The RNA-editing enzyme ADAR1 is localized to the nascent ribonucleoprotein matrix on Xenopus lampbrush chromosomes but specifically associates with an atypical loop

Journal of Cell Biology

Volumn 144, Issue 4, 1999, Pages 603-615

  Eckmann, Christian R ^a   Jantsch, Michael F ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Chromosomal localization; Epitope tagging; RNA editing; RNA splicing; Xenopus oocytes

Indexed keywords

ADENOSINE DEAMINASE; DOUBLE STRANDED RNA; RIBONUCLEOPROTEIN;

ANIMAL CELL; ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME; ENZYME SUBSTRATE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RNA EDITING; XENOPUS LAEVIS;

ADENOSINE DEAMINASE; ANIMALS; ANTIBODIES; BASE SEQUENCE; BINDING SITES; CHROMOSOMES; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RABBITS; RIBONUCLEOPROTEINS; RNA EDITING; RNA SPLICING; VARIATION (GENETICS); XENOPUS LAEVIS;

AMPHIBIA; ANIMALIA; REPTILIA; XENOPUS LAEVIS;

EID: 0033593786     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.144.4.603     Document Type: Article

References (49)

1. Bass, B.L. 1997. RNA-editing and hypermulation by adenosine deamination. Trends Biochem Sci. 22:157-162.
2. Bass, B.L., and H. Weintraub. 1987. A developmentally regulated activity that unwinds RNA duplexes. Cell. 48:607-613.
3. Bass, B.L., and H. Weintraub. 1988. An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell. 55:1089-1098.
4. Bass, B.L., K. Nishikura, W. Keller, P.H. Seeburg, R.B. Emeson, M.A. O'Connell, C.E. Samuel, and A. Herbert. 1997. A standardized nomenclature for adenosine deaminases that act on RNA. RNA. 3:947-949.
5. Baurén, G., and L. Wieslander. 1994. Splicing of Balbiani ring 1 gene premRNA occurs simultaneously wuh transcription. Cell. 76:183-192.
6. Beyer, A.L., and Y.N. Osheim. 1998. Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. Genes Dev. 2:754-765.
7. Brooks, R., C.R. Eckmann, and M.F. Jantsch. 1998. The double-stranded RNA-binding domains of Xenopus laevis ADAR1 exhibit different RNA-binding behaviors. FEBS Lett. 434:121-126.
8. Burns, C.M., H. Chu, S.M. Rueter, L.K. Hutchinson, H. Canton, E. Sanders-Bush, and R.B. Emeson. 1997. Regulation ot serotonin-2C receptor G-protein coupling by RNA editing. Nature. 387:303-308.
9. Callan, H.G. 1986. Lampbrush chromosomes. M. Solioz, editor. Springer Verlag, Berlin.
10. Cattaneo, R., A. Schmid, D. Eschle, K. Baczko, V. ter Meulen, and M.A. Billeter. 1988. Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell. 55:255-265.
11. Dabiri, G.A., F. Lai, R.A. Drakas, and K. Nishikura. 1996. Editing of the GluR-B ion channel RNA in vitro by recombinant double-stranded RNA adenosine deaminase. EMBO (Eur. Mol. Biol. Organ.) J. 15:34-45.
12. Eckmann, C.R., and M.F. Jantsch. 1997. Xlrbpa, a double-stranded RNA-binding protein associated with ribosomes and hnRNAs. J. Cell Biol. 138:239-253.
13. Evan, G., G. Lewis, G. Ramsay, and M. Bishop. 1985. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:3610-3636.
14. Fu, X.D., and T. Maniatis. 1990. Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature. 343:437-441.
15. Gerber, A., H. Grosjean, T. Melcher, and W. Keller. 1998. Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2. EMBO (Eur. Mol. Biol. Organ.) J. 17:4780-4789.
16. Herb, A., M. Higuchi, R. Sprengel, and P.H. Seeburg. 1996. Q/R site editing in kainate receptor GluR5 an GluR6 pre-mRNAs requires distant intronic sequences. Proc. Natl. Acad. Sci. USA. 93:1875-1880.
17. Herbert, A., J. Alfken, Y.-G. Kim, I.S. Mian, K. Nishikura, and A. Rich. 1997. A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase. Proc. Natl. Acad. Sci. USA. 94:8421-8426.
18. Higuchi, M., F.N. Single, M. Köhler, B. Sommer, R. Sprengel, and P.H. Seeburg. 1993. RNA editing of AMPA receptor subunit GluR-B: a base-paired exon-intron structure determines position and efficiency. Cell. 75:1361-1370.
19. Hough, R.F., and B.L. Bass. 1994. Purification of the Xenopus laevis double-stranded RNA adenosine deaminase. J. Biol. Chem. 269:9933-9939.
20. Hough, R.F., and B.L. Bass. 1997. Analysis of Xenopus dsRNA adenosine deaminase cDNAs reveals similarities to DNA methyltransferases. RNA. 3:356-370.
21. Hulsebos, T.J., J.H. Hackstein, and W. Hennig. 1984. Lampbrush loop-specific protein of Drosophila hydei. Proc. Natl. Acad. Sci. USA. 81:3404-3408.
22. Hurst, S.R., R.F. Hough, P.J. Aruscavage, and B.L. Bass. 1995. Deamination of mammalian glutamate receptor RNA by Xenopus dsRNA adenosine deaminase: similarities to in vivo RNA editing. RNA. 1:1051-1060.
