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Volumn 40, Issue 21, 1999, Pages 4069-4072

A convenient synthesis of highly substituted 2-pyridones

Author keywords

Coupling reactions; Pyridones; Vilsmeier reactions reagents

Indexed keywords

3 TRIFLUOROMETHANE SULFONYLOXY 2 PYRIDONE; DIPYRONE; UNCLASSIFIED DRUG;

EID: 0033591158     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00651-6     Document Type: Article
Times cited : (29)

References (29)
  • 1
    • 84944031181 scopus 로고    scopus 로고
    • Katritzky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon Press
    • 1. For a review see Balasubramanian, M; Keay, J. G. in Comprehensive Heterocyclic Chemistry II; Katritzky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon Press, 1996, 5, pp 245-300.
    • (1996) Comprehensive Heterocyclic Chemistry II , vol.5 , pp. 245-300
    • Balasubramanian, M.1    Keay, J.G.2
  • 12
    • 0013556540 scopus 로고    scopus 로고
    • see following paper in this issue
    • 7. Nadin, A.; Harrison, T. see following paper in this issue.
    • Nadin, A.1    Harrison, T.2
  • 13
    • 0001426452 scopus 로고
    • 8. For reviews see (a) Meth-Cohn, O. Heterocycles, 1993, 35, 539-557.
    • (1993) Heterocycles , vol.35 , pp. 539-557
    • Meth-Cohn, O.1
  • 19
    • 0013491571 scopus 로고    scopus 로고
    • note
    • 13. This can be considered as the result of the reaction of 6 with two equivalents of the Vilsmeier reagent to give aminomethylenation of the enamine functionality and chlorination of the amide. Ring closure and elimination of dimethylamine generates the 1-methyl-2-chloro-3-benzyloxy-5,6-diarylpyridinium species.
  • 21
    • 0013519966 scopus 로고    scopus 로고
    • note
    • 4), filtered and concentrated. The products were triturated as necessary to give solid material which was of purity 95-99% as measured by hplc.
  • 29
    • 0013559882 scopus 로고    scopus 로고
    • note
    • 1H NMR and MS data.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.