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85069422469
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For the synthesis of 1 and 2, see Supporting Information
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For the synthesis of 1 and 2, see Supporting Information.
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27
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85069424660
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note
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Determined by a TOA autotitrater AUT-301 and analyzed by the nonlinear least-squares method.
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28
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0030335064
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Tamura, Z.1
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Ito, K.3
Maeda, M.4
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29
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85069422038
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See Supporting Information for Figure S-1
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See Supporting Information for Figure S-1.
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30
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85069423314
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note
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The MacroModel/MM2 (version 4.5) force field was used. See Supporting Information for the most stable conformations of the complex a (n = 9) and that of n = 5.
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32
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85069421751
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note
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The apparent association constants (K′) were determined in the following manner. K= [complex]/[1] [diamine 4] [N-ethylpiperidine] where [N-ethylpiperidine] ≫ [complex] and [1]. Thus, [N-ethylpiperidine] can be adequately approximated to constant ∴ K′ = K[N-ethylpiperidine] = [complex]/[1] [diamine 4].
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