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Volumn 819, Issue 1-2, 1999, Pages 65-74

Evaluation of glycine site antagonists of the NMDA receptor in global cerebral ischaemia

Author keywords

324; ACEA1021; Cerebral ischaemia; Gerbil; Glycine site antagonist; GV150526A; L 701; LY293558; Neuroprotection

Indexed keywords

3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 6,7 DICHLORO 5 NITRO 2,3 QUINOXALINEDIONE; 7 CHLORO 4 HYDROXY 3 (3 PHENOXYPHENYL) 2 QUINOLONE; AMPA RECEPTOR ANTAGONIST; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; DIZOCILPINE; GAVESTINEL; GLYCINE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT;

EID: 0033585872     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01329-8     Document Type: Article
Times cited : (40)

References (57)
  • 1
    • 0023856682 scopus 로고
    • The N-methyl-D-aspartate antagonist CGS 19755 and CPP reduce ischemic damage in gerbils
    • Boast C.A., Gerhardt S.C., Pastor G., Lehmann J., Ethienne P.E., Liebmann J. The N-methyl-D-aspartate antagonist CGS 19755 and CPP reduce ischemic damage in gerbils. Brain Res. 442:1988;345-348.
    • (1988) Brain Res. , vol.442 , pp. 345-348
    • Boast, C.A.1    Gerhardt, S.C.2    Pastor, G.3    Lehmann, J.4    Ethienne, P.E.5    Liebmann, J.6
  • 2
    • 0030739272 scopus 로고    scopus 로고
    • The glycine antagonist GV 150526A protects somatosenory evoked potentials and reduces the infarct area in the MCAO model of focal ischemia in the rat
    • Bordi F., Pietra C., Ziviani L., Reggiani A. The glycine antagonist GV 150526A protects somatosenory evoked potentials and reduces the infarct area in the MCAO model of focal ischemia in the rat. Exp. Neurol. 145:1997;425-433.
    • (1997) Exp. Neurol. , vol.145 , pp. 425-433
    • Bordi, F.1    Pietra, C.2    Ziviani, L.3    Reggiani, A.4
  • 4
    • 0028279015 scopus 로고
    • Neuroprotective effect of the AMPA receptor antagonist LY 293558 in focal ischemia in the cat
    • Bullock R., Graham D.I., Swanson S., McCulloch J. Neuroprotective effect of the AMPA receptor antagonist LY 293558 in focal ischemia in the cat. J. Cereb. Blood Flow Metab. 14:1994;466-471.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 466-471
    • Bullock, R.1    Graham, D.I.2    Swanson, S.3    McCulloch, J.4
  • 5
    • 0025603178 scopus 로고
    • Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion
    • Butcher S.P., Bullock R., Graham D.I., McCulloch J. Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke. 21:1990;1727-1733.
    • (1990) Stroke , vol.21 , pp. 1727-1733
    • Butcher, S.P.1    Bullock, R.2    Graham, D.I.3    McCulloch, J.4
  • 8
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists
    • Choi D.W., Koh J.-Y., Peters S. Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J. Neurosci. 8:1988;185-196.
    • (1988) J. Neurosci. , vol.8 , pp. 185-196
    • Choi, D.W.1    Koh, J.-Y.2    Peters, S.3
  • 9
    • 0024829451 scopus 로고
    • Excitatory amino acid receptors in the vertebrate central nervous system
    • Collingridge G.L., Lester R.A.J. Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacol. Rev. 40:1989;143-210.
    • (1989) Pharmacol. Rev. , vol.40 , pp. 143-210
    • Collingridge, G.L.1    Lester, R.A.J.2
  • 10
    • 0025542925 scopus 로고
    • The glycine site on the NMDA receptor: Pharmacology and involvement in NMDA receptor-mediated neurodegeneration
    • Foster A.C., Donald A.E., Willis C.L., Tridgett R., Kemp J.A., Priestley T. The glycine site on the NMDA receptor: pharmacology and involvement in NMDA receptor-mediated neurodegeneration. Adv. Exp. Med. Biol. 268:1990;93-100.
