Nuclear magnetic resonance and restrained molecular dynamics studies of the interaction of an epidermal growth factor-derived peptide with protein tyrosine phosphatase 1B

Biochemistry

Volumn 38, Issue 16, 1999, Pages 5256-5271

  Glover, Nicholas R ^a,b   Tracey, Alan S ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b University Medical Discoveries Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; ENZYME INHIBITOR; FLUORINE; GLUTAMIC ACID; LEUCINE; LYSINE; PROTEIN EGFR988; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ALANINE; ASPARTIC ACID; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; GLUTAMIC ACID; LEUCINE; LIGANDS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PHENYLALANINE; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTOR, EPIDERMAL GROWTH FACTOR; TEMPERATURE; THERMODYNAMICS;

EID: 0033586791     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9825450     Document Type: Article

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