Nitric oxide inhibits the HIV-1 reverse transcriptase activity

Biochemical and Biophysical Research Communications

Volumn 258, Issue 3, 1999, Pages 624-627

  Persichini, Tiziana ^a   Colasanti, Marco ^a   Fraziano, Maurizio ^b   Colizzi, Vittorio ^b   Medana, Claudio ^c   Polticelli, Fabio ^a   Venturini, Giorgio ^a   Ascenzi, Paolo ^a  

^a ROMA TRE UNIVERSITY   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Enzyme inhibition; HIV 1 reverse transcriptase; Nitric oxide; NO donor

Indexed keywords

4 ETHYL 2 HYDROXYIMINO 5 NITRO 3 HEXENAMIDE; BENZENESULFONIC ACID DERIVATIVE; CYSTEINE; DIMETHYLAMINE; LINSIDOMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; OXALIC ACID; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRIAZENE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0033583811     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.0581     Document Type: Article

References (28)

1. Gait M. J., Karn J. Trends Biotechnol. 13:1995;430-437.
2. Frankel A. D., Young J. Annu. Rev. Biochem. 67:1998;1-25.
3. Larder B. A., Stammers D. K. Nature Struct. Biol. 6:1999;103-106.
4. Esnouf R., Ren J., Ross C., Jones Y., Stammers D., Stuart D. Nature Struct. Biol. 2:1995;303-308.
5. Huang H., Chopra R., Verdine G. L., Harrison S. C. Science. 282:1998;1669-1675.
6. Merluzzi V. J., Hargrave K. D., Labadia M., Grozinger K., Skoog M., Wu J. C., Shih C.-K., Eckner K., Hattox S., Adams J., Rosenthal A. S., Faanes R., Eckner R. J., Koup R. A., Sullivan J. L. Science. 250:1990;1411-1413.
7. Ren J., Esnouf R., Garman E., Somers D., Ross C., Kirby I., Keeling J., Darby G., Jones Y., Stuart D., Stammers D. Nature Struct. Biol. 2:1995;293-302.
8. Harris D., Yadav P. N. S., Pandey V. N. Biochemistry. 37:1998;9630-9640.
9. Loya S., Tal R., Hughes S. H., Hizi A. J. Biol. Chem. 267:1992;13879-13883.
10. Loya S., Gao H. Q., Avidan O., Boyer P. L., Hughes S. H., Hizi A. J. Virol. 71:1997;5668-5672.
11. Kameoka M., Okada Y., Tobiume M., Kimura T., Ikuta K. AIDS Res. Hum. Retroviruses. 12:1996;1635-1638.
12. Stamler J. S. Cell. 78:1994;931-936.
13. Stamler J. S. Curr. Top. Microbiol. Immunol. 196:1995;19-36.
14. Dimmeler S., Haendeler J., Nehls M., Zeiher A. M. J. Exp. Med. 185:1997;601-607.
15. Kim Y-M., Talanian R. V., Billiar T. R. J. Biol. Chem. 272:1997;31138-31148.
16. Mayer B., Hemmens B. Trends Biochem. Sci. 22:1997;477-481.
17. Melino G., Bernassola F., Knight R. A., Corasaniti M. T., Nisticò G., Finazzi-Agrò A. Nature. 388:1997;432-433.
18. Becker K., Savvides S. N., Keese M., Schirmer R. H., Karplus P. A. Nature Struct. Biol. 5:1998;267-271.
19. Persichini T., Colasanti M., Lauro G. M., Ascenzi P. Biochem. Biophys. Res. Commun. 250:1998;575-576.
20. Sorba G., Medana C., Fruttero R., Cena C., Di Stilo A., Galli U., Gasco A. J. Med. Chem. 40:1997;463-469.
21. de Groot H., Hegi U., Sies H. FEBS Lett. 315:1993;139-142.
22. Fukuyama S., Kita Y., Hirasawa Y., Azuma T., Sato A., Morokoshi N., Koda S., Yasuda T., Oka S., Sakurai H. Free Radical Res. 23:1995;443-452.
23. Reverse Transcriptase Assay, Nonradioactive, 1998.
24. Stamler J. S., Hausladen A. Nature Struct. Biol. 5:1998;247-249.
25. Martindale, J. 1996, 31, Pharmaceutical Press, London.
26. Hrabie J. A., Klose J. R., Wink D. A., Keefer L. K. J. Org. Chem. 58:1993;1472-1476.
27. Matthews J. R., Botting C. H., Panico M., Morris H. R., Hay R. T. Nucleic Acids Res. 24:1996;2236-2242.
28. Persichini T., Colasanti M., Fraziano M., Colizzi V., Ascenzi P., Lauro G. M. Biochem. Biophys. Res. Commun. 254:1999;200-202.