    • (1990) Adv. Exp. Med. Biol. , vol.268 , pp. 93-100
    • Foster, A.C.1    Donald, A.E.2    Willis, C.L.3    Tridgett, R.4    Kemp, J.A.5    Priestley, T.6
  • 11
    • 0023425239 scopus 로고
    • Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil
    • Gill R., Foster A.C., Woodruff G.N. Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil. J. Neurosci. 7:1987;3343-3349.
    • (1987) J. Neurosci. , vol.7 , pp. 3343-3349
    • Gill, R.1    Foster, A.C.2    Woodruff, G.N.3
  • 12
    • 0028500548 scopus 로고
    • The pharmacology of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate antagonists and their role in cerebral ischaemia
    • Gill R. The pharmacology of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate antagonists and their role in cerebral ischaemia. Cerebrovasc. Brain Metab. Rev. 6:1994;225-256.
    • (1994) Cerebrovasc. Brain Metab. Rev. , vol.6 , pp. 225-256
    • Gill, R.1
  • 13
    • 0028852625 scopus 로고
    • The neuroprotective effect of the glycine site antagonist 3R-(+)-cis-4-methyl-HA966 (L-687,414) in a rat model of focal ischaemia
    • Gill R., Hargreaves R.J., Kemp J.A. The neuroprotective effect of the glycine site antagonist 3R-(+)-cis-4-methyl-HA966 (L-687,414) in a rat model of focal ischaemia. J. Cereb. Blood Flow Metab. 15:1995;197-204.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 197-204
    • Gill, R.1    Hargreaves, R.J.2    Kemp, J.A.3
  • 14
    • 0028587095 scopus 로고
    • The neuroprotective effects of the decahydroisoquinoline, LY 215490; A novel AMPA antagonist in focal ischaemia
    • Gill R., Lodge D. The neuroprotective effects of the decahydroisoquinoline, LY 215490; a novel AMPA antagonist in focal ischaemia. Neuropharmacology. 33:1995;1529-1536.
    • (1995) Neuropharmacology , vol.33 , pp. 1529-1536
    • Gill, R.1    Lodge, D.2
  • 15
    • 0023723433 scopus 로고
    • Effect of ischemia on in vivo release of striatal dopamine, glutamate and gamma-aminobutyric acid studied by intracerebral microdialysis
    • Globus M.Y.-T., Busto R., Dietrich W.D., Martinez E., Valdes I., Ginsberg M.D. Effect of ischemia on in vivo release of striatal dopamine, glutamate and gamma-aminobutyric acid studied by intracerebral microdialysis. J. Neurochem. 51:1988;1455-1464.
    • (1988) J. Neurochem. , vol.51 , pp. 1455-1464
    • Globus, M.Y.-T.1    Busto, R.2    Dietrich, W.D.3    Martinez, E.4    Valdes, I.5    Ginsberg, M.D.6
  • 16
    • 0344365159 scopus 로고
    • Excitotoxicity: Interaction of neuroactive substances during prolonged focal ischemia in cats
    • in: J. Krieglstein, H. Oberpichler-Schwenk (Eds.)
    • R. Graf, W.-D. Heiss, K. Wienhard, R. Saito, J. Taguchi, K. Matsumoto, K. Hübel, G. Rosner, Excitotoxicity: interaction of neuroactive substances during prolonged focal ischemia in cats, in: J. Krieglstein, H. Oberpichler-Schwenk (Eds.), Pharmacology of Cerebral Ischemia, 1994, pp. 165-176.
