Effect of interferon β on human myelin basic protein-specific T-cell lines: Comparison of IFNβ-1a and IFNβ-1b

Neurology

Volumn 52, Issue 5, 1999, Pages 1069-1071

  Weber, F ^a   Janovskaja, J ^b   Polak, T ^b   Poser, S ^b   Rieckmann, P ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA1A INTERFERON; INTERFERON BETA SERINE; MYELIN BASIC PROTEIN;

ANTIGEN SPECIFICITY; ANTIVIRAL ACTIVITY; ARTICLE; CELL PROLIFERATION; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; HUMAN; HUMAN CELL; IMMUNOMODULATION; LYMPHOCYTE CULTURE; MITOSIS INHIBITION; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0033596842     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.52.5.1069     Document Type: Article

References (10)

1. Suen WE, Bergman CM, Hjelmstrom P, Ruddle NH. A critical role for lymphotoxin in experimental allergic encephalomyelitis. J Exp Med 1997;186:1233-1240.
2. Rieckmann P, Albrecht M, Kitze B, et al. Tumor necrosis factor - a messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 1995;37:82-88.
3. Jacobs LD, Cookfair DL, Rudick RA, et al. Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann Neurol 1996;39:285-294.
4. The IFNb Multiple Sclerosis Study Group. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 1993;43:655-661.
5. Panitch HS. Influence of infection on exacerbations of multiple sclerosis. Ann Neurol 1994;36(suppl):S25-S28.
6. Weber F, Polak T, Günther A, et al. Synergistic immunomodulatory effects of interferon-β1b and the phosphodiesterase inhibitor pentoxifylline in patients with relapsing remitting multiple sclerosis. Ann Neurol 1998;44:27-34.
7. Rudick RA, Ransohoff RM, Peppler R, VanderBrug Medendorp S, Lehmann P, Alam J. Interferon beta induces interleukin-10 expression: relevance to multiple sclerosis. Ann Neurol 1996;40:618-627.
8. Pette M, Pette DF, Muraro PA, Farnon E, Martin R, McFarland HF. Interferon-beta interferes with the proliferation but not with the cytokine secretion of myelin basic protein-specific, T-helper type 1 lymphocytes. Neurology 1997; 49:385-392.
9. Porrini AM, Reder AT. IFN-gamma, IFN-beta, and PGE1 affect monokine secretion: relevance to monocyte activation in multiple sclerosis. Cell Immunol 1994;157:428-438.
10. de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;174:1209-1220.