Effect of ketamine on hypoxic-ischemic brain damage in newborn rats

Brain Research

Volumn 819, Issue 1-2, 1999, Pages 1-7

  Spandou, Evangelia ^a   Karkavelas, George ^a   Soubasi, Vassiliki ^a   Avgovstides Savvopoulou, Persephone ^a   Loizidis, Theodoros ^a   Guiba Tziampiri, Olympia ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Hippocampus; Hypoxia; Ischemia; Ketamine; Neonatal; Rat

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; GLUTAMIC ACID; GLUTAMINE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEMISPHERE; HIGH ENERGY PHOSPHATE; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NERVE CELL LESION; NEUROPATHOLOGY; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; BRAIN; BRAIN ISCHEMIA; CAROTID ARTERY DISEASES; FEMALE; FUNCTIONAL LATERALITY; GLUTAMIC ACID; GLUTAMINE; HYPOXIA, BRAIN; KETAMINE; MALE; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHOCREATINE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0033585870     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01333-X     Document Type: Article

References (37)

1. Andiné P., Sandberg M., Bagenholm R., Lehmann A., Hagberg H. Intra- and extracellular changes of amino acids in the cerebral cortex of the neonatal rat during hypoxic-ischemia. Dev. Brain Res. 64:1991;115-120.
2. Anis N.A., Berry T., Burton N.R., Lodge D. The dissociative anaesthetics ketamine and phencyclidine selectively reduce excitation of central mammalian neurones by N-methyl-D-aspartate. Br. J. Pharmacol. 79:1983;565-575.
3. Bielenberg G.W., Beck T., Sauer D., Burniol M., Krieglstein J. Effects of cerebroprotective agents on cerebral blood flow and on postischemic energy metabolism in the rat brain. J. Cereb. Blood Flow Metab. 7:1987;480-488.
4. Cavazzuti M., Porro C.A., Biral G.P., Benassi C., Barbieri G.C. Ketamine effects on local cerebral blood flow and metabolism in the rat. J. Cereb. Blood Flow Metab. 7:1987;806-811.
5. Chan P.H., Chu L. Ketamine protects cultured astrocytes from glutamate-induced swelling. Brain Res. 487:1989;380-383.
6. Church J., Zeman S., Lodge D. The neuroprotective action of ketamine and MK-801 after transient cerebral ischemia in rats. Anesthesiology. 69:1988;702-709.
7. Church J., Zeman S. Ketamine promotes hippocampal CA1 pyramidal neuron loss after a short-duration ischemic insult in rats. Neurosci. Lett. 123:1991;65-68.
8. Crosby G., Crane A.M., Sokoloff L. Local changes in cerebral glucose utilization during ketamine anesthesia. Anesthesiology. 56:1982;437-443.
9. Davies S.N., Martin D., Millar J.D., Aram J.A., Church J., Lodge D. Differences in results from in vivo and in vitro studies on the use-dependency of N-methylaspartate antagonism by MK-801 and other phencyclidine receptor ligands. Eur. J. Pharmacol. 43:1988;141-151.
10. Davis D.W., Mans A.M., Biebuck J.F., Hawkins R.A. Regional cerebral glucose utilization during ketamine anesthesia. Soc. Neurosci. Abstr. 11:1985;1261.
11. Delivoria-Papadopoulos M., Mishra O.P. Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention. J. Pediatr. (Suppl.). 132:1998;S30-S34.
12. du Plessis A.J., Johnston M.V. Hypoxic-ischemic brain injury in the newborn. Cellular mechanisms and potential strategies for neuroprotection. Clinics in Perinatology. 24:1997;627-654.
13. + efflux and neurotransmitter amino acid release. Br. J. Pharmacol. 94:1988;871-881.
14. Fritz K.I., Groenendaal F., McGowan J.E., Mishra O.P., Delivoria-Papadopoulos M. Effect of cerebral hypoxia on NMDA receptor binding characteristics after treatment with 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) in newborn piglets. Brain Res. 729:1996;66-74.