    • (1994) Pharmacology of Cerebral Ischemia , pp. 165-176
    • Graf, R.1    Heiss, W.-D.2    Wienhard, K.3    Saito, R.4    Taguchi, J.5    Matsumoto, K.6    Hübel, K.7    Rosner, G.8
  • 17
    • 0029877967 scopus 로고    scopus 로고
    • A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia
    • Graham S.H., Chen J., Lan J.Q., Simon R.P. A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia. J. Pharmacol. Exp. Ther. 276:1996;1-4.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 1-4
    • Graham, S.H.1    Chen, J.2    Lan, J.Q.3    Simon, R.P.4
  • 18
    • 0025351198 scopus 로고
    • CGS 19755, a competitive NMDA receptor antagonist, reduces calcium-calmodulin binding and improves outcome after global cerebral ischemia
    • Grotta J.C., Picone C.M., Ostrow P.T., Strong R.A., Earls R.M., Yao L.P., Rhoades, Dedman J.R. CGS 19755, a competitive NMDA receptor antagonist, reduces calcium-calmodulin binding and improves outcome after global cerebral ischemia. Ann. Neurol. 27:1990;612-619.
    • (1990) Ann. Neurol. , vol.27 , pp. 612-619
    • Grotta, J.C.1    Picone, C.M.2    Ostrow, P.T.3    Strong, R.A.4    Earls, R.M.5    Yao, L.P.6    Rhoades7    Dedman, J.R.8
  • 19
    • 0027294037 scopus 로고
    • Lack of effect of L-687,414 ((+)-cis-4-methyl-HA-966, an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology
    • Hargreaves R.J., Rigby M., Smith D., Hill R.G. Lack of effect of L-687,414 ((+)-cis-4-methyl-HA-966, an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology. Br. J. Pharmacol. 110:1993;36-42.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 36-42
    • Hargreaves, R.J.1    Rigby, M.2    Smith, D.3    Hill, R.G.4
  • 20
    • 0031023451 scopus 로고    scopus 로고
    • The N-methyl-D-aspartate (NMDA) receptor glycine site antagonist ACEA 1021 does not produce pathological changes in rat brain
    • Hawkinson J.E., Huber K.R., Sahota P.S., Han-Hsu H., Weber E., Whitehouse M.J. The N-methyl-D-aspartate (NMDA) receptor glycine site antagonist ACEA 1021 does not produce pathological changes in rat brain. Brain Res. 744:1997;227-234.
    • (1997) Brain Res. , vol.744 , pp. 227-234
    • Hawkinson, J.E.1    Huber, K.R.2    Sahota, P.S.3    Han-Hsu, H.4    Weber, E.5    Whitehouse, M.J.6
  • 21
    • 0030846837 scopus 로고    scopus 로고
    • Neuroprotective effect of YM90K, an AMPA-receptor antagonist, against delayed neuronal death induced by transient global cerebral ischemia in gerbils and rats
    • Kawasaki-Yatsugi S., Yatsugi S., Koshiya K., Shimizu-Sasamata M. Neuroprotective effect of YM90K, an AMPA-receptor antagonist, against delayed neuronal death induced by transient global cerebral ischemia in gerbils and rats. Jpn. J. Pharmacol. 74:1997;253-260.
    • (1997) Jpn. J. Pharmacol. , vol.74 , pp. 253-260
    • Kawasaki-Yatsugi, S.1    Yatsugi, S.2    Koshiya, K.3    Shimizu-Sasamata, M.4
  • 22
    • 0025819188 scopus 로고
    • Effects of (+) HA-966 and 7-chlorokynurenic acid on the kinetics of N-methyl-D-aspartate receptor agonist responses in rat cortical neurons
    • Kemp J.A., Priestley T. Effects of (+) HA-966 and 7-chlorokynurenic acid on the kinetics of N-methyl-D-aspartate receptor agonist responses in rat cortical neurons. Mol. Pharmacol. 39:1991;666-670.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 666-670
    • Kemp, J.A.1    Priestley, T.2
  • 23
    • 0027469106 scopus 로고
    • The glycine site of the NMDA receptor: Five years on
    • Kemp J.A., Leeson P.D. The glycine site of the NMDA receptor: five years on. Trends Pharmacol. Sci. 14:1993;20-25.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 20-25
    • Kemp, J.A.1    Leeson, P.D.2
  • 24
    • 0023901123 scopus 로고
    • MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
    • Koek W., Woods J.H., Winger G.D. MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys. J. Pharmacol. Exp. Ther. 245:1988;969-974.
