5-aryl-1,2,3,4-tetrahydrochromeno[3,4-f]quinolin-3-ones as a novel class of nonsteroidal progesterone receptor agonists: Effect of A-ring modification

Journal of Medicinal Chemistry

Volumn 42, Issue 8, 1999, Pages 1466-1472

  Zhi, Lin ^a   Tegley, Christopher M ^a   Marschke, Keith B ^a   Mais, Dale E ^a   Jones, Todd K ^a,b  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b Ontogen Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 ARYL 1,2,3,4 TETRAHYDROCHROMENO[3,4]QUINOLIN 3 ONE DERIVATIVE; ANTINEOPLASTIC AGENT; GESTAGEN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BREAST CANCER; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING, COMPETITIVE; BREAST NEOPLASMS; CELL LINE; CERCOPITHECUS AETHIOPS; HUMANS; LIGANDS; QUINOLONES; RECEPTORS, PROGESTERONE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0033594377     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980723h     Document Type: Article

References (14)

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