Neurotransmitters, KCl and antioxidants rescue striatal neurons from apoptotic cell death in culture

Brain Research

Volumn 816, Issue 2, 1999, Pages 276-285

  Iacovitti, Lorraine ^a   Stull, Natalie D ^a   Mishizen, Amanda ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Growth factor; Neurotransmitter; Striatum; Tissue culture

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ALPHA TOCOPHEROL DERIVATIVE; ANTIOXIDANT; BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR BLOCKING AGENT; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; MELATONIN; MONOAMINE; NERVE GROWTH FACTOR; NEURITE PROMOTING FACTOR; NEUROTRANSMITTER; NEUROTROPHIN 3; POTASSIUM CHLORIDE; TROLOX C;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DENSITY; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; IMMUNOCYTOCHEMISTRY; MOUSE; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; TISSUE CULTURE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CORPUS STRIATUM; CULTURE MEDIA, SERUM-FREE; DOPAMINE AGONISTS; MEMBRANE POTENTIALS; MICE; NEURONS; NEUROTRANSMITTER AGENTS; POTASSIUM CHLORIDE;

EID: 0033596588     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00955-X     Document Type: Article

References (55)

1. Akaide A., Tamura Y., Terada K., Nakata N. Regulation by neuroprotective factors of NMDA receptor mediated nitric oxide synthesis in the brain and retina. Prog. Brain Res. 103:1994;391-403.
2. Black I.B. Environmental regulation of brain trophic interactions. Intl. J. Dev. Neurosci. 11:1993;403-410.
3. Buttke T.M., Sandstrom P.A. Oxidative stress as a mediator of apoptosis. Immunol. Today. 15:1994;7-10.
4. Choi D.W., Maulucci-Gedde M., Kriegstein A.R. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;357-368.
5. Collins F., Lile J.D. The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival. Brain Res. 502:1989;99-108.
6. Creveling C.R., Lundstrom J., McNeal E.T., Tice L., Daly J.W. Dihydroxytryptamines: effects on noradrenergic function in mouse heart in vivo. Mol. Pharmacol. 11:1975;211-222.
7. Deshmukh M., Johnson E.M. Jr. Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Mol. Pharmacol. 51:1997;897-906.
8. DiPorzio U., Smith S.V., Novotny E.A., Morelli F., Baker J.L. Two functionally different glutamate receptors of the kainate subtype in embryonic rat mesencephalic cells. Exp. Neurol. 120:1993;202-213.
9. Du X., Iacovitti L. Synergy between growth factors and neurotransmitters required for catecholamine differentiation in brain neurons. J. Neurosci. 15:1995;5420-5427.
10. Du X., Stull N.D., Iacovitti L. Novel expression of the tyrosine hydroxylase gene requires both acidic fibroblast growth factor and an activator. J. Neurosci. 14:1994;7688-7694.
11. Du X., Stull N.D., Iacovitti L. Brain-derived neurotrophic factor works coordinately with partner molecules to initiate tyrosine hydroxylase expression in striatal neurons. Brain Res. 680:1995;229-233.
12. G. Fishell, D. van der Kooy, Pattern formation in the striatum: neurons with early projections to the substantia nigra survive the cell death period.
13. Franklin J.L., Johnson E.M. Jr. Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium. Trends Neurosci. 15:1992;501-508.
14. Graham D.G., Tiffany S.M., Bell W.R. Jr., Gutknecht W.F. Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro. Mol. Pharmacol. 14:1978;644-653.
15. Graveland G.A., Williams R.S., DiFiglia M. Evidence of degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease. Science. 227:1985;770-773.
16. Greenlund L.J.S., Deckwerth T.L., Johnson E.M. Jr. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron. 14:1995;303-315.
17. Han S.-K., Mytilineou C., Cohen G. L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J. Neurochem. 66:1996;501-510.
18. Iacovitti L., Evinger M.J., Joh T.H., Reis D.J. A muscle-derived factor induces expression of a catecholamine phenotype in cultured rat cerebral cortex. J. Neurosci. 9:1989;3529-3537.
19. Iwahashi H., Ishii T., Sugata R., Kido R. The effects of caffeic acid and its related catechols on hydroxyl radical formation by 3-hydroxyanthranilic acid, ferric chloride, and hydrogen peroxide. Arch. Biochem. Biophys. 276:1990;242-247.
20. Johnson E.M. Jr., Deckwerth T.L. Molecular mechanisms of developmental neuronal death. Annu. Rev. Neurosci. 16:1993;31-46.
21. Kawabata T., Schepkin V., Harmaki N., Phadke R.S., Packer L. Iron coordination by catechol derivative antioxidants. Biochem. Pharmacol. 51:1996;1569-1577.
22. Kerr J.F.R., Wyllie H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
23. 2+ determine nerve growth factor dependence of sympathetic ganglion cells. Proc. Natl. Acad. Sci. USA. 86:1989;6421-6425.
