Interferon-β-induced human immunodeficiency virus resistance in CD34+ human hematopoietic progenitor cells: Correlation with a down-regulation of CCR-5 expression

Virology

Volumn 253, Issue 2, 1999, Pages 241-249

  Cremer, Isabelle ^a   Vieillard, Vincent ^a   De Maeyer, Edward ^a  

^a INSTITUT D'OPTIQUE GRADUATE SCHOOL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CHEMOKINE RECEPTOR CCR5; RECOMBINANT ALPHA2B INTERFERON; RECOMBINANT BETA INTERFERON; VIRUS VECTOR;

ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HELPER CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; INTERFERON PRODUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; VIRUS RESISTANCE; VIRUS STRAIN;

HUMAN IMMUNODEFICIENCY VIRUS; RNA VIRUSES;

EID: 0033585366     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9470     Document Type: Article

References (48)

1. Aloia, R. C., Tian, H., and Jensen, F. C. (1993). Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membrane. Proc. Natl. Acad. Sci. USA 90, 5181-5185.
2. Asagoe, K., Yamamoto, K., Takahashi, A., Suzuki, K., Maeda, A., Nohgawa, M., Harakawa, N., Takano, K., Mukaida, N., Matsushima, K., Okuma, M., and Sasada, M. (1998). Down-regulation of CXCR2 expression on human polymorphonuclear leukocytes by TNF-α. J. Immunol. 160, 4518-4525.
3. Baca-Regen, L., Heinzinger, N., Stevenson, M., and Gendelman, H. E. (1994). Alpha interferon-induced antiretroviral activities: Restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes. J. Virol. 68, 7559- 7565.
4. + hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture. J. Virol. 70, 4352-4360.
5. Berger, E. A., Doms, R. W., Fenyo, E. M., Korber, B. T., Littman, D. R., Moore J. P., Sattentau, Q. J., Schuitemaker, H., Sodroski, J., and Weiss, R. A. (1998). A new classification for HIV-1 Nature 391, 240.
6. Bridges, S. H., and Sarver, N. (1995). Gene therapy and immune restoration for HIV disease. Lancet 345, 427-432.
7. Broxmeyer, H. E., Lu, L., Platzer, E., Feit, C., Juliano, L., and Rubin, B. Y. (1983). Comparative analysis of the influences of human gamma, alpha and beta interferons on human multipotential (CFU-GEMM), erythroid (BFU-E) and granulocyte-macrophage (CFU-GM) progenitor cells. J. Immunol. 131, 1300-1305.
8. Cairns, J. S., and D'Souza, M. P. (1998). Chemokines and HIV-1 second receptors: The therapeutic connection. Nature Med. 4, 563-568.
9. Chameau, P., Mirambeau, G., Roux, P., Paulous, S., Buc, H., and Clavel, F. (1994). HIV-1 reverse transcription: A termination step at the center of the genome. J. Mol. Biol. 241, 651-662.
10. Chelucci, C., Hassan, H. J., Locardi, C., Bulgarini, D., Pelosi, E., Mariani, G., Testa, U., Federico, M., Valtieri, M., and Peschle, C. (1995). In vitro human immunodeficiency virus-1 infection of purified hematopoietic progenitors in single-cell culture. Blood 85, 1181-1187.
11. Dean, M., Carrington, M., Winkler, C., Huttley, G. A., Smith, M. W., Allikmets, R., Goedert, J. J., Buchbinder, S. P., Vittinghoff, E., Gomperts, E., Donfield, S., Vlahov, D., Kaslow, R., Saah, A., Rinaldo, C., Detels, R., and O'Brien, S. J. (1996). Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science 273, 1856-1862.
12. + hematopoietic progenitor cells. Blood 89, 3522-3528.
13. De Maeyer, E., and De Maeyer-Guignard, J. (1988). "Interferons and Other Regulatory Cytokines." John Wiley and Sons Ltd., Chichester.
14. Donahue, R. E., Johnson, M. M., Zon, L. I., Clark, S. C., and Groopman, J. E. (1987). Suppression of in vitro haematopoiesis following human immunodeficiency virus infection. Nature 326, 200-203.
