Palladium-catalyzed asymmetric alkylation of ketone enolates [7]

Journal of the American Chemical Society

Volumn 121, Issue 28, 1999, Pages 6759-6760

  Trost, Barry M ^a   Schroeder, Gretchen M ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KETONE; PALLADIUM;

ALKYLATION; CATALYSIS; CHEMICAL STRUCTURE; CHIRALITY; LETTER; REACTION ANALYSIS; STOICHIOMETRY;

EID: 0033591944     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja991135b     Document Type: Letter

References (31)

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22. This assignment required hydroboration-oxidation of the alkene and ketone reduction to produce diastereomeric diols whose relative and absolute stereochemistry were established by NMR methods. Details appear in the Supporting Information.
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31. After submission of this manuscript, the report of the alkylation of the lithium enolate of 2-substituted tetralones generated from enol silyl ethers using chiral amine inducers appeared, see: Yamashita, Y.; Odashima, K.; Koga, K. Tetrahedron Lett. 1999, 40, 2803.