24. 2+ influx. J. Neurobiol. 26:1995;205-212.
25. Lauder J.M. Neurotransmitters as morphogens. Prog. Brain Res. 73:1988;365-387.
26. Lipton S.A., Kater S.B. Neurotransmitter regulation of neuronal outgrowth, plasticity and survival. TINS. 12:1989;265-270.
27. Liu J., Mori A. Monoamine metabolism provides an antioxidant defense in the brain against oxidant- and free radical-induced damage. Arch. Biochem. Biophys. 302:1993;118-127.
28. Mattson M.P. Neurotransmitters in the regulation of neuronal architecture. Brain Res. Rev. 13:1988;179-212.
29. Mattson M.P., Dou P., Kater S.B. Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons. J. Neurosci. 8:1988;1704-1711.
30. Meier E., Hertz L., Schousboe A. Neurotransmitters as developmental signals. Neurochem. Int. 19:1991;1-15.
31. Mena M.A., Pardo B., Casarejos M.J., Fahn S., de Yebenes J.G. Neurotoxicity of levodopa on catecholamine-rich human neuroblastoma cells. Mov. Disord. 5:1992;62-73.
32. Meyer-Franke A., Kaplan M.R., Pfrieger F.W., Barres B.A. Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron. 15:1995;805-819.
33. Miller T.M., Johnson E.M. Jr. Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells. J. Neurosci. 16:1996;7487-7495.
34. Miura T., Muraoka S., Ogiso T. Lipid peroxidation inhibited by monoamines. Res. Commun. Mol. Pathol. Pharmacol. 93:1996;57-67.
35. Mytilineou C., Han S.-K., Cohen G. Toxic and protective effects of L-DOPA on mesenchephalic cell cultures. J. Neurochem. 61:1993;1470-1478.
36. + concentrations on the growth and development of ciliary ganglion neurons in cell culture. Dev. Biol. 87:1981;301-307.
37. Noh J.S., Gwag B.J. Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures. Exp. Neurol. 146:1997;604-608.
38. Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:1991;453-501.
39. Pardo B., Mena M.A., Casarejos M.J., Paino C.L., De Yebenes J.G. Toxic effects of L-DOPA on mesencephalic cell cultures: protection with antioxidants. Brain Res. 682:1995;133-143.
40. Pettmann B., Henderson C.E. Neuronal cell death. Neuron. 20:1998;633-647.
41. D. Purves, Body and brain: a trophic theory of neural connections, Harvard Univ. Press, Cambridge, MA.
42. Purves D., Snider W.D., Voyvodic J.T. Trophic regulation of nerve cell morphology and innervation in the autonomic nervous system. Nature (London). 336:1988;123-128.
43. Rosenberg P.A. Catecholamine toxicity in cerebral cortex in dissociated cell culture. J. Neurosci. 8:1988;2887-2894.
44. Schambra U.B., Duncan G.E., Breese G.E., Fornaretto M.G., Caron M.G., Fremeau R.T. Jr. Ontogeny of D1A and D2 dopamine receptor subtypes in rat brain using in situ hybridization and receptor binding. Neuroscience. 62:1994;65-85.
45. Scott B.S., Fisher K.C. Potassium concentration and number of neurons in cultures of dissociated ganglia. Exp. Neurol. 27:1970;16-22.
46. Shi W.-X., Zheng P., Liang X.-F., Bunney B.S. Characterization of dopamine-induced depolarization of prefrontal cortical neurons. Synapse. 26:1997;415-422.
47. Spencer J.P., Jenner A., Butler J., Aruoma O.I., Dexter D.T., Jenner P., Halliwell B. Evaluation of the pro-oxidant and antioxidant actions of L-DOPA and dopamine in vitro: implications for Parkinson's disease. Free Radic. Res. 24:1996;95-105.
48. Stull N.D., Iacovitti L. Neurotransmitters protect brain neurons from cell death in serum-deprived low density cultures. Soc. Neurosci. Abstr. 22:1996.
49. Stull N.D., Iacovitti L. Neurotransmitters but not trophic factors rescue striatal neurons from cell death in low density serum-deprived cultures. Soc. Neurosci. Abstr. 23:1997.
50. D. van der Kooy, Early postnatal lesions of the substantia nigra produce massive shrinkage of the rat striatum, disruption of patch neuron distribution, but no loss of patch neurons, Devel. Brain Res., 1996, pp. 242-245.
51. Ventimiglia R., Mather P.E., Jones B.E., Lindsay R.M. The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur. J. Neurosci. 7:1995;213-222.
52. + concentrations support the survival of chick embryo sympathetic neurons. Exp. Cell Res. 144:1983;377-384.
53. Widmer H.R., Hefti F. Neurotrophin-4/5 promotes survival and differentiation of rat striatal neurons developing in culture. Eur. J. Neurosci. 6:1994;1669-1679.
54. Yu S.P., Yeh C.-H., Sensi S.L., Gwag B.J., Canzoniero L.M.T., Farhangrazi Z.S., Ying H.S., Tian M., Dugan L.L., Choi D.W. Mediation of neuronal apoptosis by enhancement of outward potassium current. Science. 278:1997;114-117.
55. Zhou Q.-Y., Palmiter R.D. Dopamine-deficient mice are hypoactive, adipsic and aphagic. Cell. 83:1995;1197-1209.