23. Jantsch, M.F., and J.G. Gall. 1992. Assembly and localization of the U1-specific snRNP C protein in the amphibian oocyte. J. Cell Biol. 119:1037-1046.
24. Kim, U., Y. Wang, T. Sanford, and K. Nishikura. 1994. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc. Natl. Acad. Sci. USA. 91:11457-11461.
25. Kim, E., L. Du, D.B. Bregman, and S.L. Warren. 1997. Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA. J. Cell Biol. 136:19-28.
26. Kimelman, D., and M.W. Kirschner. 1989. An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes. Cell. 59:687-696.
27. Krainer, A. 1988. Pre-mRNA splicing by complementation with purified human U1, U2, U4/U6 and U5 snRNPs. Nucleic Acids Res. 16:9415-9429.
28. Lerner, E.A., M.R. Lerner, C.A. Janeway, and J.A. Steitz. 1981. Monoclonal antibodies to nucleic acid-containing cellular constituents: Probes for molecular biology and autoimmune disease. Proc. Natl. Acad. Sci. USA. 78:2737-2741.
29. Lomeli, H., J. Mosbacher, T. Melcher, T. Höger, J.R.P. Geiger, T. Kuner, H. Monyer, M. Higuchi, A. Bach, and P.H. Seeburg. 1994. Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science. 266:1709-1713.
30. Melcher, T., S. Maas, A. Herb, R. Sprengel, P.H. Seeburg, and M. Higuchi. 1996. A mammalian RNA editing enzyme. Nature. 379:460-464.
31. O'Connell, M.A. 1997. RNA editing: rewriting receptors. Curr. Biol. 7:R437-439.
32. O'Connell, M.A., S. Krause, M. Higuchi, J.J. Hsuan, N.F. Totty, A. Jenny, and W. Keller. 1995. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell. Biol. 15:5376-5388.
33. O'Connell, M.A., A. Gerber, and W. Keller. 1997. Purification of human double-stranded RNA-specific editase 1 (hRED1) involved in editing of brain glutamate receptor B pre-mRNA. J. Biol. Chem. 272:473-478.
34. Pan, Z.-Q., and C. Prives. 1988. Assembly of functional U1 and U2 human-amphibian hybrid snRNPs in Xenopus laevis oocytes. Science. 241:1328-1331.
35. Patterson, J.B., and C.E. Samuel. 1995. Expression and regulation by interferon of a double-stranded RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase. Mol. Cell. Biol. 15:5376-5388.
36. Paul, M.S., and B.L. Bass. 1998. Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA. EMBO (Eur. Mol. Biol. Organ.) J. 17: 1120-1127.
37. Peculis, B.A., and J.G. Gall. 1992. Localization of the nucleolar protein NO38 in amphibian oocytes. J Cell Biol. 116:1-14.
38. Petschek, J.P., M.R. Scheckelhoff, M.J. Mermer, and J.C. Vaughn. 1997. RNA editing and alternative splicing generate mRNA transcript diversity for the Drosophila 4f-rnp locus. Gene. 204:267-276.
39. Polson, A.G., and B.L. Bass. 1994. Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase. EMBO (Eur. Mol. Biol. Organ.) J. 13:5701-5711.
40. Polson, A.G., B.L. Bass, and J.L. Casey. 1996. RNA editing of hepatitis delta virus antigenome by dsRNA adenosine deaminase. Nature. 380:454-456.
41. Polson, A.G., P.F. Crain, S.C. Pomerantz, J.A. McCloskey, and B.L. Bass. 1991. The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high performance liquid chromatography-mass spectrometry analysis. Biochemistry. 30:11507-11514.
42. Rebagliati, M.R., and D.A. Melton. 1987. Antisense RNA injections into fertilized frog eggs reveal an RNA duplex unwinding activity. Cell. 48:599-605.
43. Sommer, B., M. Köhler, R. Sprengel, and P.H. Seeburg. 1991. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 67:11-19.
44. St Johnston, D., N.H. Brown, J.G. Gall, and M. Jantsch. 1992. A conserved double-stranded RNA-binding domain. Proc. Natl. Acad. Sci. USA. 89:10979-10983.
45. Tsvetkov, A., M. Jantsch, Z. Wu, C. Murphy, and J.G. Gall. 1992. Transcription on lamphrush chromosome loops in the absence of U2 snRNA. Mol. Biol. Cell. 3:249-261.
46. Vincent, M., P. Lauriault, M.-F. Dubois, S. Lavoie, O. Bonsaude, and B. Chabot. 1996. The nuclear matrix protein p255 is a highly phosphorylated form of RNA polymerase II largest subunit which associates with spliceosomes. Nucleic Acids Res. 24:4649-4652.
47. Visa, N., E. Izaurralde, J. Ferreira, B. Daneholt, and I.W. Mattaj. 1996. A nuclear cap-binding complex hinds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export. J. Cell Biol. 133:5-14.
48. Wu, Z., C. Murphy, H.G. Callan, and J.G. Gall. 1991. Small nuclear ribonucleoproteins and heterogeneous nuclear ribonucleoproteins in the amphibian germinal vesicle: loops, spheres and snurposomes. J. Cell Biol. 113:465-483.
49. Yang, J.-H., P. Sklar, R. Axel, and T. Maniatis. 1995. Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosines. Nature: 374:77-81.