Flexibility of interdomain contacts revealed by topological isomers of bivalent consolidated ligands to the dual Src homology domain SH(32) of Abelson

Biochemistry

Volumn 38, Issue 12, 1999, Pages 3491-3497

  Qinghong, Xu ^a,b   Zheng, Jie ^a   Xu, Rong ^a   Barany, George ^b   Cowburn, David ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b University of Minnesota   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CYTOARCHITECTURE; ISOMER; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PLIABILITY; PROTEIN CONFORMATION; SRC HOMOLOGY DOMAINS; STEREOISOMERISM;

EID: 0033596943     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982744j     Document Type: Article

References (27)

1. Netzer, W. J., and Hartl, U. F. (1997) Nature 388, 343-349.
2. Cohen, G. B., Ren, R., and Baltimore, D. (1995) Cell 80, 237-248.
3. Cowburn, D., and Kuriyan, J. (1996) in Signal Transduction (Heldin, C.-H., and Purton, M., Eds.) pp 127-142, Chapman & Hall, London.
4. Pawson, T. (1995) Nature 373, 573-580.
5. Eck, M. J., Atwell, S. K., Shoelson, S. E., and Harrison, S. C. (1994) Nature 368, 764-769.
6. Gosser, Y. Q., Zheng, J., Overduin, M., Mayer, B. J., and Cowburn, D. (1995) Structure 3, 1075-1086.
7. Nam, H. J., Haser, W. G., Roberts, T. M., and Frederick, C. A. (1996) Structure 4, 1105-1114.
8. Sicheri, F., Moarefi, I., and Kuriyan, J. (1997) Nature 385, 602-609.
9. Xu, W., Harrison, S. C., and Eck, M. J. (1997) Nature 385, 595-602.
10. Williams, J. C., Weijland, A., Gonfloni, S., Thompson, A., Courtneidge. S. A., Superti-Furga, G., and Wierenga, R. K. (1997) J. Mol. Biol. 274, 757-775.
11. Cowburn, D., Zheng, J., Xu, Q., and Barany, G. (1995) J. Biol. Chem. 270, 26738-26741.
12. Sicheri, F., and Kuriyan, J. (1997) Curr. Opin. Struct. Biol. 7, 777-785.
13. Maignan, S., Guilloteau, J. P., Fromage, N., Arnoux, B., Becquart, J., and Ducruix, A. (1995) Science 268, 291-293.
14. Rosen, M. K., Yamazaki, T., Gish, G. D., Kay, C. M., Pawson, T., and Kay, L. E. (1995) Nature 374, 477-479.
15. Mayer, B. J., Hirai, H., and Sakai, R. (1995) Curr. Biol. 5, 296-305.
16. Kuriyan, J., and Cowburn, D. (1997) Annu. Rev. Biophys. Biomol. Struct. 26, 259-288.
17. Alberico, F., Kneib-Cordonier, N., Biancalana, S., Gera, L., Masada, R. L., Hudson, D., and Barany, G. (1990) J. Org. Chem. 55, 3730-3743.
18. Ottinger, E. A., Shekels, L. L., Bernlohr, D. A., and Barany, G. (1993) Biochemistry 32, 4354-4361.
19. Xu, Q., Cowburn, D., Zheng, J., and Barany, G. (1996) Lett. Pept. Sci. 3, 31-36.
20. King, D. S., Fields, C. G., and Fields, G. B. (1990) Int. J. Pept. Protein Res. 36, 225.
21. Overduin, M., Rios, C., Mayer, B., Baltimore, D., and Cowburn, D. (1992) Cell 70, 697-704.
22. Musacchio, A., Saraste, M., and Wilmanns, M. (1994) Nat. Struct. Biol. 1, 546-551.
23. Evans, S. V. (1993) J. Mol. Graphics 11, 134-138.
24. Wiseman, T., Williston, S., Brandts, J. F., and Lin, L. N. (1989) Anal. Biochem. 179, 131-137.
25. Fushman, D., Xu, R., and Cowburn, D. (1998) (submitted for publication).
26. Feng, S., Chen, J. K., Yu, H., Simon, J. A., and Schreiber, S. L. (1994) Science 266, 1241-1247.
27. Shuker, S. B., Hajduk, P. J., Meadows, R. P., and Fesik, S. W. (1996) Science 274, 1531-1534.