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Volumn 64, Issue 15, 1999, Pages 5551-5556

New strategies for the synthesis of fluorinated vinylogous amidines and β-enamino ketones

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; ENAMINOKETONE; IMIDOYL CHLORIDE; IMINE; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

EID: 0033597863     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo990392w     Document Type: Article
Times cited : (50)

References (52)
  • 1
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    • (1996) Tetrahedron , vol.52 , Issue.1 , pp. 319
    • Resnati, G.1    Soloshonok, V.A.2
  • 5
    • 0002485698 scopus 로고
    • Selective Fluorination in Organic and Bioorganic Chemistry
    • American Chemical Society: Whashington, DC
    • (b) Welch, J. T. Selective Fluorination in Organic and Bioorganic Chemistry, ACS Symposium Series 456; American Chemical Society: Whashington, DC, 1991.
    • (1991) ACS Symposium Series , vol.456
    • Welch, J.T.1
  • 11
    • 0032472096 scopus 로고    scopus 로고
    • See for example: (a) German, L.; Zemskov, S. New Fluorinating Agents in Organic Synthesis; Springer-Verlag: Berlin, Heidelberg, 1989. (b) Banks, R. E. J. Fluorine Chem. 1998, 87, 1-17.
    • (1998) J. Fluorine Chem. , vol.87 , pp. 1-17
    • Banks, R.E.1
  • 18
    • 17144471709 scopus 로고    scopus 로고
    • Trifluoromethylated Amino Alcohols: New Synthetic Approaches and Medicinal Targets
    • Ojima, I., McCarthy, J. R., Welch, J. T., Eds.; ACS Books, American Chemical Society: Washington, DC
    • (b) Bégué, J.-P.; Bonnet-Delpon, D. Trifluoromethylated Amino Alcohols: New Synthetic Approaches and Medicinal Targets. In Biomedical Frontiers of Fluorine Chemistry; Ojima, I., McCarthy, J. R., Welch, J. T., Eds.; ACS Books, American Chemical Society: Washington, DC, 1996; pp 59-72.
    • (1996) Biomedical Frontiers of Fluorine Chemistry , pp. 59-72
    • Bégué, J.-P.1    Bonnet-Delpon, D.2
  • 25
    • 0030960045 scopus 로고    scopus 로고
    • Corrigenda: Tetrahedron Lett. 1997, 38, 6477
    • (a) Fustero, S.; Navarro, A.; Asensio, A. Tetrahedron Lett. 1997, 38, 4891. Corrigenda: Tetrahedron Lett. 1997, 38, 6477.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 4891
    • Fustero, S.1    Navarro, A.2    Asensio, A.3
  • 30
    • 0029049296 scopus 로고
    • For related processes, see: (a) Bartoli, G.; Cimarelli, C.; Dalpozzo, R.; Palmieri, G. Tetrahedron 1995, 51, 8613. (b) Huang, W. S.; Yuan, C. I. J. Chem. Soc., Perkin Trans. 1 1995, 741. (c) See also ref 5b.
    • (1995) Tetrahedron , vol.51 , pp. 8613
    • Bartoli, G.1    Cimarelli, C.2    Dalpozzo, R.3    Palmieri, G.4
  • 31
    • 37049079689 scopus 로고
    • For related processes, see: (a) Bartoli, G.; Cimarelli, C.; Dalpozzo, R.; Palmieri, G. Tetrahedron 1995, 51, 8613. (b) Huang, W. S.; Yuan, C. I. J. Chem. Soc., Perkin Trans. 1 1995, 741. (c) See also ref 5b.
    • (1995) J. Chem. Soc., Perkin Trans. 1 , pp. 741
    • Huang, W.S.1    Yuan, C.I.2
  • 32
    • 0345306839 scopus 로고    scopus 로고
    • See also ref 5b
    • For related processes, see: (a) Bartoli, G.; Cimarelli, C.; Dalpozzo, R.; Palmieri, G. Tetrahedron 1995, 51, 8613. (b) Huang, W. S.; Yuan, C. I. J. Chem. Soc., Perkin Trans. 1 1995, 741. (c) See also ref 5b.
  • 34
    • 0345306837 scopus 로고    scopus 로고
    • note
    • In other examples due to overlapping peaks or broads signals, this assignment was more complex.
  • 48
    • 0344875721 scopus 로고    scopus 로고
    • note
    • In fact, Hojo methodology does not allow the synthesis of fluorinated cyclic β-enamino ketones such as 4a, 4d, and 4g (see Table 2, entries 1, 4-5, and 8).
  • 50
    • 0345306832 scopus 로고    scopus 로고
    • note
    • In some occasions, and only after prolonged heating, a complex mixture of products along with starting material was identified in the crude reaction mixture.
  • 51
    • 0344012679 scopus 로고    scopus 로고
    • note
    • The synthetic utility of related nonfluorinated derivatives has been successfully studied by Barluenga's group (see refs 9, 11, and 16).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.