Total synthesis of (+)-himbacine and (+)-himbeline

Journal of Organic Chemistry

Volumn 64, Issue 6, 1999, Pages 1932-1940

  Chackalamannil, Samuel ^a   Davies, Robert J ^a   Wang, Yuguang ^a   Asberom, Theodros ^a   Doller, Darío ^a   Wong, Jesse ^a   Leone, Daria ^a   McPhail, Andrew T ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIMBACINE; HIMBELINE; ISOHIMBACINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL REACTION; ENANTIOMER; ISOMERISM; STEREOCHEMISTRY; SYNTHESIS;

EID: 0033583274     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo981983+     Document Type: Article

References (53)

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11. 2 ratio of 10.
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38. 4a in comparison to compound 19.
39. 9 double bond.
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48. A large excess (8-12 wt equiv) of Raney nickel was necessary. Commercially available (Aldrich) Raney nickel was washed as mentioned before (ref 17) prior to use.
49. 3)].
50. 3)].
51. 3)].
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