Synthesis of 5,8-dimethoxy-3-hydroxy-4-quinolone, a reported inhibitor of HIV RT, and evidence the original proposed structure was incorrect

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 4, 1999, Pages 543-546

  Zembower, David E ^a   Aytes, Shelley A ^a  

^a MediChem Research Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 QUINOLONE DERIVATIVE; 5,6 DIMETHOXY 3 HYDROXY 4 QUINOLONE; ANILINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; PROTON NUCLEAR MAGNETIC RESONANCE;

HIV-1 REVERSE TRANSCRIPTASE; HYDROXYQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; QUINOLONES; REVERSE TRANSCRIPTASE INHIBITORS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0033593871     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00046-3     Document Type: Article

References (10)

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10. (b) Reitsema, R. H. Chem. Rev. 1948, 43, 43-68.