15. Francis, M. L., Meltzer, M. S., and Gendelman, H. E. (1992). Interferons in the persistence, pathogenesis, and treatment of HIV infection. AIDS Res. Hum. Retroviruses 8, 199-207.
16. Hansen, B. D., Nara, P. L., Maheshwari, R. K., Sidhu, G. S., Bernbaum, J. G., Hoekzema, D., Meltzer, M. S., and Gendelman, H. E. (1992). Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120. J. Virol. 66, 7543-7548.
17. Hawley R. G., Sabourin, L. A., and Hawley, T. S. (1989). An improved retroviral vector for gene transfer into undifferentiated cells. Nucleic Acids Res. 17, 4001.
18. Kitamura, T., Tange, T., Terasawa, T., Chiba, S., Kuwaki, T., Miyagawa, K., Piao, Y. F., Miyazono, K., Urabe, A., and Takaku, F. (1989). Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J. Cell. Physiol. 140, 323-334.
19. Koopman, G., Reutelingsperger, C. P. M., Kuijten, G. A. M., Keekhen, R. M. J., Pals, S. T., and van Oers, M. H. J. (1994). Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1420.
20. Lane, H. C., Davey, V., Kovacs, J. A., Feinberg, J., Metcalf, J. A., Herpin, B., Walker, R., Deyton, L., Davey, R. T., and Faloon, J. (1990). Interferon-alpha in patients with asymptomatic human immunodeficiency virus (HIV) infection. Ann. Intern. Med. 112, 805-811.
21. Liu, R., Paxton, W. A., Choe, S., Ceradini, D., Martin, S. R., Horuk, R., MacDonald, M. E., Stuhlmann, H., Koup, R. A., and Landau, N. R. (1996). Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86, 367-377.
22. Lloyd, A. R., Biragyn, A., Johnston, J. A., Taub, D. D., Xu, L. L., Michiel, D., Sprenger, H., Oppenheim, J. J., and Kelvin, D. J. (1995). Granulocyte-colony stimulating factor and lipopolysaccharide regulate the expression of interleukin 8 receptors on polymorphonuclear leukocytes. J. Biol. Chem. 270, 28188-28192.
23. Loetscher, P., Seitz, M., Baggiolini, M., and Moser, B. (1996). Interleukin-2 regulates CC chemokine resceptor expression and chemotatic responsiveness in T lymphocytes. J. Exp. Med. 184, 569-577.
24. Louache, F., Debili, N., Marandin, A., Coulombel, L., and Vainchenker, W. (1994). Expression of CD4 by human hematopoietic progenitors. Blood 84, 3344-3355.
25. Macé, K., Seif, I., Anjard, C., De Maeyer-Guignard, J., Duc Dodon, M., Gazzolo, L., and De Maeyer, E. (1991). Enhanced resistance to HIV-1 replication in U937 cells stably transfected with the human IFN-β gene behind an MHC promoter fragment. J. Immunol. 147, 3553-3559.
26. Meylan, P. R. A., Guatelli, J. C., Munis, J. R., Richman, D. R., and Kornbluth, R. S. (1993). Mechanisms for the inhibition of HIV replication by interferon-α, -β, and -γ in primary human macrophages. Virology 193, 138-148.
27. Michaelis, B., and Levy, J. A. (1989). HIV replication can be blocked by recombinant human interferon beta. AIDS 3, 27-31.
28. Molina, J. M., Scadden, D. T., Sakaguchi, M., Fuller, B., Woon, A., and Groopman, J. E. (1990). Lack of evidence for infection or of effect on growth of hematopoietic progenitor cells after in vivo or in vitro exposure to human immunodeficiency virus. Blood 76, 2476-2482.
29. Moore, J. P. (1997). Coreceptors: Implications for HIV pathogenesis and therapy. Science 276, 51-52.
30. Penton-rol, G., Polentarutti, N., Luini, W., Borsatti, A., Mancinelli, R., Sica, A., Sozzani, S., and Mantovani, A. (1998). Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-γ. J. Immunol. 160, 3869-3873.
31. Pfeffer, L. M., Wang, E., and Tamm, I. (1980). Interferon inhibit the redistribution of the cell surface components. J. Exp. Med. 152, 469-474.
32. Piqueras, B., Autran, B., Debre, P., and Gorochov, G. (1996). Detection of apoptosis at single-cell level by direct incorporation of fluorescein-dUTP in DNA strand breaks. Biotechniques 20, 634-640.
