in weaning rats, independently of maternal blood pressure changes. Clin Nutr 1994; 13: 319–324.
29. Lewis D.S., Bertrand H.A., McMahan C.A., McGill HC Jr, Carey KD, Masoro EJ. Preweaning food intake influences the adiposity of young adult baboons. J Clin Invest 1986; 78: 899–905.
30. Lewis D.S., Mott G.E., McMahan C.A., Masoro E.J., Carey K.D., McGill HC Jr. Deferred effects of preweaning diet on atherosclerosis in adolescent baboons. Arteriosclerosis 1988; 8: 274–280.
31. Fall CHD, Barker DJP, Osmond C., Winter P.D., Clark PMS, Hales CN. Relation of infant feeding to adult serum cholesterol concentration and death from ischaemic heart disease. BMJ 1992; 304: 801–805.
32. Phillips DIW, Barker DJP, Hales C.N., Hirst S., Osmond C. Thinness at birth and insulin resistance in adult life. Diabetologia 1994; 37: 150–154.
33. Leon D.A., Koupilova I., Lithell H.O., Berglund L., Mohsen R., Vagero D., et al. Failure to realise growth potential in utero and adult obesity in relation to blood pressure in 50 year old Swedish men. BMJ 1996; 312: 401–406.
34. Frankel S., Elwood P., Sweetnam P., Yarnell J., Davey Smith G. Birth weight, body-mass index in middle age, and incident coronary heart disease. Lancet 1996; 348: 1478–1480.
35. Eriksson J.G., Forsén T., Tuomilehto J., Winter P.D., Osmond C., Barker DJP. Catch-up growth in childhood and death from coronary heart disease: longitudinal study. BMJ 1999; 318: 427–431.