15. Hammer R.P., Herkenham M. Altered metabolic activity in the cerebral cortex of rats exposed to ketamine. J. Comp. Neurol. 220:1983;396-404.
16. 4 infusion on NMDA receptor binding characteristics during cerebral cortical hypoxia in newborn piglets. Brain Res. 644:1994;144-149.
17. Holownia A., Chwiencko M., Farbiszewski R. Accumulation of ammonia and changes in the activity of some metabolizing enzymes during brain ischemia/reperfusion injury in rats. Mater. Med. Pol. 26:1994;25-27.
18. Keilhoff G., Wolf G., Stastny F. Effects of MK-801, ketamine and alaptide on quinolinate models in the maturing hippocampus. Neuroscience. 42:1991;379-385.
19. W. Lamprecht, Creatine phosphate, in: H.U. Bergmeyer, (Ed.), Methods of Enzymatic Analysis, Vol. 4, Academic Press, New York, NY, 1974, pp. 1777-1781.
20. Lees G.J. Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus. Neurosci. Lett. 78:1987;180-186.
21. Lees G.J. Influence of ketamine on the neuronal death caused by NMDA in the rat hippocampus. Neuropharmacology. 34:1995;411-417.
22. Jensen M.L., Auer R.N. Ketamine fails to protect against ischemic neuronal necrosis in the rat. Br. J. Anaesth. 61:1988;206-210.
23. Marcoux F.W., Goodrich J.E., Dominick M.A. Ketamine prevents ischemic neuronal injury. Brain Res. 452:1988;329-335.
24. McDonald J.W., Johnston M.V. Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res. Rev. 15:1990;41-70.
25. Newcomb R., Sun X., Taylor L., Curthoys N., Giffard R.G. Increased production of extracellular glutamate by the mitochondrial glutaminase following neuronal death. J. Biol. Chem. 272:1997;11276-11282.
26. Oliver C.N., Starke-Reed P.E., Stadtman E.R., Liu G.J., Carney J.M., Floyd R.A. Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. USA. 87:1990;5144-5147.
27. Pfenninger E., Himmelseher S. Neuroprotektion durch ketamin auf zellularer ebene. Anaesthesist. 46:1997;S47-S54. Suppl 1.
28. Pohorecki R., Becker G.L., Reilly P.J., Landers D.F. Ischemic brain injury in vitro: protective effects of NMDA receptor antagonists and calmidazolium. Brain Res. 528:1990;133-137.
29. Raley K.M., Lipton P. NMDA receptor activation accelerates ischemic energy depletion in the hippocampal slice and the demonstration of a threshold for ischemic damage to protein synthesis. Neurosci. Lett. 110:1990;118-123.
30. Rice J.E., Vannucci R.C., Brierley J.B. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann. Neurol. 9:1981;131-141.
31. Rothman S.M., Thurston J.H., Hauhart R.E., Clark J.D., Solomon J.S. Ketamine protects hippocampal neurons from anoxia in vitro. Neuroscience. 21:1987;673-678.
32. Schwedler M., Miletich D.J., Albrecht R.F. Cerebral blood flow and metabolism following ketamine administration. Can. Anaesth. Soc. J. 29:1982;222-225.
33. N.H. Sherwood, P.S. Timiras, A Stereotaxic Atlas of the Developing Rat Brain, Univ. of California Press, Berkeley, 1970.
34. Takeshita H., Okuda Y., Sari A. The effects of ketamine on cerebral circulation and metabolism in man. Anesthesiology. 36:1972;69-75.
35. Thomson A.M., West D.C., Lodge D. An N-methyl-D-aspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine? Nature. 313:1985;479-481.
36. Weiss J., Goldberg M.P., Choi D.W. Ketamine protects cultured neocortical neurons from hypoxic injury. Brain Res. 380:1986;186-190.
37. White P.F., Way W.L., Trevor A.J. Ketamine - its pharmacology and therapeutic uses. Anesthesiology. 56:1982;119-136.