33. Polentarutti, N., Allavena, P., Blanchi, G., Giardina, G., Basile, A., Sozzani, A., Mantovani, A., and Introna, M. (1997). Il-2-regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: Characterization of a predominant 3.4 kb transcripts containing CCR2B and CCR2A sequences. J. Immunol. 157, 2689-2694.
34. Samson, M., Libert, F., Doranz, B. J., Rucker, J., Liesnard, C., Farber, C. M., Saragosti, S., Lapoumeroulie, C., Cognaux, J., Forceille, C., Muyldermans, G., Verhofstede, C., Burtonboy G., Georges, M., Imai, T., Rana, S., Yi, Y., Smyth, R. J., Collman, R. G., Doms, R. W., Vassart, G., and Parmentier, M. (1996). Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382, 722-725.
35. Scadden, D. T., Zon, L. I., and Groopman, J. E. (1989). Pathophysiology and management of HIV-associated hematologic disorders. Blood 74, 1455-1463.
36. Schmidtmayerova, H., Bolmont, C., Baghdiguian, S., Hirsch, I., and Chermann, J. C. (1992). Distinctive pattern of infection and replication of HIV-1 strain in blood-derived macrophages. Virology 190, 124-133.
37. Schrier, R. D., McCutchan, J. A., Venable, J. C., Nelson, J. A., and C. A. Wiley (1993). T-cell-induced expression of human immunodeficiency virus in monocytes/macrophages. J. Virol. 64, 3280-328.
38. Seif, I., Lauret, E., and Riviere, I. (1991). Isolation of DNA from cells and from enzyme reactions. Methods Mol. Cell. Biol. 2, 216-217.
39. Shirazi, Y., and Pitha, P. M. (1993). Interferon α-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells. Virology 193, 303-312.
40. Shirazi, Y., and Pitha, P. M. (1998). Interferon downregulates CXCR4 (fusin) gene expression in peripheral blood mononuclear cells. J. Hum. Virol. 1, 69-76.
41. Valentin, A., Albert, J., Fenyo, E. M., and Asjo, B. (1990). HIV-1 infection of normal human macrophage cultures: Implication for silent infection. Virology 177, 790-794.
42. Vieillard, V., Lauret, E., Rousseau, V., and De Maeyer, E. (1994). Blocking of retroviral infection at a step prior to reverse transcription in cells transformed to constitutively express interferon β. Proc. Natl. Acad. Sci. USA 91, 2689-2693.
43. Vieillard, V., Lauret, E., Maguer, V., Jacomet, C., Rozenbaum, W., Gazzolo, L., and De Maeyer, E. (1995). Autocrine interferon-β synthesis for gene therapy of HIV infection: Increased resistance to HIV-1 in lymphocytes from healthy and HIV-infected individuals. AIDS 9, 1221-1228.
44. Vieillard, V., Cremer, I., Lauret, E., Rozenbaum, W., Debré, P., Autran, B., and De Maeyer, E. (1997). Interferon β transduction of peripheral blood lymphocytes from HIV-infected donors increases Th1-type cytokine production and improves the proliferative response to recall antigens. Proc. Natl. Acad. Sci. USA 94, 11595-11600.
45. Wu, L., Paxton, W. A., Kassam, N., Ruffing, N., Rottman, J. B., Sullivan, N., Choe, H., Sodroski, J., Newman, W., Koup, R. A., and Mackay C. R. (1997). CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185, 1681-1691.
46. Yu, M., Poescha, E., and Wong-Staal, F. (1994). Progress towards gene therapy for HIV infection. Gene Therapy 1, 13-26.
47. Zauli, G., Vitale, M., Carla Re, M., Furlini, G., Zamai, L., Falcieri, E., Gibellini, D., Visani, G., Davis, B. R., Capitani, S., and La Placa, M. (1994). In vitro exposure to human immunodeficiency virus type 1 induces apoptotic cell death of the factor-dependent TF-1 hematopoietic cell line. Blood 83, 167-175.
48. + hematopoietic progenitor cells by human immunodeficiency virus 1 or gp120 mediated by endogenous transforming growth factor β1. J. Exp. Med. 183, 99-108.