Thermal melting studies with PNA and PNA-DNA chimera

Tetrahedron Letters

Volumn 40, Issue 43, 1999, Pages 7671-7674

  Kuimelis, Robert G ^a   Van der Laan, Alexander C ^b   Vinayak, Ravi ^a  

^a APPLIED BIOSYSTEMS   (United States)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; COMPLEMENTARY RNA; HETERODUPLEX; PEPTIDE NUCLEIC ACID;

ARTICLE; CHIMERA; DRUG DESIGN; MELTING POINT; STRUCTURE ANALYSIS;

EID: 0033595878     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01586-5     Document Type: Article

References (8)

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2. Nielsen, P. E.; Egholm, M., Eds. Peptide Nucleic Acids: Protocols and Applications; Horizon Scientific Press: Wymondham, England, 1999.
3. Uhlmann, E.; Will, D. W.; Breipohl, G.; Langner, D.; Ryte, A. Angew. Chem., Int. Ed. Engl. 1996, 35, 2632-2635; Uhlmann, E. Bio. Chem. 1998, 379, 1045-1052.
4. Uhlmann, E.; Will, D. W.; Breipohl, G.; Langner, D.; Ryte, A. Angew. Chem., Int. Ed. Engl. 1996, 35, 2632-2635; Uhlmann, E. Bio. Chem. 1998, 379, 1045-1052.
5. Finn, P. J.; Gibson, N. J.; Fallon, R.; Hamilton, A.; Brown, T. Nucleic Acids Res. 1996, 24, 3357-3364.
6. 6 t*: tetrabutylammonium salt of N-(2-hydroxyethyl)-N-(thymin-l-yl-acetyl)glycine.
7. van der Laan, A. C.; Brill, R.; Kuimelis, R. G.; Kuyl-Yeheskiely, E.; van Boom, J. H.; Andrus, A.; Vinayak, R. Tetrahedron Lett. 1997, 2249-2252.
8. Giesen, U.; Kleider, W.; Berding, C.; Geiger, A.; Orum, H.; Nielsen, P. E. Nucleic Acids Res. 1998, 26, 5004-5006.