Stereochemical preference for heterochiral coupling controls selectivity in competitive peptide synthesis

Chemical Communications

Volumn , Issue 10, 1999, Pages 941-942

  Birch, David ^a   Hill, Roger R ^b   Jeffs, G E ^b   North, Michael ^a  

^a BANGOR UNIVERSITY   (United Kingdom)

^b OPEN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; AMINO ACID MIXTURE; PEPTIDE;

ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; CONTROLLED STUDY; STEREOCHEMISTRY;

EID: 0033591365     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/a901730e     Document Type: Article

References (12)

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2. S. A. Kaufman, The Origins of Order, OUP, Oxford, 1993; B. M. Rode, J. Phys. Chem., 1992, 96, 4170; A. Brack, Origins Life, 1987, 17, 367; K. Dose, Naturwissenschaften, 1983, 70, 378.
3. S. A. Kaufman, The Origins of Order, OUP, Oxford, 1993; B. M. Rode, J. Phys. Chem., 1992, 96, 4170; A. Brack, Origins Life, 1987, 17, 367; K. Dose, Naturwissenschaften, 1983, 70, 378.
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8. S. W. Fox and K. Dose, Molecular Evolution and the Origin of Life, Dekker, New York, 1974.
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10. M. Bodansky and A. Bodansky, The Practice of Peptide Synthesis, Springer-Verlag, Berlin, 1984.
11. Authentic standards for each coupling experiment were prepared by reaction between a single N-phthaloyl amino acid and a single amino acid dimethyl amide, and gave satisfactory spectroscopic and analytical data.
12. S. Tyagi and C. Pomamperuma, J. Mol. Evol., 1990, 30, 391.