Stillbirths among offspring of male radiation workers at Sellafield nuclear reprocessing plant

Lancet

Volumn 354, Issue 9188, 1999, Pages 1407-1414

  Parker, Louise ^a   Pearce, Mark S ^a   Dickinson, Heather O ^a   Aitkin, Murray ^a   Craft, Alan W ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ENVIRONMENTAL EXPOSURE; FETUS; HUMAN; IONIZING RADIATION; MALE; NEURAL TUBE DEFECT; NEWBORN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RADIATION EXPOSURE; RISK; STILLBIRTH; UNITED KINGDOM;

EID: 0033598556     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)04138-0     Document Type: Article

References (39)

1. Scientific committee on the effects of atomic radiation UNSCEAR 1993 report of the general assembly, with scientific annexes: sources and effects of ionizing radiation. 1993;United Nations, New York.
2. Scientific committee on the effects of atomic radiation UNSCEAR 1994 report of the general assembly, with scientific annexes: sources and effects of ionizing radiation. 1994;United Nations, New York.
3. Lord B.I., Woolford L.B., Wang L.et al. Tumour induction by methyl-nitroso-urea following preconceptional paternal contamination with plutonium-239. Br J Cancer. 78:1998;301-311.
4. Cattenach B.M., Patrick G., Papworth D.et al. Investigation of lung tumour induction in BALB/cJ mice following paternal irradiation. Int J Radiat Biol. 67:1995;607-616.
5. Daher A., Varin M., Lamontagne Y., Oth D. Effect of pre-conceptional external or internal irradiation of N5 male mice and the risk of leukaemia in their offspring. Carcinogenesis. 19:1998;1553-1558.
6. Bobrow M. Committee on medical aspects of radiation in the environment (COMARE) second report: investigation of the possible increased incidence of leukaemia in young people near the Dounreay nuclear establishment, Caithness, Scotland. 1988;HM Stationery Office, London.
7. Gardner M.J., Snee M.P., Hall A.J., Powell C.A., Downes S., Terrell J.D. Results of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria. BMJ. 300:1990;423-429.
8. Parker L., Craft A.W., Smith J.et al. Geographical distribution of preconceptional radiation doses to fathers employed at the Sellafield nuclear installation, West Cumbria. BMJ. 307:1993;966-971.
9. Doll R., Evans H.J., Darby S.C. Paternal exposure not to blame. Nature. 367:1994;678-680.
10. Bridges B.A. Committee on medical aspects of radiation in the environment (COMARE) fourth report: the incidence of cancer and leukaemia in young people in the vicinity of the Sellafield site, West Cumbria - further studies and an update of the situation since the publication of the report of the Black Advisory Group in 1984. 1996;HMSO, London.
11. Draper G.J., Little M.P., Sorahan T.et al. Cancer in the offspring of radiation workers: a record linkage study. BMJ. 315:1997;1181-1188.
12. Wakeford R., Tawn E.J., McElvenny D.M.et al. The descriptive statistics and health implications of occupational radiation doses received by men at Sellafield nuclear installation before the conception of their children. J Radiol Protect. 14:1994;3-16.
13. Direct estimates of cancer mortality due to low doses of ionising radiation: an international study. Lancet. 344:1994;1039-1043.
14. Dickinson H., Parker L., Binks K., Wakeford R., Smith J. The sex ratio of children in relation to paternal preconceptional radiation dose: a study in Cumbria, northern England. J Epidemiol Commun Health. 50:1996;645-652.
15. Parker L., Smith J., Dickinson H.et al. The creation of a database of children of workers at a nuclear facility - an exercise in record linkage. Appl Occupat Environ Hygiene. 12:1997;40-46.
16. Dummer T.J.B., Dickinson H.O., Pearce M.S.et al. Stillbirth rates around the nuclear installation at Sellafield north west England: 1950-89. Int J Epidemiol. 27:1998;74-82.
17. Standard occupation classification, volumes 1, 2, and 3. 1990;HM Stationery Office, London.
18. Alberman E., Botting B., Blatchley N., Twidell A. A new hierarchical classification of causes of infant deaths in England and Wales. Arch Dis Child. 70:1994;403-409.
19. Mortality - series DH3. 1974-1993;HM Stationery Office, London.
20. Kite A.V., Britcher A.R. Uncertainties in recorded photon radiation doses at Sellafield. Radiat Protect Dos. 67:1996;23-32.
21. Individual monitoring for intakes of radionuclides by workers: design and interpretation. ICRP Pub no 54. 1988;Pergamon, Oxford.
22. MacFarlane A., Mugford M. Birth counts - statistics of pregnancy and childbirth. 1984;HM Stationery Office, London.
23. Birth statistics (series FM1 nos 1-19). 1974-90;HM Stationery Office, London.
24. Aitkin M. A general maximum likelihood analysis of overdispersion in generalized linear models. Stat Comp. 6:1996;251-262.
25. Aitkin M. A general maximum likelihood analysis of variance components in generalized linear models. Biometrics. 55:1999;218-234.
26. McCullagh P.M, Nelder J.A. Generalised linear models, 2nd edn. 1989;Wiley, New York.
27. Greenland S., Drescher K. Maximum likelihood estimation of the attributable fraction from logistic models. Biometrics. 49:1993;865-872.
28. Royston P., Altman D.G. Regression using fractional polynomials of continuous covariates: parsimonious parametric modelling. Appl Statist. 43:1994;429-467.
29. Sever L.E., Gilbert E.S., Hessol N.A., McIntyre J.M. A case-control study of congenital malformations and occupational exposure to low-level ionizing radiation. Am J Epidemiol. 127:1988;226-242.
30. Neel J.V., Schull W.J. The children of atomic bomb survivors: a genetic study. 1991;National Academy Press, Washington.
31. Russell W.L., Bangham J.W., Russell L.B. Differential response of mouse male germ-cell stages to radiation-induced specific-locus and dominant mutations. Genetics. 146:1998;1567-1578.
32. Denniston C., Chakraborty R., Sankaranarayanan K. Ionizing radiation and genetic risks - VIII: the concept of mutation component and its use in risk estimation for multifactorial diseases. Mutat Res. 405:1998;57-79.
33. Copp A.J. Prevention of neural tube defects: vitamins, enzymes and genes. Curr Opin Neurol. 11:1998;97-102.
34. Kirk K.M., Lyon M.F. Induction of congenital anomalies in the offspring of male mice treated with X-rays at pre-meiotic and post-meiotic stages. Mutat Res. 125:1984;75-85.
35. Brender J.D., Suarez L. Paternal occupation and anencephaly. Am J Epidemiol. 131:1990;517-521.
36. National Council on Radiation Protection and Measurements (NCRP Report no 126). Uncertainties in fatal cancer risk estimates used in radiation protection. Bethesda: NCRP Publications, 1997.
37. Breslow N.E., Day N.E. Statistical methods in cancer research, vol II - the design and analysis of cohort studies. 1987;IARC, Lyon.
38. Sever L.E., Hessol N., Gilbert E.S., McIntyre J.M. The prevalence at birth of congenital malformations in communities near the Hanford site. Am J Epidemiol. 127:1988;226-243.
39. Dummer T.J.B., Pearce M.S., Dickinson H.O., Charlton M.E., Salotti J., Parker L. Stillbirths in relation to the coastline of Cumbria: 1950-1989. Pediatr Perinat Epidemiol. 13:1999;131-137.