Molecular cloning of human GABA(B)R1 and its tissue distribution

Molecular Brain Research

Volumn 64, Issue 1, 1999, Pages 137-140

  Makoff, Andrew ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Brain specific; cDNA clone; GABA(B) receptor; Signal sequence

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; BRAIN; CONTROLLED STUDY; GENE ISOLATION; HEART; HUMAN; HUMAN TISSUE; KIDNEY; LIVER; LUNG; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PLACENTA; PRIORITY JOURNAL; SKELETAL MUSCLE; TISSUE DISTRIBUTION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, NORTHERN; BRAIN CHEMISTRY; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, GABA-B; RNA, MESSENGER; SPINAL CORD;

EID: 0033593580     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00316-7     Document Type: Article

References (11)

1. N.G. Bowery, A. Doble, D.R. Hill, A.L. Hudson, J.S. Shaw, M.J. Turnbull, R. Warrington, Bicuculline-insensitive GABA receptors on peripheral autonomie nerve terminals, Eur. J. Pharmacol. 71 (1981) 53-70.
2. N.G. Bowery, D.I.B. Kerr, J. Ong, GABAB receptors - role and therapeutic implications in CNS disorders, CNS Drugs 7 (1997) 167-175.
3. E. Hosli, P. Krogsgaard Larsen, L. Hosli, Autoradiographic localization of binding sites for the gamma-aminobutyric acid analogues 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP)isoguvacine and baclofen on cultured neurons of rat cerebellum and spinal cord, Neurosci. Lett. 61 (1985) 153-157.
4. G.A. Johnston, GABAc receptors: relatively simple transmitter-gated ion channels?, Trends. Pharmacol. Sci. 17 (1996) 319-323.
5. K. Kaupmann, K. Huggel, J. Heid, P.J. Flor, S. Bischoff, S.J. Mickel, G. McMaster, C. Angst, H. Bittiger, W. Froestl, B. Bettler, Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors, Nature 386 (1997) 239-246.
6. A. Makoff, R. Lelchuk, M. Oxer, K. Harrington, P. Emson, Molecular characterization and localization of human metabotropic glutamate receptor type 4, Mol. Brain Res. 37 (1996) 239-248.
7. M. Malcangio, N.G. Bowery, Gamma-aminobutyric acid B, but not gamma-aminobutyric acid A receptor activation, inhibits electrically evoked substance P-like immunoreactivity release from the rat spinal cord in vitro, J. Pharmacol. Exp. Ther. 266 (1993) 1490-1496.
8. H. Nielsen, J. Engelbrecht, S. Brunak, G. von Heijne, Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites, Protein Eng. 10 (1997) 1-6.
9. J. Ong, D.I. Kerr, GABAA- and GABAB-receptor-mediated modification of intestinal motility, Eur. J. Pharmacol. 86 (1982) 9-17.
10. G.B. Smith, R.W. Olsen, Functional domains of GABAA receptors, Trends. Pharmacol. Sci. 16 (1995) 162-168.
11. G. von Heijne, A new method for predicting signal sequence cleavage sites, Nucleic Acids. Res. 14 (1986) 4683-4690.