    • (1988) J. Pharmacol. Exp. Ther. , vol.245 , pp. 969-974
    • Koek, W.1    Woods, J.H.2    Winger, G.D.3
  • 25
    • 0024396066 scopus 로고
    • Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use
    • Kurumaji A., Nehls D.G., Park C.K., McCulloch J. Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use. Brain Res. 496:1989;268-284.
    • (1989) Brain Res. , vol.496 , pp. 268-284
    • Kurumaji, A.1    Nehls, D.G.2    Park, C.K.3    McCulloch, J.4
  • 27
    • 0025740632 scopus 로고
    • Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor
    • Leeson P.D., Baker R., Carling R.W., Curtis N.R., Moore K.W., Williams B.J., Foster A.C., Donald A.E., Kemp J.A., Marshall G.R. Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor. J. Med. Chem. 34:1991;1243-1252.
    • (1991) J. Med. Chem. , vol.34 , pp. 1243-1252
    • Leeson, P.D.1    Baker, R.2    Carling, R.W.3    Curtis, N.R.4    Moore, K.W.5    Williams, B.J.6    Foster, A.C.7    Donald, A.E.8    Kemp, J.A.9    Marshall, G.R.10
  • 28
    • 0027445864 scopus 로고
    • Treatment with an AMPA antagonist 12 h following severe normothermic forebrain ischemia prevents CA1 neuronal injury
    • Li H., Buchan A.M. Treatment with an AMPA antagonist 12 h following severe normothermic forebrain ischemia prevents CA1 neuronal injury. J. Cereb. Blood Flow Metab. 13:1993;933-939.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 933-939
    • Li, H.1    Buchan, A.M.2
  • 29
    • 0030483662 scopus 로고    scopus 로고
    • Stereoselective effects of 2,3-benzodiazepines in vivo: Electrophysiology and neuroprotection studies
    • Lodge D., Bond A., O'Neill M.J., Hicks C.A., Jones M.G. Stereoselective effects of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies. Neuropharmacology. 35:1996;1681-1688.
    • (1996) Neuropharmacology , vol.35 , pp. 1681-1688
    • Lodge, D.1    Bond, A.2    O'Neill, M.J.3    Hicks, C.A.4    Jones, M.G.5
  • 30
    • 0026701712 scopus 로고
    • Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man
    • McCulloch J. Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man. Br. J. Clin. Pharmacol. 34:1992;106-114.
    • (1992) Br. J. Clin. Pharmacol. , vol.34 , pp. 106-114
    • McCulloch, J.1
  • 31
    • 0025063609 scopus 로고
    • Excitatory amino acids in neurotoxicity and neurodegenerative diseases
    • Meldrum B., Garthwaite J. Excitatory amino acids in neurotoxicity and neurodegenerative diseases. Trends Pharmacol. Sci. 11:1990;379-386.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 379-386
    • Meldrum, B.1    Garthwaite, J.2
  • 32
    • 0031965072 scopus 로고    scopus 로고
    • Effects of NMDA receptor glycine recognition site antagonism on cerebral metabolic rate for glucose and cerebral blood flow in the conscious rat
    • Morimoto Y., Wu B., Bart R.D., Morimoto Y., Pearlstein R.D., Warner D.S. Effects of NMDA receptor glycine recognition site antagonism on cerebral metabolic rate for glucose and cerebral blood flow in the conscious rat. Brain Res. 779:1998;170-176.
    • (1998) Brain Res. , vol.779 , pp. 170-176
    • Morimoto, Y.1    Wu, B.2    Bart, R.D.3    Morimoto, Y.4    Pearlstein, R.D.5    Warner, D.S.6
  • 33
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • Morris R.G.M., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature. 319:1986;774-0776.
