DNA cleavage by the EcoRV restriction endonuclease: Roles of divalent metal ions in specificity and catalysis

Journal of Molecular Biology

Volumn 288, Issue 1, 1999, Pages 87-103

  Baldwin, Geoffrey S ^a   Sessions, Richard B ^a   Erskine, Symon G ^a   Halford, Stephen E ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

DNA protein interaction; Enzyme mechanism; Molecular dynamics; Phosphodiester hydrolysis; Restriction modification

Indexed keywords

COBALT; DNA; MAGNESIUM ION; MANGANESE; METAL ION; RESTRICTION ENDONUCLEASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA CLEAVAGE; DNA PROTEIN COMPLEX; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; PLASMID; PRIORITY JOURNAL; TURNOVER TIME;

EID: 0033597347     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.2672     Document Type: Article

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