Prodrugs of CL316243: A selective β3-adrenergic receptor agonist for treating obesity and diabetes

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 14, 1999, Pages 1921-1926

  Sum, F W ^a   Gilbert, A ^a   Venkatesan, A M ^a   Lim, K ^a   Wong, V ^a   O'Dell, M ^a   Francisco, G ^a   Chen, Z ^a   Grosu, G ^a   Baker, J ^a   Ellingboe, J ^a   Malamas, M ^a   Gunawan, I ^a   Primeau, J ^a   Largis, E ^b   Steiner, K ^b  

^a Chemical Sciences   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; CL 317413; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; MONKEY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; ORAL DRUG ADMINISTRATION; RAT; STRUCTURE ACTIVITY RELATION;

ADRENERGIC BETA-AGONISTS; ANIMALS; BIOLOGICAL AVAILABILITY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIOXOLES; ESTERS; FATTY ACIDS; HALF-LIFE; HAPLORHINI; HUMANS; HYDROLYSIS; HYPOGLYCEMIC AGENTS; MICE; OBESITY; PRODRUGS; RATS;

EID: 0033584163     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00316-9     Document Type: Article

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