    • (1986) Nature , vol.319 , pp. 774-0776
    • Morris, R.G.M.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 34
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phenyclidine and related drugs
    • Olney J.W., Labruyere J., Price M.T. Pathological changes induced in cerebrocortical neurons by phenyclidine and related drugs. Science. 244:1990;1360-1362.
    • (1990) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 37
    • 0030806308 scopus 로고    scopus 로고
    • Neuroprotective effects of the antioxidant LY231617 and NO synthase inhibitors in global cerebral ischaemia
    • O'Neill M.J., Hicks C., Ward M., Panetta J.A. Neuroprotective effects of the antioxidant LY231617 and NO synthase inhibitors in global cerebral ischaemia. Brain Res. 760:1997;170-178.
    • (1997) Brain Res. , vol.760 , pp. 170-178
    • O'Neill, M.J.1    Hicks, C.2    Ward, M.3    Panetta, J.A.4
  • 38
    • 0032191984 scopus 로고    scopus 로고
    • Decahydroisoquinolines: Novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia
    • O'Neill M.J., Bond A., Ornstein P.L., Ward M.A., Hicks C.A., Hoo K., Bleakman D., Lodge D. Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia. Neuropharmacol. 37:1998;1211-1222.
    • (1998) Neuropharmacol. , vol.37 , pp. 1211-1222
    • O'Neill, M.J.1    Bond, A.2    Ornstein, P.L.3    Ward, M.A.4    Hicks, C.A.5    Hoo, K.6    Bleakman, D.7    Lodge, D.8
  • 39
    • 0026491225 scopus 로고
    • Efficacy of D-CPPene, a competitive N-methyl-D-aspartate antagonist in focal cerebral ischemia in the rat
    • Park C.K., McCulloch J., Kang J.K., Choi C.R. Efficacy of D-CPPene, a competitive N-methyl-D-aspartate antagonist in focal cerebral ischemia in the rat. Neurosci. Lett. 147:1992;41-44.
    • (1992) Neurosci. Lett. , vol.147 , pp. 41-44
    • Park, C.K.1    McCulloch, J.2    Kang, J.K.3    Choi, C.R.4
  • 41
    • 0031959128 scopus 로고    scopus 로고
    • Neuroprotective effects of NMDA receptor glycine recognition sites antagonism: Dependence on glycine concentration
    • Pearlstein R.D., Beirne J.P., Massey G.W., Warner D.S. Neuroprotective effects of NMDA receptor glycine recognition sites antagonism: dependence on glycine concentration. J. Neurochem. 70:1998;2012-2019.
    • (1998) J. Neurochem. , vol.70 , pp. 2012-2019
    • Pearlstein, R.D.1    Beirne, J.P.2    Massey, G.W.3    Warner, D.S.4
  • 42
    • 0028099925 scopus 로고
    • The glycine antagonist and free radical scavenger 7-Cl-thio-kynurate reduces CA1 ischemic damage in the gerbil
    • Pelligrini-Giampietro D.E., Cozzi A., Moroni F. The glycine antagonist and free radical scavenger 7-Cl-thio-kynurate reduces CA1 ischemic damage in the gerbil. Neuroscience. 63:1994;701-709.
    • (1994) Neuroscience , vol.63 , pp. 701-709
    • Pelligrini-Giampietro, D.E.1    Cozzi, A.2    Moroni, F.3
  • 43
    • 0025012027 scopus 로고
    • The effect of NMDA receptor glycine site antagonists on hypoxia-induced neurodegeneration of rat cortical cell cultures
    • Priestley T., Horne A.L., McKernan R.M., Kemp J.A. The effect of NMDA receptor glycine site antagonists on hypoxia-induced neurodegeneration of rat cortical cell cultures. Brain Res. 53:1990;183-188.
