Synthesis and voltage-clamp studies of methyl 1,4-dihydro-2,6-dimethyl- 5-nitro-4-(benzofurazanyl)pyridine-3-carboxylate racemates and enantiomers and of their benzofuroxanyl analogues

Journal of Medicinal Chemistry

Volumn 42, Issue 8, 1999, Pages 1422-1427

  Visentin, Sonja ^a   Amiel, Pascale ^a   Fruttero, Roberta ^a   Boschi, Donatella ^a   Roussel, Christian ^b   Giusta, Laura ^a   Carbone, Emilio ^a   Gasco, Alberto ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 (BENZOFURAZANYL)PYRIDINE 3 CARBOXYLIC ACID; 1,4 DIHYDROPYRIDINE DERIVATIVE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; ION CHANNEL; METHYL 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 (BENZOFURAZAN 4 YL)PYRIDINE 3 CARBOXYLIC ACID; METHYL 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 (BENZOFURAZAN 5 YL)PYRIDINE 3 CARBOXYLIC ACID; METHYL 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 (BENZOFUROXAN 4(7) YL)PYRIDINE 3 CARBOXYLIC ACID; METHYL 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 (BENZOFUROXAN 5(6) YL)PYRIDINE 3 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSULINOMA; NONHUMAN; RAT; TEMPERATURE DEPENDENCE; VOLTAGE CLAMP;

ANIMALS; BENZOXAZOLES; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; ION CHANNEL GATING; PATCH-CLAMP TECHNIQUES; PYRIDINES; RATS; STEREOISOMERISM; TUMOR CELLS, CULTURED;

EID: 0033594337     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980623b     Document Type: Article

References (24)

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