Effects of TH-142177 on angiotensin II-induced proliferation, migration and intracellular signaling in vascular smooth muscle cells and on neointimal thickening after balloon injury

Life Sciences

Volumn 64, Issue 22, 1999, Pages 2061-2070

  Nozawa, Yoshihisa ^a,b   Matsuura, Naosuke ^a   Miyake, Hidekazu ^b   Yamada, Shizuo ^c   Kimura, Ryohei ^c  

^a Pharmacological Research Laboratory   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Angiotensin II; Mitogen activated protein kinase; Neointimal thickening; Proliferation; Protein kinase C; TH 142177; VSMC migration

Indexed keywords

1 (4 AMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDROIMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II [1 SARCOSINE 8 ISOLEUCINE]; GENISTEIN; IODINE 125; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; N,N BUTYL N [2' (1 H TETRAZOL 5 YL)BIPHENYL 4 YL]METHYL (N CARBOXYMETHYL BENZYLAMINO)ACETAMIDE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ENZYME ACTIVITY; MALE; NONHUMAN; RAT; RESTENOSIS; TRANSLUMINAL CORONARY ANGIOPLASTY; VASCULAR SMOOTH MUSCLE;

1-SARCOSINE-8-ISOLEUCINE ANGIOTENSIN II; ANGIOTENSIN II; ANIMALS; ARTERIOSCLEROSIS; BALLOON DILATATION; CAROTID ARTERY INJURIES; CAROTID ARTERY, COMMON; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; GLYCINE; HYPERPLASIA; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; SIGNAL TRANSDUCTION; TETRAZOLES;

ANIMALIA;

EID: 0033597181     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(99)00153-8     Document Type: Article

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