    • (1990) Brain Res. , vol.53 , pp. 183-188
    • Priestley, T.1    Horne, A.L.2    McKernan, R.M.3    Kemp, J.A.4
  • 45
    • 0025117827 scopus 로고
    • 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline: A neuro-protectant for cerebral ischemia
    • Sheardown M.J., Nielson E.O., Hansen A.J., Jacobsen P., Honoré T. 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline: a neuro-protectant for cerebral ischemia. Science. 247:1990;571-574.
    • (1990) Science , vol.247 , pp. 571-574
    • Sheardown, M.J.1    Nielson, E.O.2    Hansen, A.J.3    Jacobsen, P.4    Honoré, T.5
  • 46
    • 0027336469 scopus 로고
    • AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia
    • Sheardown M.J., Suzdak P.D., Nordholm L. AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia. Eur. J. Pharmacol. 236:1993;347-353.
    • (1993) Eur. J. Pharmacol. , vol.236 , pp. 347-353
    • Sheardown, M.J.1    Suzdak, P.D.2    Nordholm, L.3
  • 48
    • 0026623418 scopus 로고
    • Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat
    • Smith S.E., Meldrum B.S. Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat. Stroke. 23:1992;861-864.
    • (1992) Stroke , vol.23 , pp. 861-864
    • Smith, S.E.1    Meldrum, B.S.2
  • 50
    • 0030704290 scopus 로고    scopus 로고
    • Neuroprotective effect of a novel AMPA receptor antagonist, YM90K, in rat focal cerebral ischaemia
    • Umemura K., Shimakura A., Nakashima M. Neuroprotective effect of a novel AMPA receptor antagonist, YM90K, in rat focal cerebral ischaemia. Brain Res. 773:1997;61-65.
    • (1997) Brain Res. , vol.773 , pp. 61-65
    • Umemura, K.1    Shimakura, A.2    Nakashima, M.3
  • 51
    • 0037841176 scopus 로고    scopus 로고
    • B receptor antagonists in the amygdala-kindling model in rats
    • B receptor antagonists in the amygdala-kindling model in rats. Eur. J. Pharmacol. 342:1998;39-46.
    • (1998) Eur. J. Pharmacol. , vol.342 , pp. 39-46
    • Wlaz, P.1    Löscher, W.2
  • 52
    • 0028834171 scopus 로고
    • In vivo models of cerebral ischemia: Effects of parentally administered NMDA receptor glycine site antagonists
    • Warner D.S., Martin H., Ludwig P., McAllister A., Keana Jt.F.W., Weber E. In vivo models of cerebral ischemia: effects of parentally administered NMDA receptor glycine site antagonists. J. Cereb. Blood Flow Metab. 15:1995;188-196.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 188-196
    • Warner, D.S.1    Martin, H.2    Ludwig, P.3    McAllister, A.4    Keana, Jt.f.w.5    Weber, E.6
  • 53
    • 0023182317 scopus 로고
    • Agonists and antagonists for excitatory amino acid receptors
    • Watkins J.C., Olverman H.J. Agonists and antagonists for excitatory amino acid receptors. Trends Neurosci. 10:1987;265-272.
    • (1987) Trends Neurosci. , vol.10 , pp. 265-272
    • Watkins, J.C.1    Olverman, H.J.2
  • 54
    • 0026757526 scopus 로고
    • A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo
    • Wood E.R., Bussey T.J., Phillips A.G. A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo. Neurosci. Lett. 145:1992;10-14.
    • (1992) Neurosci. Lett. , vol.145 , pp. 10-14
    • Wood, E.R.1    Bussey, T.J.2    Phillips, A.G.3
  • 55
    • 0027414756 scopus 로고
    • A glycine antagonist 7-chlorokynurenic acid attenuates ischemia-induced learning deficits
    • Wood E.R., Bussey T.J., Phillips A.G. A glycine antagonist 7-chlorokynurenic acid attenuates ischemia-induced learning deficits. NeuroReport. 4:1993;151-154.
    • (1993) NeuroReport , vol.4 , pp. 151-154
    • Wood, E.R.1    Bussey, T.J.2    Phillips, A.G.3


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