Sorting by diffusion: An asymmetric obstacle course for continuous molecular separation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 24, 1999, Pages 13762-13765

  Chou, Chia Fu ^a   Bakajin, Olgica ^a   Turner, Stephen W P ^b   Duke, Thomas A J ^c,d   Chan, Shirley S ^a   Cox, Edward C ^a   Craighead, Harold G ^b   Austin, Robert H ^a  

^a PRINCETON UNIVERSITY   (United States)

^b Cornell University   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Brownian motion; DNA fractionation; Microfabricated array

Indexed keywords

DNA FRAGMENT;

ANALYTIC METHOD; ARTICLE; DIFFUSION COEFFICIENT; FRACTIONATION; GENETIC ANALYSIS; MOLECULAR DYNAMICS; PRIORITY JOURNAL;

CHEMICAL FRACTIONATION; DIFFUSION; DNA;

EID: 0033598696     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.24.13762     Document Type: Article

References (15)

1. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual (2nd Ed.) (Cold Spring Harbor Lab. Press, Plainview, New York).
2. Volkmuth, W. D. & Austin, R. H. (1992) Nature (London) 358, 600-602.
3. Hoch, H. C., Jelinski, L. W. & Craighead, H. G., eds. (1996) Nanofabrication and Biosystems: Integrating Materials Science, Engineering, and Biology (Cambridge Univ. Press, Cambridge, U.K.).
4. Harrison, D. J. & van den Berg, A., eds. (1998) Micro Total Analysis Systems (Kluwer Academic, Boston).
5. Burns, M. A., Johnson, B. N., Brahmasandra, S. N., Handique, K., Webster, J. R., Krishnan, M., Sammarco, T. S., Man, P. M., Jones, D., Heldsinger, D., et al. (1998) Science 282, 484-487.
6. Duke, T. A. J. & Austin, R. H. (1998) Phys. Rev. Lett. 80, 1552-1555.
7. Ertas, D. (1998) Phys. Rev. Lett. 80, 1548-1551.
8. van Oudenaarden, A. & Boxer, S. G. (1999) Science 285, 1046-1048.
9. Turner, S. W., Perez, A. M., Lopez, A. & Craighead, H. G. (1998) J. Vac. Sci. Technol. B 38, 3835-3840.
10. Giddings, J. C. (1991) Unified Separation Science (Wiley, New York), pp. 101-106.
11. Bakajin, O. B., Duke, T. A. J., Chou, C. F., Chan, S. S., Austin, R. H. & Cox, E. C. (1998) Phys. Rev. Lett. 80, 2737-2740.
12. Zimm, B. H. (1956) J. Chem. Phys. 24, 269-278.
13. Rousselet, J., Salome, L., Ajdari, L. & Frost, J. (1994) Nature (London) 370, 446-448.
14. Faucheaux, L. P. & Libchaber, A. (1995) J. Chem. Soc. Faraday Trans. 91, 3163-3166.
15. Gorre-Talini, L., Jeanjean, S. & Silberzan, P. (1997) Phys. Rev. E 56, 2025-2034.