Diastereoselective synthesis of β-amino-α-hydroxy phosphonates via oxazaborolidine catalyzed reduction of β-phthalimido-α-keto phosphonates

Tetrahedron Letters

Volumn 40, Issue 43, 1999, Pages 7705-7708

  Barco, Achille ^a   Benetti, Simonetta ^a   Bergamini, Paola ^a   De Risi, Carmela ^b   Marchetti, Paolo ^b   Pollini, Gian P ^b   Zanirato, Vinicio ^c  

^a Dipartimento di Chimica   (Italy)

^b Dipto di Scienze Farmaceutiche   (Italy)

^c UNIVERSITY OF SIENA   (Italy)

Author keywords

Amino acid derivatives; Amino acids; Arbuzov reaction; Phosphonic acid derivatives; Phosphonic acids

Indexed keywords

ALPHA AMINO ACID; AMINO ACID; AMINO ACID DERIVATIVE; BORANE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL MODIFICATION; CHEMICAL REACTION; REDUCTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 0033595868     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01573-7     Document Type: Article

References (13)

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8. 4) and concentrated. The residue was dissolved in EtOAc and the HCl salt of the aminoalcohol precipitated as previously described. The filtrate was concentrated and the residue purified by flash chromatography.
9. Corey, E. J.; Helal, C. J. Angew. Chem., Int. Ed. Engl. 1998, 37, 1986-2012 and references cited therein.
10. 31P NMR: 21.71.
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13. 31P NMR: δ 25.