Synthesis of C-4 substituted pyrimidines exhibiting various H-bonding patterns

Tetrahedron Letters

Volumn 40, Issue 34, 1999, Pages 6229-6232

  Blanalt Feidt, Stéphanie ^a   Doronina, Svetlana O ^a   Behr, Jean Paul ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Amidines; Hydrogen bonding; Nucleosides; Pyrimidines

Indexed keywords

PYRIMIDINE DERIVATIVE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; HYDROLYSIS; ISOMERISM; POLYMERIZATION; REACTION ANALYSIS; STEREOSPECIFICITY; X RAY CRYSTALLOGRAPHY;

EID: 0033588234     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01163-6     Document Type: Article

References (13)

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12. -1. Crystal dimensions: 0.20x0.14x0.10 mm. Data were measured at 173 K on a Kappa CCD diffractometer with graphite monochromated Mo-Kα radiation. The structure was solved by direct methods using OpenMoleN 2.2 and refined anisotropically using absorption corrected data to give R=0.057, Rw=0.078 for 1806 independent observed reflections [Fo3σ(Fo)]. The 5′-OH group was disordered with two positions O(4) and O(5). Atomic coordinates, bond lengths and angles have been deposited at the Cambridge Crystallographic Data Centre.
13. 13C NMR spectra, mass spectra and elemental analyses.