Impaired movement control in Alzheimer's disease

Neuroscience Letters

Volumn 260, Issue 1, 1999, Pages 45-48

  Ghilardi, M Felice ^a,b   Alberoni, Margherita ^c   Marelli, Sabrina ^a   Rossi, Marina ^a   Franceschi, Massimo ^a   Ghez, Claude ^b   Fazio, Ferruccio ^a  

^a CNR   (Italy)

^b Howard Hughes Medical Institute   (United States)

^c IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

Alzheimer's disease; Bradykinesia; Humans; Kinematics; Reaching movements

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; ATTENTION; BIOMECHANICS; BRADYKINESIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEEDBACK SYSTEM; FEMALE; HUMAN; MALE; MOTOR CONTROL; PRIORITY JOURNAL; SPATIAL MEMORY; VISUAL MEMORY; WORKING MEMORY;

ALZHEIMER DISEASE; HUMANS; MOVEMENT;

EID: 0033593411     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00957-4     Document Type: Article

References (20)

1. Allamanno N., Della Sala S., Laiacona M., Pasetti C., Spinnler H. Problem solving ability in aging and dementia: normative data on a non-verbal test. Int. J. Neurol. Sci. 8:1987;111-120.
2. Alexander N.B., Mollo J.M., Giordani B., Ashton-Miller J.A., Schultz A.B., Grunawalt J.A., Foster N.L. Maintenance of balance, gait patterns, and ostacle clearance in Alzheimer's disease. Neurology. 45:1995;908-914.
3. Basso, A., Capitani, E. and Laiacona, M., Raven's coloured progressive matrices: normative values on 305 adult normal controls, Func. Neurol., (1987) 2 189-194.
4. Bellgrove M.A., Phillips J.G., Bradshaw J.L., Hall K.A., Presnell I., Hecht H. Response programming in dementia of the Alzheimer type: a kinematic analysis. Neuropsychologia. 35:1997;229-240.
5. Benton, A., Hamsher, K., Varney, N.R. and Spreen, O., Contribution to Neuropsychological Assessment, Oxford University Press, New York, 1983.
6. Buchner D.M., Larson E.B. Falls and fractures in patients with Alzheimer-type dementia. J. Am. Med. Assoc. 257:1987;1492-1495.
7. Folstein M.F., Folstein S.E., McHugh P.R. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J. Psychiat. Res. 12:1975;189-198.
8. Foster N.L., Chase T.N., Mansi L., Brooks R., Fedio P., Patronas N.J., Di Chiro G. Cortical abnormalities in Alzheimer's disease. Ann. Neurol. 16:1984;649-654.
9. Freund, H.J., What is the evidence for multiple motor areas in the human brain? In D.R. Humphrey and H.-J. Freund (Eds.), Motor Control: Concepts and Issues, John Wiley, Chichester, 1991, pp. 399-411.
10. Ghilardi M.F., Gordon J., Ghez C. Learning a visuomotor transformation in a local area of workspace produces directional biases in other areas. J. Neurophysiol. 73:1995;2535-2539.
11. Gordon J., Ghilardi M.F., Ghez C. Accuracy of planar reaching movements. I. Independence of direction and extent variability. Exp. Brain Res. 99:1994;97-111.
12. Gordon J., Ghilardi M.F., Cooper S.E., Ghez C. Accuracy of planar reaching movements. II. Systematic extent errors resulting from inertial anisotropy. Exp. Brain Res. 99:1994;112-130.
13. Jagacinski, R.J., Target acquisition: performance measures., process models and design applications. In G.R. McMillan (Ed.), Applications of Human Performance Models to System Design, Plenum Press, New York, 1989, pp. 135-149.
14. Koller W., Wilson R., Glatt S.L., Fox J. Motor signs are infrequent in dementia of the Alzheimer type. Ann. Neurol. 16:1984;514-516.
15. McCarthy G., Blamire A.M., Puce A., Nobre A.C., Bloch G., Hyder F., Goldman-Rakic P., Shulman R.G. Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task. Proc. Natl. Acad. Sci. USA. 91:1994;8690-8694.
16. Mc Khann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 34:1984;939-944.
17. Muller G., Richter R.A., Weisbrod S., Klingberg F. Reaction time prolongation in the early stage of presenile onset Alzheimer's disease. Eur. Arch. Psychiat. Clin. Neurosci. 241:1991;46-48.
18. Ott B.R., Ellias S.A., Lannon M.C. Quantitative assessment of movement in Alzheimer's disease. J. Geriatr. Psychiat. Neurol. 8:1995;71-75.
19. Sainburg R.L., Ghilardi M.F., Poizner H., Ghez C. Role of proprioceptive input in the control of interaction torques during multijoint arm movements. J. Neurophysiol. 73:1995;820-835.
20. Woodworth R.S. The accuracy of voluntary movements. Psychol. Rev. 3:1899;1-114.