Synthesis of an 1-azaglucose analogue with ring-oxygen retained

Tetrahedron Letters

Volumn 40, Issue 17, 1999, Pages 3461-3464

  Bach, Peter ^a   Bols, Mikael ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

1 AZAGLUCOSE DERIVATIVE; GLYCOSIDASE INHIBITOR; ISOFAGOMINE; OXYGEN; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE ANALYSIS; DRUG EFFICACY; ENZYME INHIBITION; HYDROXYLATION; PROTON TRANSPORT; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0033597162     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00423-2     Document Type: Article

References (24)

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19. 4) and concentrated to a 2:1 mixture of 8 and 9 (1.7 g, 78%). By flash chromatography (EtOAc-pentane 1:2) 8 was isolated in 48% yield.
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22. 2O): δ 81.3 (C-5), 68.1 (C-3), 68.0 (C-4), 57.6 (C-6), 50.3 (C-2).
23. 2O): δ 71.7 (C-2), 64.7 (C-3), 64.5 (C-4), 57.2 (C-6), 57.1 (C-5).
24. 2 are 63.7 and 74.4 ppm, respectively (Aldrich NMR spectral collection).