The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling

Journal of Biological Chemistry

Volumn 274, Issue 34, 1999, Pages 23707-23718

  Hayes, Jonathan S ^a   Lawler, Orlaith A ^a   Walsh, Marie Therese ^a   Kinsella, B Therese ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CICAPROST; CYCLIC AMP; CYSTEINE; ILOPROST; PHOSPHOLIPASE C; PROSTACYCLIN RECEPTOR; SERINE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ISOPRENYLATION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS;

ADENYLATE CYCLASE; ANIMALS; BASE SEQUENCE; CALCIUM; CYCLIC AMP; HUMANS; ILOPROST; LOVASTATIN; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASE C; POLYISOPRENYL PHOSPHATES; PROTEIN ISOPRENYLATION; RECEPTORS, EPOPROSTENOL; RECEPTORS, PROSTAGLANDIN; STRUCTURE-ACTIVITY RELATIONSHIP;

IPS;

EID: 0033588290     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.34.23707     Document Type: Article

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